UMR1078

UMR 1078
Génétique, génomique fonctionnelle
et biotechnologies

Publication du groupe PRIME

2018 

  • Curie A*, Friocourt G*, des Portes V, Roy A, Nazir T, Brun A, Cheylus A, Marcorelles P, Retzepi K, Maleki N, Bussy G, Paulignan Y, Reboul A, Ibarrola D, Kong J, Hadjikhani N, Laquerrière A and Gollub R. Basal ganglia involvement in ARX gene mutated patients: the reason for very specific grasping in ARX mutated patients? NeuroImage: Clinical. In press.
  • Dubos A, Meziane H, Iacono G, Curie A, Riet F, Martin C, Loaëc N, Birling MC, Selloum M, Normand E, Pavlovic G, Sorg T, Stunnenberg H, Chelly J, Humeau Y, Friocourt G*, Hérault Y* (2018). A new mouse model of ARX dup24 recapitulates the patients’ behavioral and fine motor alterations. Hum. Mol. Genet. In press.
  • De Clercq S*, Keruzore M*, Desmaris E, Pollart C, Assimacopoulos S, Preillon J, Ascenzo S, Matson CK, Lee M, Nan X, Li M, Nakagawa Y, Hochepied T, Zarkower D, Grove EA, Bellefroid EJ (2018). DMRT5 Together with DMRT3 Directly Controls Hippocampus Development and Neocortical Area Map Formation. Cereb Cortex. 28(2): 493-509.

2017 

  • Panozzo C, Laleve A, Tribouillard-Tanvier D, Ostojić J, Sellem CH, Friocourt G, Bourand-Plantefol A, Burg A, Delahodde A, Blondel M, Dujardin G (2017). Chemicals or mutations that target mitochondrial translation can rescue the respiratory deficiency of yeast bcs1 mutants. Biochim Biophys Acta Molecular Cell Research. 1864(12): 2297-2307.
  • Billant O, Blondel M, Voisset C. (2017). p53, p63 and p73 in the wonderland of S. cerevisiae. Oncotarget. 8(34): 57855-57869.
  • Lista MJ, Martins RP, Angrand G, Quillévéré A, Daskalogianni C, Voisset C, Teulade-Fichou MP, Fåhraeus R, Blondel M. (2017). A yeast model for the mechanism of the Epstein-Barr virus immune evasion identifies a new therapeutic target to interfere with the virus stealthiness. Microb Cell. 4(9): 305-307.
  • Lista MJ, Martins RP, Billant O, Contesse MA, Findakly S, Pochard P, Daskalogianni C, Beauvineau C, Guetta C, Jamin C, Teulade-Fichou MP, Fåhraeus R, Voisset C*, Blondel M* (2017). Nucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNA. Nat Commun. 8: 16043.
  • Voisset C, Blondel M, Jones GW, Friocourt G, Stahl G, Chédin S, Béringue V, Gillet R. (2017). The double life of the ribosome: When its protein folding activity supports prion propagation. Prion. 11(2): 89-97.
  • Muralidharan B, Keruzore M, Pradhan SJ, Roy B, Shetty AS, Kinare V, D'Souza L, Maheshwari U, Karmodiya K, Suresh A, Galande S, Bellefroid EJ, Tole S (2017). Dmrt5, a Novel Neurogenic Factor, Reciprocally Regulates Lhx2 to Control the Neuron-Glia Cell-Fate Switch in the Developing Hippocampus. J Neurosci. 37(46): 11245-11254.
  • Young FI, Keruzore M, Nan X, Gennet N, Bellefroid EJ, Li M (2017). The doublesex-related Dmrta2 safeguards neural progenitor maintenance involving transcriptional regulation of Hes1. Proc Natl Acad Sci USA. 114(28): E5599-E5607.

2016 

  • Mattiske T, Lee K, Gecz J, Friocourt G, Shoubridge C (2016). Embryonic forebrain transcriptome of mice with polyalanine expansion mutations in the ARX homeobox gene. Hum Mol Genet. 25(24): 5433-5443.
  • Blondel M, Soubigou F, Evrard J, Nguyen PH, Hasin N, Chédin S, Gillet R, Contesse MA, Friocourt G, Stahl G, Jones GW, Voisset C (2016). Protein Folding Activity of the Ribosome is involved in Yeast Prion Propagation. Sci Rep. 6: 32117.
  • Billant O, Léon A, Le Guellec S, Friocourt G, Blondel M, Voisset C (2016). The dominant-negative interplay between p53, p63 and p73: A family affair. Oncotarget. 7(43): 69549-69564.

2015 

  • Daskalogianni C, Pyndiah S, Apcher S, Mazars A, Manoury B, Ammari N, Nylander K, Voisset C, Blondel M, Fåhraeus R (2015). Epstein-Barr virus-encoded EBNA1 and ZEBRA: targets for therapeutic strategies against EBV-carrying cancers. J Pathol. 235(2): 334-41.
  • Lista MJ, Voisset C, Contesse MA, Friocourt G, Daskalogianni C, Bihel F, Fåhraeus R, Blondel M (2015).The long-lasting love affair between the budding yeast Saccharomyces cerevisiae and the Epstein-Barr virus. Biotechnol J. 10(11): 1670–1681.

2014 

  • Voisset C, Blondel M. (2014) Chemobiology at happy hour: yeast as a model for pharmacological screening. Med Sci (Paris). 30(12): 1161-1168.
  • Aiyar RS, Bohnert M, Duvezin-Caubet S, Voisset C, Gagneur J, Fritsch ES, Couplan E, von der Malsburg K, Funaya C, Soubigou F, Courtin F, Suresh S, Kucharczyk R, Evrard J, Antony C, St Onge RP, Blondel M, di Rago JP, van der Laan M, Steinmetz LM. (2014). Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders. Nat Commun. 5:5585.
  • Marcorelles P, Friocourt G, Uguen A, Ledé F, Férec C, Laquerrière A (2014). Cystic Fibrosis Transmembrane Conductance Regulator Protein (CFTR) Expression in the Developing Human Brain: Comparative Immunohistochemical Study between Patients with Normal and Mutated CFTR. J Histochem Cytochem. 62(11): 791-801.
  • Nguyen PH, Hammoud H, Halliez S, Pang Y, Evrard J, Schmitt M, Oumata N, Bourguignon JJ, Sanyal S, Beringue V, Blondel M, Bihel F, Voisset C. (2014). Structure-Activity Relationship Study around Guanabenz Identifies Two Derivatives Retaining Antiprion Activity but Having Lost α2-Adrenergic Receptor Agonistic Activity. ACS Chem Neurosci. 5(10): 1075-82.
  • Voisset C, Daskalogianni C, Contesse MA, Mazars A, Arbach H, Le Cann M, Soubigou F, Apcher S, Fåhraeus R, Blondel M (2014). A yeast-based assay identifies drugs that interfere with Epstein-Barr virus immune evasion. Dis Model Mech. 7: 435-444.
  • Nguyen PH, Oumata N, Soubigou F, Evrard J, Desban N, Lemoine P, Bouaziz S, Galons H, Blondel M and Voisset C (2014). Evaluation of the antiprion activity of 6-aminophenanthridines and related heterocycles. European Journal of Medicinal Chemistry. 82: 363-371
  • Voisset C, García-Rodríguez N, Birkmire A, Blondel M, Wellinger RE (2014). Using yeast to model calcium-related diseases: Example of the Hailey-Hailey disease. Biochim Biophys Acta, Molecular Cell Research 1843: 2315–2321.

2013 

  • Bellefroid EJ, Leclère L, Saulnier A, Keruzore M, Sirakov M, Vervoort M, De Clercq S (2013). Expanding roles for the evolutionarily conserved Dmrt sex transcriptional regulators during embryogenesis. Cell Mol Life Sci. 70(20): 3829-45.
  • Saulnier A*, Keruzore M*, De Clercq S, Bar I, Moers V, Magnani D, Walcher T, Filippis C, Kricha S, Parlier D, Viviani L, Matson CK, Nakagawa Y, Theil T, Götz M, Mallamaci A, Marine JC, Zarkower D, Bellefroid EJ (2013). The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals. Cereb Cortex. 23(11): 2552-67.
  • Quéméner-Redon S, Bénech C, Audebert-Bellanger S, Friocourt G, Planes M, Parent P, Férec C (2013). A small de novo 16q24.1 duplication in a woman with severe clinical features. Eur J Med Genet 56(4): 211-5.
  • Pang Y, Kurella S, Voisset C, Samanta D, Banerjee D, Schabe A, Das Gupta C, Galons H, Blondel M, Sanyal S (2013). The antiprion compound 6-aminophenanthridine inhibits the protein folding activity of the ribosome by direct competition. J Biol Chem 288(26): 19081-9.
  • Oumata N, Nguyen PH, Beringue V, Soubigou F, Pang Y, Desban N, Massacrier C, Morel Y, Paturel C, Contesse MA, Bouaziz S, Sanyal S, Galons H, Blondel M, Voisset C (2013). The Toll-Like Receptor Agonist Imiquimod Is Active against Prions. PLoS One 8(8):e72112.

2012 

  • Marcorelles P, Gillet D, Friocourt G, Ledé F, Samaison L, Huguen G and Férec C (2012). CFTR protein expression in the male excretory duct system during development. Hum Pathol 43: 390-397.

2011 

  • Reis SD, Pang Y, Vishnu N, Voisset C, Galons H, Blondel M and Sanyal S (2011). Mode of action of the antiprion drugs 6AP and GA on ribosome assisted protein folding. Biochimie 93: 1047-1054.
  • Voisset C, Saupe SJ and Blondel M (2011). The various facets of the protein-folding activity of the ribosome. Biotechnol J 6: 668-673.
  • Barbezier N, Chartier A, Bidet Y, Buttstedt A, Voisset C, Galons H, Blondel M, Schwarz E and Simonelig M (2011). Antiprion drugs 6-aminophenanthridine and guanabenz reduce PABPN1 toxicity and aggregation in oculopharyngeal muscular dystrophy. EMBO Mol Med 3: 35-49.
  • Quillé ML, Carat S, Quéméner-Redon S, Hirchaud E, Baron D, Benech C, Guihot J, Placet M, Mignen O, Férec C, Houlgatte R and Friocourt G (2011). High-throughput analysis of promoter occupancy reveals new targets for Arx, a gene mutated in mental retardation and interneuronopathies. PLoS One 6: e25181.
  • Friocourt G, Marcorelles P, Saugier-Veber P, Quille ML, Marret S and Laquerrière A (2011). Role of cytoskeletal abnormalities in the neuropathology and pathophysiology of type I lissencephaly. Acta Neuropathol 121: 149-170.
  • Friocourt G and Parnavelas JG (2011). Identification of Arx targets unveils new candidates for controlling cortical interneuron migration and differentiation. Front Cell Neurosci 5: 28.
  • Ghimouz R, Bar I, Hanotel J, Minela B, Keruzore M, Thelie A, Bellefroid EJ (2011). The homeobox leucine zipper gene Homez plays a role in Xenopus laevis neurogenesis. Biochem Biophys Res Commun.415(1): 11-6.

2010 

  • Gug F, Oumata N, Tribouillard-Tanvier D, Voisset C, Desban N, Bach S, Blondel M, and Galons H (2010). Synthesis of conjugates of 6-aminophenanthridine and guanabenz, two structurally unrelated prion inhibitors, for the determination of their cellular targets by affinity chromatography. Bioconjug Chem 21: 279-288.
  • Lecourtois M, Poirier K, Friocourt G, Jaglin X, Goldenberg A, Saugier-Veber P, Chelly J and Laquerrière A. (2010). Human lissencephaly with cerebellar hypoplasia due to mutations in TUBA1A: expansion of the foetal neuropathological phenotype. Acta Neuropathol 119: 779-789.
  • Marcorelles P, Laquerrière A, Adde-Michel C, Marret S, Saugier-Veber P, Beldjord C and Friocourt G (2010). Evidence for tangential migration disturbances in human lissencephaly resulting from a defect in LIS1, DCX and ARX genes. Acta Neuropathol 120: 503-515.
  • Friocourt G and Parnavelas JG. (2010). Mutations in ARX result in several defects involving GABAergic neurons. Front Cell Neurosci 4: 4.

2009 

  • Voisset C, Saupe S and Blondel M (2009). Procedure for identification and characterization of drugs efficient against mammalian prion: from a yeast-based antiprion drug screening assay to in vivo mouse models. Infectious Diseases, Drug Targets 9: 31-39.

2008 

  • Tribouillard-Tanvier D, Beringue V, Desban N, Gug F, Bach S, Voisset C, Galons H, Laude H, Vilette D and Blondel M. (2008). Antihypertensive drug guanabenz is active in vivo against both yeast and mammalian prions. PLoS One 3: e1981.
  • Tribouillard-Tanvier D, Dos Reis S, Gug F, Voisset C, Beringue V, Sabate R, Kikovska E, Talarek N, Bach S, Huang C, Desban N, Saupe SJ, Supattapone S, Thuret JY, Chedin S, Vilette D, Galons H, Sanyal S and Blondel M (2008). Protein folding activity of ribosomal RNA is a selective target of two unrelated antiprion drugs. PLoS One 3: e2174.
  • Voisset C, Thuret JY, Tribouillard-Tanvier D, Saupe SJ and Blondel M (2008). Tools for the study of ribosome-borne protein folding activity. Biotechnol J 3: 1033-1040.
  • Voisset C, Lavie M, Helle F, Op De Beeck A, Bilheu A, Bertrand-Michel J, Tercé F, Cocquerel L, Wychowski C, Vu-Dac N and Dubuisson J (2008). Ceramide enrichment of the plasma membrane induces CD81 internalization and inhibits hepatitis C virus entry. Cell Microbiol 10: 606-617.
  • Voisset C, Weiss RA and Griffiths DJ (2008). Human RNA "rumor" viruses: the search for novel human retroviruses in chronic disease. Microbiol Mol Biol Rev 72: 157-196.
  • Friocourt G, Kanatani S, Tabata H, Yozu M, Takahashi T, Antypa M, Raguénès O, Chelly J, Férec C, Nakajima K, Parnavelas JG (2008). Cell-autonomous roles of ARX in cell proliferation and neuronal migration during corticogenesis. J Neurosci 28: 5794-5805.

2007 

  • Helle F, Goffard A, Morel V, Duverlie G, McKeating J, Keck ZY, Foung S, Penin F, Dubuisson J and Voisset C (2007). The neutralizing activity of anti-hepatitis C virus antibodies is modulated by specific glycans on the E2 envelope protein. J Virol 81: 8101-8111.
  • Johansson DX, Voisset C, Tarr AW, Aung M, Ball JK, Dubuisson J and Persson MA (2007). Human combinatorial libraries yield rare antibodies that broadly neutralize hepatitis C virus. Proc Natl Acad Sci USA 104: 16269-16274.
  • Friocourt G, Liu J, Antypa M, Rakic S, Walsh CA and Parnavelas JG (2007). Both Doublecortin and Doublecortin-like kinase play a role in cortical interneuron migration. J Neurosci 27: 3875-3883.
  • Trouvé P, Le Drévo MA, Kerbiriou M, Friocourt G, Fichou Y, Gillet D, Férec C (2007). Annexin V interacts with cystic fibrosis transmembrane conductance regulator. Biochim Biophys Acta 1772: 1121-1133.
  • Friocourt G (2007). From genes to human diseases in cortical development. Bioessays 29: 706-709.

2006 

  • Cocquerel L, Voisset C and Dubuisson J (2006). Hepatitis C virus entry: potential receptors and their biological functions. J Gen Virol 87: 1075-1084.
  • Dreux M, Pietschmann T, Granier C, Voisset C, Ricard-Blum S, Mangeot PE, Keck Z, Foung S, Vu-Dac N, Dubuisson J, Bartenschlager R, Lavillette D and Cosset FL (2006). High density lipoprotein inhibits hepatitis C virus-neutralizing antibodies by stimulating cell entry via activation of the scavenger receptor BI. J Biol Chem 281: 18285-18295.
  • Helle F, Wychowski C, Vu-Dac N, Gustafson KR, Voisset C and Dubuisson J (2006). Cyanovirin-N inhibits hepatitis C virus entry by binding to envelope protein glycans. J Biol Chem 281: 25177-25183.
  • Lavie M, Voisset C, Vu-Dac N, Zurawski V, Duverlie G, Wychowski C and Dubuisson J (2006). Serum amyloid A has antiviral activity against hepatitis C virus by inhibiting virus entry in a cell culture system. Hepatology 44: 1626-1634.
  • Rouille Y, Helle F, Delgrange D, Roingeard P, Voisset C, Blanchard E, Belouzard S, McKeating J, Patel AH, Maertens G, Wakita T, Wychowski C and Dubuisson J (2006). Subcellular localization of hepatitis C virus structural proteins in a cell culture system that efficiently replicates the virus. J Virol 80: 2832-2841.
  • Voisset C, Op De Beeck A, Horellou P, Dreux M, Gustot T., Duverlie, G., Cosset, F.L., Vu-Dac, N., and Dubuisson, J. (2006). High-density lipoproteins reduce the neutralizing effect of hepatitis C virus (HCV)-infected patient antibodies by promoting HCV entry. J Gen Virol 87, 2577-2581.
  • Friocourt G, Poirier K, Rakic S, Parnavelas JG and Chelly J. (2006). The role of ARX in brain development. Eur. J. Neurosci. 23, 869-876.

2005 

  • Voisset C, Callens N, Blanchard E, Op De Beeck A, Dubuisson J, Vu-Dac N. (2005). High density lipoproteins facilitate hepatitis C virus entry through the scavenger receptor class B type I. J Biol Chem 280: 7793-7799
  • Lavillette D, Tarr AW, Voisset C, Donot P, Bartosch B, Bain C, Patel AH, Dubuisson J, Ball JK, Cosset FL. (2005). Characterization of host-range and cell entry properties of the major genotypes and subtypes of hepatitis C virus. Hepatology 41: 265-274.
  • Friocourt G, Kappeler C, Saillour Y, Fauchereau F, Rodriguez MS, Bahi N, Vinet MC, Chafey P, Poirier K, Taya, S, Wood, SA, Dargemont C, Francis F and Chelly J. (2005) Doublecortin interacts with the ubiquitin protease DFFRX, which associates with microtubules in neuronal processes. Mol Cell Neurosci 28: 153-164.

2004 

  • Voisset C and Dubuisson J. (2004). Functional hepatitis C virus envelope glycoproteins. Biol Cell 96: 413-20.
  • Op De Beeck A, Voisset C, Bartosch B, Ciczora Y, Cocquerel L, Keck Z, Foung S, Cosset FL and Dubuisson J. (2004). Characterization of Functional Hepatitis C Virus Envelope Glycoproteins. J Virol 78: 2994-3002.
  • Poirier K, Van Esch H, Friocourt G, Saillour Y, Bahi N, Backer S, Souil E, Castelnau-Ptakhine L, Beldjord C, Francis F, Bienvenu T and Chelly J (2004). Neuroanatomical distribution of ARX in brain and its localisation in GABAergic neurons. Mol Brain Res 122: 35-46.

2003 

  • Voisset C., Myers RE, Carne A, Kellam P and Griffiths DJ (2003). Rabbit endogenous retrovirus-H encodes a functional protease. J Gen Virol 84: 215-225.
  • Bahi N, Friocourt G, Carrié A, Graham ME, Weiss JL, Chafey P, Fauchereau F, Burgoyne RD and Chelly J (2003). IL1 receptor accessory protein like, a protein involved in X-linked mental retardation, interacts with Neuronal Calcium Sensor-1 and regulates exocytosis. Hum Mol Genet 12: 1415-25.
  • Friocourt G, Koulakoff A, Chafey P, Boucher D, Fauchereau F, Chelly J and Francis F (2003). Doublecortin functions at the extremities of growing neuronal processes. Cereb Cortex 13: 620-626.

2002 

  • Griffiths DJ, Voisset C, Venables PJW and Weiss RA (2002). A novel endogenous retrovirus in rabbits previously reported as human retrovirus 5. J Virol 76: 7094-7102.
  • Bienvenu T, Poirier K, Friocourt G, Bahi N, Beaumont D, Fauchereau F, Ben Jeema L, Zemni R, Vinet MC, Francis F, Couvert P, Gomot M, Moraine C, van Bokhoven H, Kalscheuer V, Frints S, Gecz J, Ohzaki K, Chaabouni H, Fryns JP, Des Portes V, Beldjord C, and Chelly J (2002). ARX, a novel Prd-class-homeobox gene highly expressed in the telencephalon, is mutated in X-linked mental retardation. Hum Mol Genet 11: 981-991.
  • Benchoua A, Couriaud C, Guegan C, Tartier L, Couvert P, Friocourt G, Chelly J, Menissier-De Murcia J and Onteniente B. (2002). Active caspase-8 translocates into the nucleus of apoptotic cells to inactivate poly(ADP-ribose) polymerase-2. J Biol Chem 277: 34217-22.

2001 

  • Voisset C, Tönjes RR, Breyton P, Mandrand B and Paranhos-Baccalà G (2001). Specific detection of RT activity in culture supernatants of retrovirus-producing cells using synthetic DNA as competitor in polymerase enhanced reverse transcriptase assay. J Virol Methods 94: 187-193.
  • Bordet T, Castelnau-Ptakhine L, Fauchereau F, Friocourt G, Kahn A and Haase G. (2001). Neuronal targeting of cardiotrophin-1 by coupling with tetanus toxin C fragment. Mol Cell Neurosci 17: 842-854.
  • Friocourt G, Chafey P, Billuart P, Koulakoff A, Vinet MC, Schaar BT, McConnell SK, Francis F and Chelly J. (2001). Doublecortin interacts with µ Subunits of clathrin adaptor complexes in the developing nervous system. Mol Cell Neurosci 18: 307-319.

2000 

  • Voisset C, Bouton O, Bedin F, Duret L, Mandrand B, Mallet F, Paranhos-Baccalà G (2000). Chromosomal distribution and coding capacity of the human endogenous retrovirus HERV-W family. AIDS Res Hum Retroviruses 16: 731-740.
  • Voisset C, Mandrand B and Paranhos-Baccalà G (2000). RNA amplification technique, NASBA, also amplifies homologous plasmid DNA in non-denaturing conditions. Biotechniques 29: 236-238.
  • Zemni R, Bienvenu T, Vinet MC, Sefiani A, Carrie A, Billuart P, McDonell N, Couvert P, Francis F, Chafey P, Fauchereau F, Friocourt G, Des Portes V, Cardona A, Frints S, Meindl A, Brandau O, Ronce N, Moraine C, van Bokhoven H, Ropers HH, Sudbrak R, Kahn A, Fryns JP, Beldjord C and Chelly J. (2000). A new gene involved in X-linked mental retardation identified by analysis of an X;2 balanced translocation. Nat Genet 24: 167-170.

1999 

  • Voisset C, Blancher A, Perron H, Mandrand B, Mallet F and Paranhos-Baccalà G (1999). Phylogeny of a novel family of human endogenous retrovirus sequences, HERV-W, in humans and other primates. AIDS Res Hum Retroviruses 15: 1529-1533.
  • Elaissari A, Holt L, Meunier F, Voisset C, Pichot C, Mandrand B and Mabilat C (1999). Hydrophilic and cationic latex particles for the specific extraction of nucleic acids. J Biomater Sci Polym Ed 10: 403-420.
  • Francis F, Koulakoff A, Boucher D, Chafey P, Schaar B, Vinet MC, Friocourt G, McDonnell N, Reiner O, Kahn A, McConnell SK, Berwald-Netter Y, Denoulet P and Chelly J. (1999). Doublecortin is a developmentally regulated microtubule-associated protein expressed in migrating and differentiating neurons. Neuron 23: 247-256.

1997 

  • Perron H, Garson JA, Bedin F, Beseme F, Paranhos-Baccalà G, Komurian-Pradel F, Mallet F, Tuke P.W., Voisset C., Blond J.L., Lalande B., Seigneurin J.M., Mandrand B (1997). Molecular identification of a novel retrovirus repeatedly isolated from patients with multiple sclerosis. The Collaborative Research Group on Multiple Sclerosis. Proc Natl Acad Sci USA 94: 7583-7588.