Mickaël DROGUET
Maître de conférences
EA 4324 ORPHY
Laboratoire de physiologie ORPHY, site Médecine
22 av Camille Desmoulins, CS 93837,
29238 BREST cedex 3
Tél: 02.98.01.65.66
Thématiques de recherche/Compétences:
Etude du sepsis avec une approche in vivo et in vitro sur des fibres musculaires striées chez le rat et étude de l’effet protecteur potentiel d’extraits d’halophytes sélectionnés pour leurs propriétés antioxydantes
Publications:
Droguet M., Devauchelle, N., Pennec J.P., Quinn B., and Dorange G. (2012). Cultured heart cells from oyster: an experimental approach for evaluation of the toxicity of the marine pollutant tributyltin. Aquat. Living Resour. 25, 185–194
Guillouet M, Rannou M., Giroux-Metges M.G., Droguet M. and Pennec J.P. (2013). Tumor Necrosis Factor alpha induced hypoexcitability in rat muscle evidenced in a model of ion currents and action potential corresponding. Cytokine. 64(1)165-171.
Guillouët M. ; Mohammed Saïd K.; Droguet M.; Rannou F.; Pennec J.P. and Giroux-Metges M.A (2013) Sepsis and tumor necrosis factor-alpha alter the contractile properties and fatigability of rat diaphragm. Fundamental & clinical pharmacology. 27: 86
Derbré F., Droguet M., Léon K., Troadec S., Pennec J.P., Giroux-Metges M.A. et Rannou F. (2016) Single Muscle Immobilization Decreases Single-Fibre Myosin Heavy Chain Polymorphism: Possible Involvement of p38 and JNK MAP Kinases. PloS One 11(7):1-16
Talarmin H., Lefeuvre L., Droguet M., Giroux-Metges M.A., Pennec J.P., Leon K. and Derbré F. (2016) Diaphragm is better protected from oxidative stress than hindlimb skeletal muscle during CLP-induced sepsis. Redox Report 6:1-9
Bettaib J., Talarmin H., Droguet M., Magné C., Boulaaba M., Giroux-Metges M.A. and Ksouri R. (2017)Tamarix gallica phenolics protect IEC-6 cells against H 2 O 2 induced stress by restricting oxidative injuries and MAPKs signaling pathways. Biomed Pharmather 89: 490-498.
Jaballi I, Saad H.B., Bkhairia I, Kammoun I, Droguet M, Magné C, Boudawara T, Kallel C, Nasri M, Hakim A and Ben Amara I (2017). Increasing maneb doses induces reactive oxygen species overproduction and nephrotoxicity in adult mice. Toxicol Mec Method 27(5): 382-393
