COSM-CEMCA

equipe COSM
chimie organique
santé et matériaux

Publications 2019-2017

Chimie Organique               Application Santé         Application Matériaux ou Coordination    

2019

Highly stable and inert complexation of Indium(III) by reinforced cyclam dipicolinate and a bifunctional derivative for bead encoding in mass cytometry
Grenier, L.; Beyler, M.; Platas-Iglesias, C.; Closson, T.; Esteban Gómez, D.; Seferos, D. S.; Liu, P.; Ornatsky, O. I.; Baranov, V. and Tripier, R.
Chemistry A Eur. J. , 2019, ASAP. DOI: 10.1002/chem.201903969
Published online 03 September 2019

Bis‐Thioether‐Containing Lipid Chains in Cationic Amphiphiles: Physicochemical Properties and Applications in Gene Delivery
Bouraoui, A.; Ghanem, R.; Berchel, M.; Vié, V.; Le Guen, Y.; Paboeuf, G.; Deschamps, L.; Le Gall, T.; Montier, T.; Jaffrès, P-A.
ChemPhysChem, 2019, 20, 2187-2194,DOI: 10.1002/cphc.201900626
Published online 08 August 2019

TE1PA as innovating chelator for 64Cu immuno-TEP imaging: a comparative in vivo study with DOTA/NOTA  by conjugation on 9E7.4 mAb in a syngeneic multiple myeloma model
Navarro, A-S.; Le Bihan, T.; Le Saëc, P.; Le Bris, N.; Bailly, C.; Saï-Maurel, C.; Bourgeois, M.; Chérel, M.; Tripier, R. and Faivre-Chauvet, A.
Bioconjugate Chem. , 2019, ASAP, DOI: 10.1021/acs.bioconjchem.9b00510
Published online August 6, 2019
 
Synthesis of Orthogonal N-Protected C-functional Side-Bridged Cyclams to give access to unsymmetrical constrained BCAs
Le Bihan, T.; Le Bris, N.; Bernard, H.; Platas-Iglesias, C.; Tripier, R.
Eur. J. Org. Chem. , 2019, ASAP, DOI: 10.1002/ejoc.201901013
Published online 01 August 2019

Antibacterial and transfection activities of nebulized formulations incorporating long n-alkyl chain silver N-heterocyclic carbene complexes
Mottais, A.; Berchel, M.; Le Gall, T.; Sibiril, Y.; d’Arbonneau, F.; Laurent, V.; Jaffrès, P.A.; Montier, T.
Inter. J. Pharm., 2019, 567, 118500, DOI: 10.1016/j.ijpharm.2019.118500
Published online 6 July 2019

Designing of a Magnetodielectric System in Hybrid Organic–Inorganic Framework, a Perovskite Layered Phosphonate MnO3PC6H4‐m‐Br⋅H2O
Basu, T.; Bloyet, C.; Beaubras, F.; Caignaert, V.; Perez, O.; Rueff, J.M.; Pautrat, A.; Raveau, B.; Lohier, J.F.; Jaffrès, P.A.; Couthon, H.; Rogez, G.; Taupier, G. and Dorkenoo, H.
Adv. Funct. Mater., 2019, 1901878, DOI: 10.1002/adfm.201901878
Published online 18 June 2019
 
Phosphate and polyphosphate anions recognition by a dinuclear copper(II) complex of an unsymmetrical squaramide
Esteves, C. V.; Costa, J.; Esteban, D.; Lamosa, P.; Bernard, H.; Platas-Iglesias, C.; Tripier, R.  and  Delgado, R. 
Dalton Trans. , 2019, ASAP, DOI: 10.1039/C9DT01434A
Published online 29 May 2019
 
What is the best radionuclide for immuno-PET of multiple myeloma? A
comparison study between 89Zr- and 64Cu-labeled anti-CD138 in a preclinical
syngeneic model.

Bailly, C.; Gouard, S.; Guérard, F.; Chalopin, B.; Carlier, T.; Faivre-Chauvet, A.; Remaud-Le Saëc, P.; Bourgeois, M.; Chouin, N.; Rbah-Vidal, L.; Tripier, R.; Haddad, F.; Kraeber-Bodéré, F.; Bodet-Milin, C.; Chérel, M.
International Journal of Molecular Sciences, 2019, 20(10), 2564, DOI: 10.3390/ijms20102564
Published online 24 May 2019

Endo- versus Exocyclic Coordination in Copper Complexes with Methylthiazolylcarboxylate Tacn Derivatives.
Guillou, A.; Lima, L.M.P.; Esteban, D.; Delgado, R.; Platas-Iglesias, C.; Patinec, V. and Tripier, R.
Dalton Trans., 2019, 48, 8740-8755 , DOI: 10.1039/C9DT01366K
Published online 17 May 2019

Lipid‐Based Quaternary Ammonium Sophorolipid Amphiphiles with Antimicrobial and Transfection Activities.
Stevens, C. V.; Delbeke, E.; Everaert, J.; Rigole, P.; Coeneye, T.; Roelants, S.; Soetaert, W.; Van Bogaert, I.; Van Geem, K.; Lozach, O.; Berchel, M.; Montier, T.; Jaffres, P.-A.; Brennich, M.; Baccile, N.
ChemSusChem, 2019, 12, 3642-3653, DOI: 10.1002/cssc.201900721
Published online 13 May 2019

A “Multi-Heavy-Atom” Approach Toward Biphotonic Photosensitizers With Improved Singlet Oxygen Generation Properties
Galland, M.; Le Bahers, T.; Banyasz, A.; Lascoux, N.; Duperray, A.; Grichine, A.; Tripier, R.; Guyot, Y.; Maynadier, M.; Nguyen, C.; Gary-Bobo, M.; Andraud, C.; Monnereau, C.; Maury O.
Chemistry Eur. J. , 2019, ASAP, DOI: 10.1002/chem.201901047
Published online 11 April 2019

Do transparent exopolymeric particles (TEP) affect the toxicity of nanoplastics on Chaetoceros neogracile?
González-Fernández, C; Toullec, J.; Lambert, C.; Le Goïc, N.; Seoane, M.; Moriceau, B.; Huvet, H.; Berchel, M.; Vincent, D.; Courcot, L.; Soudant; P.; Paul-Pont, I.
Environmental Pollution, Volume 250, 2019, 873-882, DOI: 10.1016/j.envpol.2019.04.093
Published online 25 April 2019

Aerosol Delivery to the Airways Using Cationic Lipid Nanocomplexes in a Perspective of Cystic Fibrosis Treatment
Berchel, M,; Jaffrès, P-A.; Le Gall, T.; Montier, T.
ACS Symposium Series, 2019, Volume 1309, Chapitre 2, pages 35-58, DOI: 10.1021/bk-2019-1309.ch002
Published online March 20, 2019

Substitution of unsaturated lipid chains by thioether containing lipid chains in cationic amphiphiles: physico-chemical consequences and application for gene delivery.
Bouraoui, A.; Berchel, M.; Ghanem, R.; Vié, V.; Paboeuf, G.; Deschamps, L.; Lozach, O.; Le Gall, T.; Montier T. and Jaffres P.A.
Org. Biomol. Chem., 2019, 17, 3361-3373, DOI: 10.1039/C9OB00473D
Published online 14 Mar 2019

Surface functionalization determines behavior of nanoplastic solutions in model aquatic environments
Tallec, K.; Blard, O.; González-Fernández, C.; Brotons, G.; Berchel, M.; Soudant, P.; Huvet, A.; Paul-Pont, I.
Chemosphere, 2019, 225, 639-646, DOI: 10.1016/j.chemosphere.2019.03.077
Published online 14 March 2019

Spin Cross-Over (SCO) Complex Based on Unsymmetrical Functionalized Triazacyclononane Ligand: Structural Characterization and Magnetic Properties
Halit, M.; Roger, M.; Patinec, V.; Yefsah, S.; Gómez-García, C. J. and Triki, S.
Magnetochemistry 2019, 5(1), 19, DOI: 10.3390/magnetochemistry5010019.
Published online 7 March 2019


Design and Synthesis of Hybrid PEGylated Metal Monopicolinate Cyclam Ligands for Biomedical Applications
Aouidat, F.; Halime, Z.; Moretta, R.; Rea, I.; Filosa, S.; Donato, S.; Tate, R.; De Stefano, L.; Tripier, R.; Spadavecchia, J.
ACS Omega, 2019, 4 (2), pp 2500–2509, DOI: 10.1021/acsomega.8b03266
Published online February 1, 2019

Methylthiazolyl Tacn Ligands for Copper Complexation and their BCA Derivatives for Bioconjugation and 64Cu Radiolabeling: An Example with Bombesin.
Guillou, A.; Lima, L. M. P.; Esteban-Gómez, D.; Le Poul, N.; Bartholomä, M. D.; Platas-Iglesias, C; Delgado, R.; Patinec, V. and Tripier, R.
Inorg. Chem., 2019, 58, 2669-2685, DOI : 10.1021/acs.inorgchem.8b03280
Published online January 28, 2019
 
Organophosphorus Chemistry: From Molecules to Applications (2019)
Recent Developments in Phosphonium Chemistry
Mathieu Berchel, Paul-Alain Jaffrès
Wiley- VCH, 592 pages, Editor: Viktor Iaroshenko, March 2019, ISBN: 978-3-527-33572-5

Brevet

Restricted-​geometry nitrogen macrocyclic ligands as complexing agents for radiotherapy and radiodiagnostics.
Tripier, R.; Rousseaux, O.; Le Fur, M.; Beyler, M.; Fougere, O.
Assignee: Guerbet, Fr.; Centre National de la Recherche Scientifique; Universite de Bretagne Occidentale
Brevet: Jan 4, 2019, FR 3068355, A1, Application: Jun 28, 2017
FR 2017-55933
Extension: Jan 3, 2019, WO 2019002505, Application: Jun 28, 2018, WO 2018-EP67482
 

2018

Dendritic Cell Targeting mRNA Lipopolyplexes combine strong antitumor T‑Cell immunity with improved inflammatory safety.
K. Van der Jeught, S. De Koker, L. Bialkowski, C. Heirman, P. Tjok Joe, F. Perche, S. Maenhout, S. Bevers, K. Broos, K. Deswarte, V. Malard, H. Hammad, P. Baril, T. Benvegnu, P.A. Jaffrès, S. A. A. Kooijmans, R. Schiffelers, S. Lienenklaus, P. Midoux, C. Pichon, K. Breckpot, K. Thielemans
ACS Nano, 2018, 12 (10), pp 9815–9829, DOI:10.1016/j.jconrel.2018.03.035
Published online September 26, 2018

Incipient spin-dipole coupling in a 1D helical-chain metal-organic hybrid
Basu, T.; Bloyet, C.; Rueff, J.M.; Caignaert, V.; Pautrat, A.; Raveau, B.; Rogez, G.; Jaffrès, P.A.
J. Mater. Chem. C, 2018, 6, 10207-10210 , DOI: 10.1039/C8TC04328K
Published online 13 Septembre 2018

One-Dimensional Fluorene-Based Co(II) Phosphonate Co(H2O)2PO3C–C12H9·H2O: Structure and Magnetism
Bloyet, C.; Rueff, J.M.; Perez, O.; Pautrat, A.; Caignaert, V.; Raveau, B.; Rogez, G.; Jaffrès, P.A.
Inorganics 2018, 6(3), 93 , DOI: 10.3390/inorganics6030093
Published online 5 September 2018

Manganese Fluorene Phosphonates: Formation of Isolated Chains
Bloyet, C.; Rueff, J.M.; Caignaert, V.; Raveau, B.; Lohier, J.F.; Roger, M.; Rogez, G.; Jaffrès, P.A.
Inorganics 2018, 6(3), 92 , DOI: 10.3390/inorganics6030092
Published online 5 September 2018

Nanoplastics impaired oyster free living stages, gametes and embryos
Tallec, K.; Huvet, A.; Di Poi, C.; González-Fernández, C.; Lambert, C.; Petton, B.; Le Goïc, N.; Berchel, M.; Soudant, P.; Paul-Pont, I.
Environ. Pollut., 2018, 1226-1235, DOI: 10.1016/j.envpol.2018.08.020
Published online 8 August 2018
 
Excimer and Red Luminescence Due to Aggregation-Induced
Emission in Naphthalene Based Zinc Phosphonate

Bloyet, C.; Rueff, J.M.; Cardin, J.; Caignaert, V.; Doualan, J.L.; Lohier, J.F.; Jaffrès, P.A.; Raveau B.
Eur. J. Inorg. Chem., 2018, 3095-3103, DOI: doi.org/10.1002/ejic.201800369.
Published online 28 June 2018

Cellular responses of Pacific oyster (Crassostrea gigas) gametes exposed in vitro to
polystyrene nanoparticles

Gonzalez-Fernandeza, C,; Tallec, K.; Le Goica, N.; Lambert, C.; Soudant, P.; Huvet, A.; Suquet, M.; Berchel, M. et Paul-Pont, I.
Chemosphere, 2018, 764-772, DOI: 10.1016/j.chemosphere.2018.06.039
Published online 6 June 2018

Synthesis and biological evaluation of bolaamphiphilic sophorolipids
Delbeke, E.I. P.; Everaert, J.; Lozach, O.; Le Gall, T.; Berchel, M.; Montier, T.; Jaffrès, P.A.; Rigole, P.; Coenye, T.; Brennich, M.; Baccile, N.; Roelants, S.; Soetaert, W.; Van Bogaert, I. N. A.; Marcel Van Geem, K.; and Stevens, C.V.
ACS Sus. Chem. & Engineering, 2018, 6, 8992–9005, DOI: 10.1021/acssuschemeng.8b01354
Published online May,21, 2018

Expanding the Family of Pyclen-Based Ligands Bearing Pendant Picolinate Arms for Lanthanide Complexation.
Le Fur, M.; Molnár, E.; Beyler, M.; Kálmán, F. K.; Fougère, O.; Esteban-Gómez, D.; Rousseaux, O.; Tripier, R.; Tircsó, G. and Platas-Iglesias, C.
Inorg. Chem., 2018, 6932–6945, DOI: 10.1021/acs.inorgchem.8b00598
Published online 30 May 2018

Combining pyclen framework with conjugated antenna for the design of europium and samarium luminescent bioprobes.
Hamon, N., Galland, M.; Le Fur, M.; Roux, A.; Duperray, A.; Grichine, A.; Andraud, C.; Le Guennic, B.; Beyler, M.; Maury, O. and Tripier, R.
Chem. Comm., 2018, 6173-6176 , DOI: 10.1039/c8cc02035c
Published online 30 May 2018

Steric Effects on the Binding of Phosphate and Polyphosphate Anions by Zinc(II) and Copper(II) Dinuclear Complexes of m-Xylyl-bis-cyclen.
Esteves, C. V.; Esteban-Gómez, D.; Platas-Iglesias, C.; Tripier, R.; Delgado R.
Inorg. Chem., 2018, 6466–6478, DOI: 10.1021/acs.inorgchem.8b00539.
Published online May 11, 2018

Preclinical evaluation of mRNA trimannosylated lipopolyplexes as therapeutic cancer vaccines targeting dendritic cells.
Le Moignic, A.; Malard, V.; Benvegnu, T.; Lemiègre, L.; Berchel, M.; Jaffrès, P.-A.; Baillou, C.; Delost, M.; Macedo, R.; Rochefort, J.; Lescaille, G.; Pichon, C.; Lemoine, F.M.; Midoux, P. and Mateo, V.
J. Controlled Release, 2018, 100-121, DOI:10.1016/j.jconrel.2018.03.035
Published online 28th May 2018

Synthesis of a C-functionalized TE1PA and comparison with analogues. Example of bioconjugation on 9E7.4 mAb for multiple myeloma 64Cu-PET imaging.
Le Bihan, T.; Navarro, A-S.; Le Bris, N.; Le Saëc, P.; Gouard, S.; Haddad, F.; Gestin, J-F.; Chérel, M.; Faivre-Chauvet, A. and Tripier, R.
Org. Biomol. Chem., 2018, 4261-4271, DOI: 10.1039/C8OB00499D
Publish online 10 April 2018

Kinetics is crucial when targeting copper ions to fight Alzheimer’s disease: an illustration with azamacrocyclic ligands.
Conte-Daban, A,; Beyler, M.; Tripier, R. and Hureau C.
Chem. Eur. J, 2018, 8447-8452, DOI: 10.1002/chem.201801520
Publish online 3 April 2018

Synthesis of Alkyl-Glycerolipids Standards for Gas Chromatography Analysis: Application for Chimera and Shark Liver Oils.
Pinault, M.; Guimaraes, C.; Couthon, C.; Thibonnet, J.; Fontaine, D.; Chantôme, A.; Chevalier, S.; Besson, P.; Jaffrès, P.A. et Vandier, C.
Marine Drugs, 2018, 16, 101, DOI: 10.3390/md16040101
 

Stable and Inert Yttrium(III) Complexes with Pyclen-Based Ligands Bearing Pendant Picolinate Arms: Toward New Pharmaceuticals for β-Radiotherapy
Le Fur, M.; Beyler, M.;; Molnár, E.; Fougère, O.; Esteban-Gómez, D.; Tircsó, G.; Platas-Iglesias, C.; Lepareur, N.; Rousseaux, O. and Tripier R.
Inorg. Chem., 2018, 57 (4), pp 2051–2063, DOI: 10.1021/acs.inorgchem.7b02953
Published online 5 February 2018

 

Comparison of Immuno-PET of CD138 and PET imaging with 64CuCl2 and 18F-FDG in a preclinical syngeneic model of multiple myeloma.
Bailly, C.; Gouard, S.; Lacombe, M.; Remaud-Le Saëc, P.; Chalopin, B.; Bourgeois, M.; Chouin, N.; Tripier, R.; Halime, Z.; Haddad, F.; Faivre-Chauvet, A.; Kraeber-Bodéré, F.; Chérel, M.; Bodet-Milin, C.
Oncotarget, 2017, 9:9061-9072, DOI : 10.18632/oncotarget.23886
Published online: January 3rd 2018

A Coordination Chemistry Approach to Fine-Tune the Physicochemical Parameters of Lanthanide Complexes Relevant to Medical Applications.
Le Fur, M.; Molnár, E.; Beyler, M.; Kálmán, F. K..; Fougère, O.; Esteban-Gómez, D.; Rousseaux, O.; Tripier, R.; Tircsó, Gy. and Platas-Iglesias, C.
Chemistry Eur. J., 2018, 24, 13, 3127-3131 , DOI : A0.1002/chem. 201705528
 

2017

 Antibacterial Effect and DNA Delivery Using a Combination of an Arsonium-​Containing Lipophosphoramide with an N-​Heterocyclic Carbene-​Silver Complex - Potential Benefits for Cystic Fibrosis Lung Gene Therapy.
Mottais, A.; Sibiril, Y.; Laurent, V.; Berchel, M.; Jaffres, P.-A.; Gill, D.; Hyde, S.; Montier, T.; Le Gall, T.
International journal of pharmaceutics, 2017, 29-41, DOI: 10.1016/j.ijpharm.2017.11.022

Phosphonic acid: preparation and applications
Sevrain, C.M.; Berchel, M.; Couthon, H. and Jaffrès, P.A.
Beilstein J. Org. Chem., 2017, 13, 2186-2213 , DOI: 10.3762/bjoc.13.219

 Singular Interaction between an Antimetastatic Agent and the Lipid Bilayer: The Ohmline Case.
Herrera, F.E.; Sevrain, C.M.; Jaffrès, P.A.; Couthon, H.; Grélard, A.; Dufourc, E.J.; Chantôme, A.; Potier-Cartereau, M.; Vandier, C.; Bouchet A. M.
ACS Omega, 2017, 2, 6361-6370, DOI: 10.1021/acsomega.7b00936.

Layered Simple Hydroxides Functionalized by Fluorene-Phosphonic Acids: Synthesis, Interface Theoretical Insights, and Magnetoelectric Effect.
Evrard, Q.; Chaker, Z.; Roger, M.; Sevrain, C.M.; Delahaye, E.; Gallart, M.; Gilliot, P.; Leuvrey, C.; Rueff, J-M.; Rabu, P.; Massobrio, C.; Boero, M.; Pautrat, A.; Jaffrès, P-A.; Ori, G.; Rogez, G.
Advanced Functional Materials, 2017, accepted, DOI: 10.1002/adfm.201703576
First published online 11 September 2017

The role of the capping bond effect on pyclen natY3+/90Y3+ chelates: full control of the regiospecific N-functionalization makes the difference
Le Fur, M.; Beyler, M.; Molnár, E.; Fougère, O.; Esteban-Gómez, D.; Tircsó, G.; Platas-Iglesias, C.; Lepareur, N.; Rousseaux O. and Tripier, R.
Chem. Commun., 2017, 53, 9534-9537, DOI: 10.1039/C7CC05088G.
Published online 3 August 2017

Tuning the copper(II) coordination properties of cyclam by subtle chemical modifications.
Camus, N.; Le Bris, N.; Nuryyeva, S.; Chessé, M.; Esteban-Gómez, D.; Platas-Iglesias, C.; Tripier R. and Elhabiri, M.
Dalton Trans., 2017, 46, 11479-11490 , DOI: 10.1039/C7DT00750G
Published online 27 July 2017

Synthesis of α-amino-lipophosphonates as cationic lipids or co-lipids for DNA transfection in dendritic cells.
Berchel, M.; Akhter, S.; Berthe, W.; Gonçalvez, C.; Dubuisson, M.; Pichon, C.; Jaffres, P-A. and Midoux P.
J. Mater. Chem. B, 2017, 5, 6869, DOI: 10.1039/C7TB01080J.
Published online 15 June 2017

Tacn‑based Bifunctional Picolinate Ligands for an Efficient Copper Complexation.
Guillou, A,; Lima, L. M. P.; Roger, M.; Esteban-Gómez, D.; Delgado, R.; Platas-Iglesias, C.; Patinec, V. and Tripier, R.
Eur. J. Inorg. Chem., 2017, 18, 2435-2443, DOI: 10.1002/ejic.201700176
Published online

Near Infrared Two photon Imaging using a Bright Cationic Yb(III) Bioprobe Spontaneously Internalized into Live Cells
Bui, A. T.; Beyler, M.; Grichine, A.; Duperray, A.; Mulatier, J.-C.; Guyot, Y. ; Andraud, C.; Tripier, R.; Brasselet, S.; Maury, O.
Chem Commun., 2017, 53, 6005-6008, DOI: 10.1039/C7CC02835K
Published online 9 May 2017
 

Investigation of the complexation of natZr(IV) and 89Zr(IV) by hydroxypyridinones for the development of chelators for PET imaging applications.
Guérard, F.; Beyler, M.; Lee, Y-S.; Tripier, R.; Gestin, J-F. and Brechbiel, M. W.
Dalton Transactions, 2017, 46, 4749-4758 , DOI: 10.1039/C6DT04625H
Published online 10 March 2017

Spectroscopic properties of a family of mono- to trinuclear lanthanide complexes.
Sy, M.; Esteban-Gómez, D.; Platas-Iglesias, C.; Rodríguez-Rodríguez, A.; Tripier, R. and Charbonnière, L. J.
Eur. J. Inorg. Chem., 2017, 14, 2122–2129, DOI: 10.1002/ejic.201601516.
Published online: 15 February 2017

Self-assembling complexes between binary mixtures of lipids with different linkers and nucleic acids promote universal mRNA, DNA and siRNA delivery.
Colombani, T.; Peuziat, P.; Dallet, L.; Haudebourg, T.; Mével, M.; Berchel, M.; Lambert, O.; Habrant, D.; Pitard, B.
Journal of Controlled Release, 2017, 249, 131–142, DOI: 10.1016/j.jconrel.2017.01.041.
Published online 1 February 2017

 Cyclam te1pa for 64Cu PET imaging. Bioconjugation to antibody, radiolabeling and preclinical application in xenografted colorectal cancer.
Frindel, M.; Le Saëc, P.; Beyler, M.; Navarro, A.-S.; Saï-Maurel, C.; Alliot, C.; Chérel, M.; Gestin, J.-F.; Faivre-Chauvet, A. and Tripier, R.
RSC Advances, 2017, 7, 9272-9283 DOI: 10.1039/c6ra26003a.
Published online 31 Jan 2017

Fluorenyl Zinc Phosphonate Zn(H2O)PO3–C13H9·H2O: Hybrid Columnar Structure with Strong C–H···π Interactions.
Bloyet, C.; Rueff, J-M.; Caignaert, V.; Lohier, J-F.; Cardin, J.; Jaffres, P-A.; Raveau, B.
ZAAC, 2017, 643, 250–255 , DOI: 10.1002/zaac.201600362
Published online 23 December 2016

Definition of the Labile Capping Bond Effect in Lanthanide Complexes.
Rodríguez-Rodríguez, A.; Regueiro-Figueroa, M.; Esteban-Gómez, D. ; Patinec, V.; Tripier, R.; Tircsó, G.; Carniato, F.; Botta M. and Platas‑Iglesias C.
Chemistry A Eur. Journal, 2016, 23 (15), 1110-1117, DOI: 10.1002/chem.201604390.
Published online November 8th 2016
 

 Brevet

Macrocyclic ligands with picolinate groups, their complexes like their medical uses.
Le Fur, M.; Tripier, R.; Rousseaux, O.; Beyler, M.
Brevet n° FR 3046172, Application n° FR 2015-63346, dépôt le 24 Décembre 2015
Extension Brevet n° WO 2017109217, Application n° WO 2016-EP82644, dépôt le 23 Décembre 2016

 Nouveaux lipides amphiphiles ramifiés
Jaffrès, P.A.; Couthon-Gourvès, H.; Afonso, D.; Montier, T.; Le Gall, T.
Brevet, Patent n° 3041643 Application n° FR 2015-59066, dépôt le 25 septembre 2015.
Extension Patent n° WO 2017051129, application n° WO 2016-FR52410
 

Publications

Equipe COSM

Contacts

Thématique: Phosphore, Lipides et Vectorisation

 Prof. Paul-Alain Jaffrès

UMR-CNRS 6521
 Université de Bretagne Occidentale
6, avenue Victor le Gorgeu.
29238 BREST Cedex 3

Tel : (00 33) (0)2 98 01 61 53
Fax : (00 33) (0)2 98 01 70 01
e-mail : pjaffres@univ-brest.fr

 

Thématique: Macrocycles Azotés et Coordination

Prof. Raphaël Tripier

UMR-CNRS 6521
Université de Bretagne Occidentale
6, avenue Victor le Gorgeu.
29238 BREST Cedex 3


Tel : (00 33) (0)2 98 01 61 38
Fax : (00 33) (0)2 98 01 70 01
e-mail : Raphael.Tripier@univ-brest.fr