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  • Chevet B, Devauchelle-Pensec V, Pontarini E, Baloche V, Bombardieri M, Bowman SJ, Barnes M, Sreih AG, Liu J, Kelly S, Christodoulou A, Moingeon P, Laigle L, Soret P, Le Dantec C, Pers JO, Alarcon-Riquelme ME, Barturen G, Mariette X, van Roon J, Seror R, Nocturne G, Cornec D, Foulquier N, PRECISEADS Clinical Consortium, NECESSITY consortium. Transcriptomic stratification predicts response to rituximab, abatacept, or the association of hydroxychloroquine and leflunomide in 3 randomised controlled clinical trials of Sjögren’s disease. Ann Rheum Dis. 2025 Dec 24;S0003-4967(25)04549–2. PMID: 41448992
     
  • Gandubert C, Höllerer S, Sériau L, Garaud S, le Dantec C, Devauchelle-Pensec V, Hillion S, Cornec D, Frutoso M. Single-Cell Spatial Transcriptomic of Sjögren’s Disease Salivary Glands. Methods Mol Biol. 2026;2990:179–206. PMID: 41269557
     
  • Chevet B, Devauchelle-Pensec V. Tapering or stopping tocilizumab in PMR: toward optimized treatment withdrawal. Joint Bone Spine. 2025 Dec 18;106016. PMID: 41421728
     
  • Nicol S, Trin K, Simon LA, Nowak E, Duval O, Martin C, Abdelouahad S, Lengagne S, Chinchilla V, Gilet V, Briantais A, Saraux A, Cornec D, De Moreuil C, Tanguy ML, Guellec D. Evaluation of a nurse-led program for the prevention of complications of long-term glucocorticoids (COCORTICO): study protocol for a randomized trial. Trials. 2025 Nov 17;26(1):510. PMCID: PMC12625073
     
  • Hamroun S, de Frémont GM, Costedoat-Chalumeau N, Couderc M, Flipo RM, Sellam J, Richez C, Belkhir R, Gossec L, Marotte H, Dernis E, Frazier-Mironer A, Gervais E, Lukas C, Devauchelle-Pensec V, Deroux A, Guern VL, Guettrot-Imbert G, Lelong N, Pannier E, Sentilhes L, Ray CL, Seror R, Molto A, GR2 and the ENP2021 Study Groups. Evaluation of pregnancy outcomes in patients with spondyloarthritis compared to the general population: results from a French national prospective and matched study. Ann Rheum Dis. 2025 Nov 14;S0003-4967(25)04511-X. PMID: 41241656

The UMR1227 'B Lymphocytes and Autoimmunity' brings together several clinical entities around the immunology laboratory.

Rheumatology, haematology, nephorology and odontology for a scientific project articulated around two main complementary and interconnected axes: an axis dedicated to the understanding of the mechanisms that govern the functional orientation of B cells in autoimmunity, and a translational axis aiming at developing new tools to improve the efficiency of B-cell targeting immunotherapies, while working on a better stratification of patients, a better understanding of the mode of action of these therapies, and the development of these therapies and innovative therapeutic strategies.

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