Professeur des Universités
en Toxicologie de l'Environnement

Enseignant-chercheur (CNU 68)
Etablissement : Institut Universitaire Européen de la Mer
Affectation de recherche : LEMAR (Laboratoire des sciences de l'environnement marin)

Equipe(s) : PANORAMA
Pour la messagerie : pré
Tél.02 98 49 86 49

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Publications (à partir de 2002) dans revues à comité de lecture international (rang A)
1. Evariste L., Rioult D., Brousseau P., Geffard A., David E. Auffret M., Fournier M., Betoulle S. 2017. Differential sensitivity to cadmium of immunomarkers measured in hemocyte subpopulations of zebra mussel Dreissena polymorpha. Ecotoxicology and Environmental Safety 137: 78-85
2. Evariste L., Auffret M., Audonnet S., Brousseau P., Geffard A., David E., Fournier M., Betoulle S. 2016. Functional features of hemocyte subpopulations of the invasive mollusk species Dreissena polymorpha. Fish & Shellfish immunology 56: 144-154
3. Kerambrun E., Rioult D., Delahaut L., Evariste, L., Pain-Devin S., Auffret M., Geffard A., David E. 2016. Variations in gene expression levels in four European zebra mussel populations in relation to metal bioaccumulation: a field study. Ecotoxicology and Environmental Safety 134: 53-63
4. Akcha F., Barranger•A., Bachère E., Heude Berthelin C., Piquemal D., Alonso P., Rondon Sallan R., Dimastrogiovanni G., Porte C., Menard D., Szczybelski A., Benabdelmouna A., Auffret M., Rouxel J., Burgeot T. 2016. Effects of an environmentally relevant concentration of diuron on oyster genitors during gametogenesis: responses of early molecular and cellular markers and physiological impacts. Environ. Sci. Pollut. Res. DOI 10.1007/s11356-015-5969-2
5. Caza F., Betoulle S., Auffret M., Brousseau P., Fournier M., St-Pierre Y. 2015. Comparative analysis of hemocyte properties from Mytilus edulis desolationis and Aulacomya ater in the Kerguelen Islands. Mar Environmental Res 110: 174-182
6. Lacaze E., Pedelucq J., Fortier M., Brousseau P., Auffret M., Budzinski H., Fournier M. 2015. Genotoxic and immunotoxic potential effects of selected psychotropic drugs and antibiotics on blue mussel (Mytilus edulis) hemocytes. Environmental Pollution 202: 177-186
7. Galland C., Dupuy C., Loizeau V., Danion D., Auffret M., Quiniou L., Laroche J., Pichereau P. 2015 Proteomic analysis of the European flounder Platichthys flesus response to experimental PAH-PCB contamination. 2015. Mar. Poll. Bull. 95 (2): 646-657
8. Lacroix, C., Richard, G., Seguineau, C., Guyomarch, J., Moraga, D., Auffret, M. 2015. Active and passive biomonitoring suggest metabolic adaptation in blue mussels (Mytilus spp.) chronically exposed to a moderate contamination in Brest harbor (France). Aquatic Toxicology 162: 126-137
9. Lacroix, C., Le Cuff, N., Receveur, J., Moraga, D., Auffret, M. and Guyomarch, J., 2014. Development of an innovative and ”green” stir bar sorptive extraction-thermal desorption-gas chromatography-tandem mass spectrometry method for quantification of polycyclic aromatic hydrocarbons in marine biota. Journal of Chromatography A, 1349, 1–10.
10. Lacroix, C., Coquillé, V., Guyomarch, J., Auffret, M. and Moraga, D., 2014. A selection of reference genes and early-warning mRNA biomarkers for environmental monitoring using Mytilus spp. as sentinel species. Marine Pollution Bulletin, 86, 304–313.
11. Dudognon, T., Lambert, C., Quere, C., Auffret, M., Soudant, P., Kraffe, E. 2014. Mitochondrial activity, hemocyte parameters and lipid composition modulation by dietary conditioning in the Pacific oyster Crassostrea gigas. Journal of Comparative Physiology B : Biochemical, Systemic, and Environmental Physiology 184, 303-317.
12. Haberkorn H., Lambert C, Le Goïc N, Quéré C, Bruneau A, Riso R, Auffret M, Soudant P. 2014. Cellular and biochemical responses of the oyster Crassostrea gigas to controlled exposures to metals and Alexandrium minutum. Aquatic Toxicology 147:158-67
13. Dudognon, T., Soudant, P., Seguineau, C., Quéré, C., Auffret, M., Kraffe, E. 2013. Functional capacities of gill mitochondria in oyster Crassostrea gigas during an emersion/immersion tidal cycle. Aquatic Living Resources 26, 249-256.
14. Bruneau A., Fortier M., Gagne F., Gagnon C., Turcotte P., Tayabali A., Davis T.A., Auffret M., Fournier M. 2013. In Vitro Immunotoxicology of Quantum Dots and comparison with dissolved Cadmium and Tellurium. Environmental Toxicol. 30 (1): 9-25
15. Farcy E., Burgeot T., Haberkorn H., Auffret A., Lagadic L., Allenou J.-P., Budzinski H., Mazzella N., Pete R., Heydorff M., Menard D., Mondeguer F. and Caquet T. 2013. An integrated environmental approach to investigate biomarker fluctuations in the blue mussel Mytilus edulis L. in the Vilaine estuary, France." Environmental Science and Pollution Research – Special Publication: 20 (2) : 630-650
16. Silva-Aciares F., Moraga D., Auffret M., Tanguy A., Riquelme C. 2013. Transcriptomic and cellular response to bacterial challenge (pathogenic Vibrio parahaemolyticus) in farmed juvenile Haliotis rufescens fed with or without probiotic diet. J Invertebr Pathol. 113(2):163-176
17. Bruneau A. , M. Fortier, F. Gagne, C. Gagnon, P. Turcotte, A. Tayabali, T. L. Davis, M. Auffret and M. Fournier. 2013. Size distribution effects of cadmium tellurium quantum dots (CdS/CdTe) immunotoxicity on aquatic organisms. Environ. Sci.: Processes Impacts, online paper DOI: 10.1039/C2EM30896G
18. Galland C., Dupuy C., Capitaine C., Auffret M., Quiniou L., Laroche J. and Pichereau V. 2013. Comparisons of liver proteomes in the European flounder Platichthys flesus from three contrasted estuaries. Journal of Sea Research 75: 135–141
19. Bado-Nilles A., Renault T., Faury N., Le Floch S., Quentel C., Auffret M. and Thomas-Guyon H. 2009.In vivo effects of LCO soluble fraction on immune-related functions and gene transcription in the Pacific oyster, Crassostrea gigas (Thunberg). Aquatic Toxicology 97 (3): 196-203.
20. Bado-Nilles A., Quentel C., Auffret M., Le Floch S., Gagnaire B., Renault T. and Thomas-Guyon H. 2009. Immune effects of HFO on European sea bass, Dicentrarchus labrax, and Pacific oyster, Crassostrea gigas. Ecotoxicology and Environmental Safety 72: 1446-1454.
21. Duchemin M., Wessel N., Fournier M. and Auffret M. 2008. Flow cytometric measurement of the clearance rate in Mytilus edulis and the development of a new individual exposure system for aquatic immunotoxicological studies. Environmental Pollution 153: 492-496.
22. Duchemin, M., Auffret, Wessel N., Fortier M., Morin Y, Pellerin J. and M. Fournier, M. 2008. Multiple experimental approaches of immunotoxic effects of mercury chloride in the blue mussel, Mytilus edulis, through in vivo, in tubo and in vitro exposures. Environmental Pollution 153: 416-423.
23. Gagnaire B., Duchemin M., Auffret M., Thomas-Guyon H. and Renault T. 2008. Comparison of hemocyte parameters in the pericardial cavity and the adductor muscle sinus in the Pacific oyster, Crassostrea gigas, using two types of flow cytometers. Aquat. Living Resour. 21: 39-43
24. Champeau O., Auffret M., Cajaraville M. P., Basseres A. & Narbonne J. F. 2007. Immunological and cytotoxicological responses of the Asian clam, Corbicula fluminea (M.), experimentally exposed to cadmium. Biomarkers, 12, 173-187.
25. Duchemin, M., Fournier, M. and Auffret, M. 2007. Seasonal variations of immune parameters in diploid and triploid pacific oysters, Crassostrea gigas (Thunberg). Aquaculture, 264: 73-81
26. Auffret M., Rousseau S., Boutet I., Tanguy A., Baron J., Moraga D and Duchemin M. 2006. A multiparametric approach for monitoring immunotoxic responses in mussels from contaminated sites in Western Mediterranea. Ecotoxicology and Environmental Safety 63: 393-405.
27. Allam B., Paillard C., Auffret M. & Ford S. 2006. Effects of the pathogenic Vibrio tapetis on defence factors of susceptible and non-susceptible bivalve species: II. Cellular and biochemical changes following in vivo challenge. Fish and Shellfish Immunology 20: 384-397
28. Le Dréan G., Auffret M., Arnold F., Sibiril Y., Arzur D., Parent-Massin D. 2005. Myelotoxicity of trichothecenes and apoptosis: an in vitro study on human cord blood CD34+ hematopoietic progenitor. Toxicology in Vitro 19: 1015-1024
29. Auffret M., Duchemin M., Rousseau S., Boutet I., Tanguy A., Moraga D., Marhic A. 2004. Monitoring of immunotoxic responses in oysters reared in areas contaminated by the "Erika" oil spill. Aquatic Living Resources 17 (3): 297-302.
30. Tanguy, A., Boutet, I., Riso, R., Boudry, P., Auffret, M. & Moraga, D. 2003. Metallothionein genes in the European flat oyster Ostrea edulis: a potential ecological tool for environnement monitoring?. Mar. Ecol. Prog. Ser. 257:87-97.
31. Corporeau C. and Auffret M. 2003. In situ hybridization for flow cytometry: A molecular method for monitoring stress-gene expression in hemolymph cells of oysters. Aquatic Toxicology 64: 427-435.
32. Cochennec-Loreau N., Auffret M., Renault T. and Langlade A. 2003. Changes in circulating and tissue-infiltrating hemocyte parameters of European flat oysters, Ostrea edulis, naturally infected with Bonamia ostreae. Journal of Invertebrate Pathology 83: 23-30.
33. Boutet, I., Tanguy A., Rousseau S., Auffret M. and Moraga, D. 2003. Molecular identification and expression of heat shock cognate (HSC70) and heat shock protein (HSP70) genes in the Pacific oyster Crassostrea gigas. Cell Stress and Chaperones 8 (1): 76¬85.
34. Auffret M., Mujdzic N., Corporeau C. and Moraga D. 2002. Xenobiotic-induced immunomodulation in the European flat oyster. Marine Environmental Research 54: 585-589
35. Laroche J., Quiniou L., Juhel G., Auffret M. and Moraga D. 2002. Genetic and physiological responses of flounder (Platichthys flesus) populations to chemical contamination in estuaries. Environmental Toxicology and Chemistry 21 (12): 2705-2712
36. Moraga D., MdegiI-Lasram E., Romdhane M.S., El Abed A., Boutet I., Tanguy A. & Auffret M. 2002. Genetic responses to metal contamination in two clams: Ruditapes decussatus and Ruditapes philippinarum. Marine Environmental Research 54: 521-525
37. Boutet, I., Tanguy A., Auffret M., Riso R., and Moraga, D. 2002. Immunochemical quantification of metallothioneins in marine molluscs: Characterization of a metal exposure bioindicator. Environmental Toxicology and Chemistry 21 (5): 1009-1014

Contributions à ouvrages collectifs
1. Brousseau, P., Pillet, S., Frouin, H., Auffret, M., Gagné, F., Fournier, M. . 2013. Chap. 6: Linking immunotoxicity and ecotoxicological effects at higher biological levels. In: Amiard C. , Amiard J.C., Rainbow P. (eds), Ecological Biomarkers: Indicators of Ecotoxicological Effects, Boca Raton, pp. 131-154
2. Auffret M. 2005. Chapter 3: Bivalves as models for marine immunotoxicology. In Investigative immunotoxicology. H. Tryphonas, M. Fournier, B.R.Blakley, J.E.G Smits and P. Brousseau (eds). CRC Press, Boca Raton, pp. 29-48.
3. Grizel H., Besnard-Cochennec N. and Auffret M. 2003. Les types hémocytaires /The hemocytes. in Atlas d'histologie et de cytologie des Mollusques bivalves marins. H. Grizel (ed). Editions IFREMER, Plouzané, pp. 131-144.
4. Auffret M. and Oubella R. 1995. Chapter 7: Cytology and Cytometric analysis of bivalve mollusc hemocyte. in Techniques in Fish Immunology, vol. 4: Immunology and Pathology of Aquatic Invertebrates (J.S. Stolen , Fletcher T.C., Smith S.A., Zelikoff J.T., Kaatari S.L., Anderson R.S., Söderhäll K., Weeks-Perkins B.A. (eds) SOS Publications, Fair Haven, NJ, USA, pp. 55-64
5. Auffret M. and Oubella R. 1994. Cytometric parameters of bivalve molluscs: effects of environmental factors. in: Modulators of Fish Immune responses, vol. 1: Models for environmental toxicology, biomarkers, immunostimulators (J.S. Stolen and T.C. Fletcher, eds). SOS Publication, Fair Haven, pp. 23-32
6. Auffret, M. 1988. Bivalve hemocyte morphology. in : Disease processes in marine bivalve molluscs. Amer. Fish. Soc. Special Publication, 18, 169-177
7. Auffret M. 1986. Internal defence in bivalve molluscs: Ultrastructural observations on the fate of experimentally injected bacteria in Ostrea edulis granular hemocytes. in: Pathology in Marine Aquaculture. C.P. Vivarès, J. R. Bonami and E. Jaspers (eds). European Aquaculture Society, Special Publication N°9, pp. 351-356