Pierre Lafère

Pierre Lafère

Professeur des Universités (ULB)
Praticien hospitalier en Anesthésie-Réanimation
pierre.lafere@univ-brest.fr

Plongée sous-marine, Médecine hyperbare, Effets des variations de l’oxygène sur les fonctions physiologiques (transcription, physiologie vasculaire, homéostasie cellulaire), Alternatives à la transfusion, Gestion de la douleur postopératoire. 

Projet FRHE 2021-2022, Fédération Wallonie-Bruxelles : « Utilisation des variations d’oxygène comme un stimulus d’adaptation des voies métaboliques » (DELTOX)

Programme Marie Curie Initial Training Network (FP7-PEOPLE-ITN-2010 n°264816) : « Physiopathology of decompression: risk factors for bubble formation and decompression sickness » (PHYPODE).

C. LEVEQUE, S. MRAKIC SPOSTA, S. THEUNISSEN, P. GERMONPRÉ, K. LAMBRECHTS, SA. VEZZOLI, M. GUSSONI, M. LEVENEZ, P. LAFÈRE, F. GUERRERO, C. BALESTRA. (2023) Oxidative Stress Response's Kinetics after 60 Minutes at Different (1.4 ATA and 2.5 ATA) Hyperbaric Hyperoxia Exposures. Int J Mol Sci;24 (15):12361.

 

C. LEVEQUE, S. MRAKIC SPOSTA, S. THEUNISSEN, P. GERMONPRÉ, K. LAMBRECHTS, SA. VEZZOLI, G. BOSCO, M. LEVENEZ, P. LAFÈRE, F. GUERRERO, C. BALESTRA. (2023) Oxidative Stress Response Kinetics after 60 Minutes at Different Levels (10% or 15%) of Normobaric Hypoxia Exposure. Int J Mol Sci;24(12):10188.

 

C. LEVEQUE, S. MRAKIC SPOSTA, P. LAFÈRE, SA. VEZZOLI, P. GERMONPRÉ, A. BEER, S. MIEVIS, F. VIRGILI, K. LAMBRECHTS, S. THEUNISSEN, F. GUERRERO, C. BALESTRA. (2023) Oxidative Stress Response's Kinetics after 60 Minutes at Different (30% or 100%) Normobaric Hyperoxia Exposures. Int J Mol Sci;24(1):664.

 

C. BALESTRA, AK. ARYA, C. LEVEQUE, F. VIRGILI, P. GERMONPRÉ, K. LAMBRECHTS, P. LAFÈRE, S. THOM. (2022) Varying Oxygen Partial Pressure Elicits Blood-Borne Microparticles Expressing Different Cell-Specific Proteins-Toward a Targeted Use of Oxygen? Int J Mol Sci; 23(14):7888.

 

M. LEVENEZ, K. LAMBRECHTS, S. MRAKIC SPOSTA, A. VEZZOLI, P. GERMONPRÉ, H. PIQUE, F. VIRGILI, G. BOSCO, P. LAFÈRE, C. BALESTRA. (2022) Can full-face mask use during SCUBA diving counteract related oxidative stress and endothelial dysfunction. Int J Environ Res Public Health;19(2):965.

 

C. BALESTRA, K. LAMBRECHTS, S. MRAKIC-SPOSTA, A. VEZZOLI, M. LEVENEZ, P. GERMONPRÉ, F. VIRGILI, G. BOSCO, P. LAFÈRE. (2021) Hypoxic and Hyperoxic Breathing as a Complement to Low-Intensity Physical Exercise Programs: A Proof-of-Principle Study. Int J Mol Sci; 22(17):9600.

 

P. LAFÈRE, K. LAMBRECHTS, P. GERMONPRÉ, A. BALESTRA, F.L. GERMONPRÉ, A. MARRONI, D. CIALONI, G. BOSCO, C. BALESTRA. (2021) Heart Rate Variability during a standard dive: a role for inspired oxygen pressure? Front Physiol; 12:635132

 

D. FRATANTONIO, F. VIRGILI, A. ZUCCHI, K. LAMBRECHTS, T. LATRONICO, P. GERMONPRÉ, P. LAFÈRE, C. BALESTRA. (2021) Increasing oxygen partial pressures induce a distinct transcriptional response in human PBMC: A pilot study on the “Normobaric Oxygen Paradox”. Int J Mol Sci; 22(1):458.

 

P. LAFÈRE, W. HEMELRYCK, P. GERMONPRÉ, L. MATITY, F. GUERRERO, C. BALESTRA. (2019) Early detection of diving-related cognitive impairment of different nitrogen-oxygen gas mixtures using critical flicker fusion frequency. Diving Hyperb Med; 49(2): 120-7

 

P. GERMONPRÉ, C. BALESTRA, W. HEMELRYCK, P. BUZZACOTT, P. LAFÈRE. (2017) Objective versus subjective evaluation of performance during 0.4MPa dives breathing air or Nitrox.  Aerosp Med Hum Perform; 88(5): 469-75.

 

W. HEMELRYCK, M. ROZLOZNIK, P. GERMONPRÉ, C. BALESTRA, P. LAFÈRE. (2013) Functional comparison between Critical Flicker Fusion Frequency and simple cognitive tests in subjects breathing air or oxygen in normobaric condition. Diving Hyperb Med; 43(2): 114-8.

 

P. LAFÈRE, T. SCHUBERT, D. DE BELS, P. GERMONPRÉ, C. BALESTRA. (2013) Can the Normobaric Oxygen Paradox (NOP) increase reticulocyte count after traumatic hip surgery? J Clin Anesth; 25(2): 129-34.

 

S. THEUNISSEN, D. DE BELS, J. DEVRIENDT, P. GERMONPRÉ, P. LAFÈRE, J. VALSAMIS, T. SNOECK, P. MEEUS, C. BALESTRA. (2011) The normobaric oxygen paradox: does it increase haemoglobin? Crit Care; 15(Suppl 1): 422.

 

C. BALESTRA, P. GERMONPRÉ, P. LAFÈRE, Y. CICCARELLA, P. VAN DER LINDEN. (2010) The Normobaric Oxygen paradox: a simple way to induce endogenous erythropoietin production and concomitantly raise hemoglobin levels in anemic patients. Transfusion Alternative in Transfusion Medicine; 11 (1): 39-42.