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laboratoire orphy
optimisation des régulations

Michaël THERON

Maître de conférences en physiologie

EA 4324 ORPHY, Département de biologie
UFR Sciences et Techniques,
Université Européenne de Bretagne, Université de Brest
6 avenue LE GORGEU, CS 93837,
29238 BREST cedex 3

Tel: fax:

 Thématiques de recherche / compétences:

Effets de contraintes (pression hydrostatique, pression gaz, contaminants, pathologie) sur les fonctions physiologiques (bioénergétique, transport de gaz, physiologie vasculaire, homéostasie cellulaire).

Collaborations :

CHRU de Brest / Hémarina

Cedre / Lemar UBO / IFREMER Brest / TOTAL Fluides

Lab of Cell Biology and Histology, University of the Basque Country, Spain

LIENSs UMR 6250, CNRS-Université de la Rochelle

Akvaplan-niva High North Research Centre Tromsø, Norway

Projets financés:

Projet Européen PHYPODE FP7-PEOPLE-2010-ITN



Projet pilote européen PRAGMA 07.030900/2005/429172/SUB/A5

Publications pertinentes:

Wang Q., Belhomme M., Guerrero F., Mazur A., Lambrechts K.,Theron M. (2013) Diving under a Microscope - a New Simple and Versatile In Vitro Diving Device for Fluorescence and Confocal Microscopy Allowing the Controls of Hydrostatic pressure, Gas Pressures and Kinetics of Gas Saturation. Microscopy and Microanalysis, 19(3): 608-616

Lambrechts K., Pontier J.M., Balestra C., Mazur A., Theron M., Wang Q., Mansourati J., Guerrero F. (2013) Effect of a single open sea air scuba dive on human micro- and macro- vascular function. European Journal of Applied Physiology. In press DOI 10.1007/s00421-013-2676-x

Dussauze, M., Lefloch, N., Le Floch, S., Merlin, F-X., Theron, M., Pichavant-Rafini, K. (2013) Toxicity of oil-dispersant mixtures on juveniles sea bass (Dicentrarchus labrax). AMOP. 2013, 423-432.

Claireaux G., Theron M., Prineau M., Dussauze M., Merlin FX., Le-Floch S. (2013) Effects of oil exposure and dispersant use upon environmental adaptation performance and fitness in the European sea bass, Dicentrarchus labrax. Aquatic Toxicology. Vol. 130-131 April 15, 2013. p. 160-170.

Ruiz P., Ortiz-Zarragoitia M., Orbea A., Theron M., Le Floch S., Cajaraville M.P. (2012) Responses of conventional and molecular biomarkers in turbot Scophthalmus maximus exposed to heavy fuel oil nº 6 and styrene. Aquatic Toxicology, 116-117:116-28

Milinkovitch T, Godefroy J, Theron M, Thomas-Guyon H (2011) Toxicity of dispersant application: antioxidant response in gills of juvenile golden grey mullet (Liza aurata). Environmental Pollution, 159, 10 (2011) 2921-2928.

Goanvec C, Poirier E, Le Floch S, Theron M (2010) Branchial structure and hydromineral equilibrium in juvenile turbot (Scophtalmus maximus) exposed to heavy fuel oil. Fish physiol. Biochem 37(3):363-371 ; DOI 10.1007/s10695-010-9435-2

Evrard E, Marchand J, Theron M, Pichavant K, Durand G, Quiniou L, Laroche J (2010) Impacts of mixtures of herbicides on molecular and physiological responses of the European flounder Platichthys flesus. Comp. Biochem. Physiol. Part C. 152 (2010) 321-331

Merlin, F.X., Le Floch, S., Dussauze, M., Théron, M., Quentel, C., Thomas, H. (2010) Discobiol program: Investigation of dispersant use in coastal and estuarine waters. AMOP. 2, 1267-1278.

Fouchs A., Ollivier H., Theron M., Roy S., Calves P., Pichavant-Rafini K. (2009) Involvement of respiratory chain in RVD process in turbot hepatocytes. Biochem Cell Biol. 2009 Jun 87(3):499-504

Goanvec C., M. Theron, T. Lacoue-Labarthe, E. Poirier, J. Guyomarch, S. Le-Floch, J. Laroche, L. Nonnotte & G. Nonnotte. (2008) Flow cytometry for the evaluation of chromosomal damage in turbot Psetta maxima (L.) exposed to the dissolved fraction of heavy fuel oil in sea water: A comparison with classical biomarkers. J.Fish Biol. 73, 395-413

Heylen E., Guerrero F., Mansourati J., Theron M., Thioub S. and Saïag B. (2008) Effect of training frequency on endothelium-dependent vasorelaxation in rat. Eur J. Cardiovasc. Prev. & Rehab. 15(1):52-58.

Goanvec C., Theron M. An approach to the effects of oil spills pollution on fish. (2004) Oceanis 30(3) 393-421.

Goanvec C., Theron M., Poirier E., Le Floch S., Laroche J., Nonnotte L., Nonnotte G. (2004) Evaluation of chromosomal damage by flow cytometry in turbot (Scophthalmus maximus L.) exposed to fuel oil. Biomarkers 9(6) November-December 2004 435 - 446

Sébert P., Theron M, Vettier A. (2004) Pressure and temperature interactions on cellular respiration: a review. Cell. Mol. Biol. 50, 491-500.

Theron M., Sébert P. (2003) Hydrostatic pressure and cellular respiration : are the values observed post decompression representative of the reality under pressure ? Mitochondrion, 3 (2) pp 75-81

Sébert P., Theron M. (2001) Why the eel, and not the trout, can migrate under pressure ? Mitochondrion 1 : 79-85

Guerrero F., Theron M. and Sébert P. (2000) In vitro reactivity of ventral aorta to acetylcholine and noradrenaline in yellow freshwater eel (Anguilla anguilla L.) acclimatised to 10.1 MPa hydrostatic pressure. Can.J.Physiol.Pharmacol 78(11) 897-903.

Theron M., Guerrero F. and Sébert P. (2000) Improvement in the efficiency of oxidative phosphorylation in the freshwater eel acclimated to 10.1 MPa hydrostatic pressure. J.Exp.Biol. 203, 3019-3023