Mise à jour le   15/12/2023
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Chimie Organique               Application Santé         Application Matériaux ou Coordination    


A new series of magnetic and luminescent layered hybrid materials obtained from thianthrene phosphonic acid: M(H2O)PO3-S2C12H7 (M = Cu, Zn) and M(H2O)2(PO2OH-S2C12H7)2 (M = Mn, Co)
Geoffrey Letheux, Parameshwari Ganesan, Fabien Veillon, Julien Varignon, Olivier Perez, Julien Cardin,  Christophe Labbé, Guillaume Rogez, Mathilde Ligeour, Paul-Alain Jaffrès, Jean-Michel Rueff
Dalton Trans, 2023, 52, 18362-18379 ; DOI: 10.1039/d3dt03153e


 Synthesis of Ether lipids: natural compounds and analogues
M.A.G.B. Gomes, A. Bauduin, C. Le Roux, R. Fouinneteau, W. Berthe, M. Berchel, H. Couthon, P.A. Jaffrès
Beilstein J. Org. Chem. 2023, 19, 1299-1369  ; DOI: 10.3762/bjoc.19.96  


 Evaluation of lipophosphoramidates-based amphiphilic compounds on the formation of biofilms of marine bacteria
Dorsaf Malouch, Mathieu Berchel, Catherine Dreanno, Sabine Stachowski-Haberkornc, Morgane Chalopin, Yoann Godfrin, Paul-Alain Jaffrès
Biofouling, 2023,  39, 591-605, DOI: 10.1080/08927014.2023.2241377


 H3nota Derivatives Possessing Picolyl and Picolinate Pendants for Ga3+ Coordination and 67Ga3+ Radiolabeling
Axia Marlin, Angus Koller, Enikö Madarasi, Marie Cordier, David Esteban-Gómez, Carlos Platas-Iglesias, Gyula Tircsó, Eszter Boros, Véronique Patinec, and Raphaël Tripier
Inorg. Chem. 2023, DOI: 10.1021/acs.inorgchem.3c01417


  Preclinical Evaluation of a 64Cu-Based Theranostic Approach in a Murine Model of Multiple Myeloma
Cassandra Métivier, Patricia Le Saëc, Joëlle Gaschet, Catherine Chauvet, Séverine Marionneau-Lambot, Peter O. Hofgaard, Bjarne Bogen, Julie Pineau, Nathalie Le Bris, Raphaël Tripier, Cyrille Alliot, Férid Haddad, Michel Chérel, Nicolas Chouin, Alain Faivre-Chauvet, and Latifa Rbah-Vidal.
Pharmaceutics., 2023, 15(7), 1817, DOI: 10.3390/pharmaceutics15071817.


 Design of Bifunctional Pyclen-Based Lanthanide Luminescent Bioprobes for Targeted Two-Photon Imaging
Nadège Hamon, Lucile Bridou, Margaux Roux, Olivier Maury, Raphaël Tripier*, and Maryline Beyler*
J. Org. Chem. 2023, DOI: 10.1021/acs.joc.3c00287


 A Phosphine Oxide-Functionalized Cyclam as a Specific Copper(II) Chelator
Le Roy, Marie M.; Hery, Simon; Saffon-Merceron, Nathalie; Platas-Iglesias, Carlos; Troadec, Thibault; Tripier, Raphael
Inorganic Chemistry, 2023, 62, 21, 8112-8122, DOI: 10.1021/acs.inorgchem.3c00329


 Highly inert Cu(ii) complexes of C-aryl bifunctional cyclam-picolinates with remarkable 64Cu-labelling and biodistribution
Pineau, Julie; Lima, Luis M. P.; Le Roy, Marie M.; Marionneau-Lambot, Severine; Cordier, Marie; Le Saec, Patricia; Zeevaart, Jan Rijn; Driver, Cathryn H. S.; Faivre-Chauvet, Alain; Le Bris, Nathalie; et al
Chem. Commun., 2023, 59, 888-891, DOI: 10.1039/D2CC06602E


 Gene transfection using branched cationic amphiphilic compounds for an aerosol administration in cystic fibrosis context
Rosy Ghanem, Mathieu Berchel, Tanguy Haute, Xavier Buin, Véronique Laurent, Raphaëlle Youf, Amal Bouraoui, Tony Le Gall, Paul-Alain Jaffrès, Tristan Montier
Int. J. Pharm., 2023, 631, 122491; DOI: 10.1016/j.ijpharm.2022.122491


 On the dissociation pathways of copper complexes relevant as PET imaging agents
Rocío Uzal-Varela, Véronique Patinec, Raphaël Tripier, Laura Valencia, Marcelino Maneiro, Moisés Canle, Carlos Platas-Iglesias, David Esteban-Gómez, Emilia Iglesias
J. Inorg. Biochem. 2022, 236,11951, DOI: 10.1016/j.jinorgbio.2022.111951, hal-03765239


 Relevance of Palladium to Radiopharmaceutical Development Considering Enhanced Coordination Properties of TE1PA
Julie Pineau, Dr. Luís M. P. Lima, Prof. Carlos Platas‐Iglesias, Prof. Jan Rijn Zeevaart, Dr. Cathryn H. S. Driver, Dr. Nathalie Le Bris, and Prof. Raphaël
Chemistry. 2022 Jul 20; 28(41): e202200942, DOI: 10.1002/chem.202200942, hal-03697874, version 1


 New Triazacycloalkane Derivatives as Cytotoxic Agents for CLL Treatment: From Proof of Concept to the Targeting Biomolecule
Axia Marlin, Fiona Le Pape, Jocelyn Le Goff, Nadège Hamon, Thibault Troadec, Raphaël Tripier, Christian Berthou, and Véronique Patinec
Bioconjugate Chem., 2022, asap article, DOI: 10.1021/acs.bioconjchem.2c00227, hal-03697659


 Bioconjugated chelates based on (methylpyridinyl)tacn: synthesis, 64Cu labeling and in vitro evaluation for prostate cancer targeting.
A. Marlin, I. Hierlmeier, A. Guillou, M. Bartholomä, R. Tripier, V. Patinec,
Metallomics., 2022, asap article, DOI: 10.1093/mtomcs/mfac036, hal-03697656 


 Copper(II) and Zinc(II) Complexation with N Ethylene hydroxycyclams and Consequences on the Macrocyclic Backbone Configuration
Nancy AlHaddad,   Evan Lelong,   Jong-Min Suh,   Marie Cordier,   Mi Hee Lim,   Guy Royal,   Carlos Platas-Iglesias,   Hélène Bernard  and  Raphaël Tripier
Dalton Trans., 2022, DOI: 10.1039/D2DT00941B, hal-03679754, v1


 Electrocatalytic reduction of CO2 in water by a C-functionalized Ni-cyclam complex grafted onto carbon
Forget, Amélie; Regnacq, Matthieu; Orain, Christophe; Touzé, Ewen; Lelong, Evan; Brandily, Christophe; Bernard, Hélène; Tripier, Raphaël and Le Poul, Nicolas.
Chem. Commun. 2022, DOI: 10.1039/D2CC01667B, Hal-03679753, v1


 Development of a High-Performance Thin-Layer Chromatography Method for the Quantification of Alkyl
Glycerolipids and Alkenyl Glycerolipids from Shark and Chimera Oils and Tissues

Marion Papin, Cyrille Guimaraes, Benoit Pierre-Aue, Delphine Fontaine, Jeoffrey Pardessus,
Hélène Couthon, Gaëlle Fromont, Karine Mahéo, Aurélie Chantôme, Christophe Vandier and Michelle Pinault
Mar. Drugs 2022, 20(4), 270; DOI: 10.3390/md20040270


 Palladium(II) Coordination with Polyazacycloalkanes
Nathalie Le Bris*, Julie Pineau, Luís M. P. Lima and Raphaël Tripier*
Coord. Chem. Rev. 455, 2022, 214343, DOI: 10.1016/j.ccr.2021.214343, hal-03512108



 Phosphonodithioester–Amine Coupling as a Key Reaction Step for the Design of Cationic Amphiphiles Used for Gene Delivery
M. Khalil, A. Hocquigny, M. Berchel, T. Montier, P.A. Jaffrès
Molecules, 2021, 26, 7507, DOI: 10.3390/molecules26247507, Hal-03282994.


 Tuning the lipophilic nature of pyclen-based 90Y3+ radiopharmaceuticals for β-radiotherapy
Mariane Le Fur, Olivier Fougère, Nicolas Lepareur, Olivier Rousseaux, Raphaël Tripier, Maryline Beyler
Metallomics, 2021, ASAP, DOI: 10.1093/mtomcs/mfab070, hal-03468303


Fully automated 68Ga-labelling and purification of macroaggregated albumin particles for lung perfusion PET imaging
Frédérique Blanc-Béguin, Julien Masset, Philippe Robin, Raphael Tripier, Simon Hennebicq, Valérie Guilloux, Charles Vriamont, Corentin Warnier, Virginie Cogulet, Peter Eu, Pierre-Yves Salaün and Pierre-Yves Le Roux
Front. Nuc. Med. 2021, doi: 10.3389/fnume.2021.778191  


A roadmap towards pollution prevention and sustainable development of Gadolinium
Julien Ognard, Jean-Alix Barrat, François Cotton, Asim Mian, Stéphane Kremer, Yih Yian Sitoh, Sébastien Verclytte, Romaric Loffroy, Raphaël Tripier, Zarrin Alavi, Douraied Ben Salem 
J. of Neuroradiology. 2021, 409-411,


  Complexation of C-Functionalized Cyclams with Copper(II) and Zinc(II): Similarities and Changes When Compared to Parent Cyclam Analogues.
Evan Lelong, Jong-Min Suh, Gunhee Kim, David Esteban Gòmez, Marie Cordier, Mi Hee Lim, Rita Delgado, Guy Royal, Carlos Platas-Iglesias,* Hélène Bernard and Raphaël Tripier*
Inorg. Chem. 2021, 60, 15, 10857–10872, DOI: 10.1021/acs.inorgchem.1c01572, hal-03320076.



 Phosphonodithioester-Amine Coupling in water: A fast reaction to modify the surface of liposomes.
Montassar Khalil, Dany Jeanne Dit Fouque, Mathieu Berchel, Aurore Fraix, Aurélien Dupont, Salvatore Sortino, Antony Memboeuf and Paul-Alain Jaffrès Org. Biomol. Chem., 2021, 19, ; DOI:10.1039/D1OB01078F, hal-03282994


Synthetic alkyl-ether-lipid promotes TRPV2 channel trafficking trough PI3K/Akt-girdin axis in cancer cells and increases mammary tumour volume
M. Guéguinou ; R. Felix; S. Marionneau Lamboth ; T. Oullierg ; A. Penna ; S. Kouba ; A. Gambade ; Y. Fourbon ; D. Ternant ; C. Arnoult; G. Simon ; A-M. Bouchet ; A. Chantôme ; T. Harnois ; J-P. Haelters ; PA. Jaffrès ; G. Weber ; P. Bougnoux ; F. Carreaux ; O. Mignen ; C. Vandier ; M. Potier-Cartereau
Cell Calcium,97, 2021, 102435, DOI: 10.1016/j.ceca.2021.102435


Thio-ether functionalized glycolipid amphiphilic compounds reveal a potent activator of SK3 channel with vasorelaxation effect.
C. M. Sevrain; A. Bauduin; H. Couthon; PA. Jaffres; D. Fontaine; M. Gueguinou; A. Chantome; K. Maheo; C. Vandier; L. Zhang Bei; C. Pasqualin; V. Maupoil.
Org. Biomol. Chem., 2021, 19, 2753-2766 , DOI: 10.1039/D1OB00021G, hal-03187829.


Design of Polyazamacrocyclic Gd3+ Theranostic Agents Combining Magnetic Resonance Imaging and Two-Photon Photodynamic Therapy
Laura Abad Galán, Nadège Hamon, Christophe Nguyen, Enikő Molnár, János Kiss, Jonathan Mendy, Kamel Hadj-Kaddour, Mélanie Onofre, György Trencsényi, Cyrille Monnereau, Maryline Beyler, Gyula Tircsó, Magali Gary-Bobo, Olivier Maury, Raphaël Tripier
Inorg. Chem. Front., 2021,8, 2213-2224 , DOI: 10.1039/D0QI01519A, hal-03137794.


Cyclam-Based Chelators Bearing Phosphonated Pyridine Pendants for 64Cu-PET Imaging: Synthesis, Physicochemical Studies, Radiolabeling, and Bioimaging.
Richard C. Knighton, Thibault Troadec*, Valérie Mazan, Patricia Le Saëc, Séverine Marionneau-Lambot, Thomas Le Bihan, Nathalie Saffon-Merceron, Nathalie Le Bris, Michel Chérel, Alain Faivre-Chauvet, Mourad Elhabiri, Loïc J. Charbonnière, and Raphaël Tripier*
Inorg. Chem. 2021, 60, 4, 2634–2648, DOI: 10.1021/acs.inorgchem.0c03492, hal-03123032.


Pyclen-Based Ligands Bearing Pendant Picolinate Arms for Gadolinium Complexation.
Gwladys Nizou, EnikőMolnár, Nadège Hamon, Ferenc Krisztián Kálmán, Olivier Fougère, Olivier Rousseaux, David Esteban-Gòmez, Carlos Platas-Iglesias, Maryline Beyler, Gyula Tircsó and Raphaël Tripier
Inorg. Chem. 2021, 60, 4, 2390–2405, DOI: 10.1021/acs.inorgchem.0c03277, hal-03122227.


Complexation of Mn(II) by Rigid Pyclen Diacetates: Equilibrium, Kinetic, Relaxometric, Density Functional Theory, and Superoxide Dismutase Activity Studies
Zoltán Garda, Enikő Molnár, Nadège Hamon, José Luis Barriada, David Esteban-Gómez, Balázs Váradi, Viktória Nagy, Kristof Pota, Ferenc Krisztián Kálmán, Imre Tóth, Norbert Lihi, Carlos Platas-Iglesias, Éva Tóth, Raphaël Tripier and Gyula Tircso
Inorg. Chem. 2021, 60, 2, 1133–1148 DOI: 10.1021/acs.inorgchem.0c03276, hal-03094039


Development of pyrene-based fluorescent ether lipid as inhibitor of SK3 ion channels
Bauduin, A.; Papin, M.; Chantôme, A.; Couthon, H.; Deschamp, L. ; Requejo-Isidro, J. ; Vandier, C. ; Jaffrès, P-A
European Journal of Medicinal Chemistry, 209, 2021, 112894, DOI: 10.1016/j.ejmech.2020.112894, hal-02997273.



In Vivo Albumin‐Binding of a C‐Functionalized Cyclam Platform for 64Cu‐PET/CT Imaging in Breast Cancer Model
Thomas Le Bihan, Cathryn H. S. Driver, Thomas Ebenhan, Nathalie Le Bris, Jan Rijn Zeevaart and Raphaël Tripier
Chem. Med. Chem., 2020, early., DOI: 10.1002/cmdc.202000800


A Different Approach: Highly Encapsulating Macrocycles Being Used as Organic Tectons in the Building of CPs
Esteban-Muriel, A.; Laglera-Gándara, C. J.; Mato-Iglesias, M.; Tripier, R.; Beyler, M.; de Blas, A. and Rodríguez-Blasa, T.
Cryst. Eng. Comm., 2020, adv., DOI:10.1039/D0CE01499K


Reactivities of Cyclam Derivatives with Metal–Amyloid-β
Gunhee Kim, Evan Lelong, Juhye Kang, Jong-Min Suh, Nathalie Le Bris, Hélène Bernard, Dongwook Kim, Raphaël Tripier and Mi Hee Lim
Inorg. Chem. Front., 2020, adv., DOI: 10.1039/D0QI00791A

  68Ga-Labelled Carbon Nanoparticles for Ventilation PET/CT Imaging: Physical Properties Study and Comparison with Technegas®
Blanc-Béguin, F.; Elies, P.; Robin, P.; Tripier, R.; Kervarec, N.; Lemarié,C. A.; Hennebicq, S.; Tromeur,  C.; Cogulet, V.; Salaün, P.-Y.; Le Roux, P.-Y.
Mol. Imaging Biol, 2020, adv., DOI: 10.1007/s11307-020-01532-6


Enabling Indium Channels for Mass Cytometry by Using Reinforced 2 Cyclam-Based Chelating Polylysine
Grenier, L.; Beyler, M.; Closson, T.; Zabinyakov, N.; Bouzekri, A.; Zhang, Y.; Mayanantham Pichaandi, J.; Winnik, M. A.; Liu, P.; Ornatsky, O.I.; Baranov, V. and Tripier, R,
Bioconj. Chem., 2020, ASAP, DOI: 10.1021/acs.bioconjchem.0c00267


Formation of Heteropolynuclear Lanthanide Complexes Using 2 Macrocyclic Phosphonated Cyclam-Based Ligands
Knighton, R. C.; Soro, L. K.; Troadec, T.; Mazan, V.; Nonat, A. N.; Elhabiri, M.; Saffon-Merceron, N.; Djenad, S.; Tripier, R. and Charbonnière, L. J.
Inorg. Chem., 2020, ASAP article, DOI: 10.1021/acs.inorgchem.a0c01456


Efficient Luminescence Control in a Dithienylethene Functionalized Cyclen Lanthanide Macrocyclic Complexes
Al Sabea, H.; Hamon, N.; GALANGAU, O.; Norel, L.; Maury, O.; Riobé, F.; Tripier, R.  and Rigaut, S.
Inorg. Chem. Front., 2020, adv., DOI: 10.1039/D0QI00354A


M(H2O)(PO3C10H6OH)·(H2O)0.5 (M = Co, Mn, Zn, Cu): a new series of layered metallophosphonate compounds obtained from 6-hydroxy-2-naphthylphosphonic Acid
Beaubras, F.; Rueff, J.M.; Perez, O.; Veillon, F. ; Caignaert, V.; Lohier, J.F.; Cardin, J.; Rogez, G.; Jestin, C.; Couthon, H.; Jaffrès, P.A.
Dalton Trans., 2020, 49, 3877, DOI: 10.1039/c9dt03947c


Pyclen based Ln(III) complexes as highly luminescent bioprobes for in vitro and in vivo one- and two-photon bioimaging applications.
Hamon, N.; Roux, A.; Beyler, M.; Mulatier, J-C; Andraud, C.; Nguyen, C.; Maynadier, M.; Bettache, N.; Duperray, A.; Grichine, A.; Brasselet, S.; Gary-Bobo, M.; Maury, O. and Tripier, R.
J. Am. Chem. Soc., 2020, ASAP, DOI: 10.1021/jacs.0c03496


Unexpected Trends in the Stability and Dissociation Kinetics of Lanthanide(III) Complexes with Cyclen-Based Ligands across the Lanthanide Series
Garda, Z.; Nagy, V.; Rodríguez-Rodríguez, A.; Pujales-Paradela, R.; Patinec, V.; Angelovski, G.; Tóth, É.; Kálmán, F. K.; Esteban-Gómez, D.; Tripier, R.; Platas-Iglesias, C.; Tircsó, G.
Inorg. Chem., 2020, early view, DOI: 10.1021/acs.inorgchem.0c00520


A Squaraine-based Dipicolylamine Derivative Acting as a Turn-on Mercury(II) Fluorescent Probe in Water.
Esteves, C. V.; Costa, J.; Bernard, H.; Tripier , R. and Delgado, R
New J. Chem., 2020, on line, DOI: 10.1039/D0NJ00852D


Cationic Biphotonic Lanthanide Luminescent Bioprobes Based on Functionalized Cross-Bridged Cyclam Macrocycles.
Mendy, J.; Roux, A.; Mulatier, J.-C.; Duperray, A.; Grichine, A.; Guyot, Y.; Brasselet, S.; Riobé, F.; Andraud, C.; Le Guennic, B.; Patinec, V.; Tripier, R.; Beyler, M.; MAURY, O.; Thy Bui, A.; Curton, D.
ChemPhysChem., 2020, on line, DOI: 10.1002/cphc.202000085


Synthesis, Conformational Analysis, and Complexation Study of an Iminosugar-Aza-Crown, a Sweet Chiral Cyclam Analog.
Bordes, A.; Poveda, A.; Troadec, T.; Franconetti, A.; Ardá, A.; Perrin, F.; Ménand, M.; Sollogoub, M. ; Guillard, J.; Désiré, J.; Tripier, R.; Jiménez-Barbero, J. and Blériot, Y.
Org. Lett., 2020, online , DOI: 10.1021/acs.orglett.0c00503


Branched lipid chains to prepare cationic amphiphiles producing hexagonal aggregates: supramolecular behavior and application to gene delivery.
Bouraoui, A.; Rosy Ghanem, R.; Berchel, M.; Deschamps, L.; Vié, V.; Paboeuf, G.; Le Gall, T.;Montier, T.; and Jaffrès, P.A.
Org. Biomol. Chem., 2020,18, 337-345, DOI: 10.1039/C9OB02381J


Picolinate-appended tacn complexes for bimodal imaging: Radiolabeling, relaxivity, photophysical and electrochemical studies
Guillou, A,; Galland, M.; Roux, A.; Varadi, B.; Gogolak, A.; Le Saëc, P.; Faivre-Chauvet, A.; Beyler, M.; Bucher, C.; Tircsó, G.; Patinec, V.; Maury, O.; Tripier, R.
J. Inorg. Biochem., 2019, on line, DOI : 10.1016/j.jinorgbio.2019.110978

Lipidic alkaloids as SK3 channel modulators. Synthesis and biological evaluation of 2-substituted tetrahydropyridine derivatives with potential anti-metastatic activity
Kouba, S.; Braire, J.; Félix, R.; Chantôme, A.; Jaffrès, P.A.; Lebreton, J.; Dubreuil, D.; Pipelier, M.; Zhang, X.; Trebak, M.; Vandier, C.; Mathé-Allainmat, M.; Potier-Cartereau, M.
Eur. J. Med. Chem., 2020, 186, 111854, DOI: 10.1016/j.ejmech.2019.111854



Highly stable and inert complexation of Indium(III) by reinforced cyclam dipicolinate and a bifunctional derivative for bead encoding in mass cytometry
Grenier, L.; Beyler, M.; Platas-Iglesias, C.; Closson, T.; Esteban Gómez, D.; Seferos, D. S.; Liu, P.; Ornatsky, O. I.; Baranov, V. and Tripier, R.
Chemistry A Eur. J. , 2019, ASAP. DOI: 10.1002/chem.201903969
Published online 03 September 2019


Bis‐Thioether‐Containing Lipid Chains in Cationic Amphiphiles: Physicochemical Properties and Applications in Gene Delivery
Bouraoui, A.; Ghanem, R.; Berchel, M.; Vié, V.; Le Guen, Y.; Paboeuf, G.; Deschamps, L.; Le Gall, T.; Montier, T.; Jaffrès, P-A.
ChemPhysChem, 2019, 20, 2187-2194 DOI: 10.1002/cphc.201900626
Published online 08 August 2019


TE1PA as innovating chelator for 64Cu immuno-TEP imaging: a comparative in vivo study with DOTA/NOTA  by conjugation on 9E7.4 mAb in a syngeneic multiple myeloma model
Navarro, A-S.; Le Bihan, T.; Le Saëc, P.; Le Bris, N.; Bailly, C.; Saï-Maurel, C.; Bourgeois, M.; Chérel, M.; Tripier, R. and Faivre-Chauvet, A.
Bioconjugate Chem. , 2019, ASAP, DOI: 10.1021/acs.bioconjchem.9b00510
Published online August 6, 2019


Synthesis of Orthogonal N-Protected C-functional Side-Bridged Cyclams to give access to unsymmetrical constrained BCAs
Le Bihan, T.; Le Bris, N.; Bernard, H.; Platas-Iglesias, C.; Tripier, R.
Eur. J. Org. Chem. , 2019, ASAP, DOI: 10.1002/ejoc.201901013
Published online 01 August 2019


Antibacterial and transfection activities of nebulized formulations incorporating long n-alkyl chain silver N-heterocyclic carbene complexes
Mottais, A.; Berchel, M.; Le Gall, T.; Sibiril, Y.; d’Arbonneau, F.; Laurent, V.; Jaffrès, P.A.; Montier, T.
Inter. J. Pharm., 2019, 567, 118500, DOI: 10.1016/j.ijpharm.2019.118500
Published online 6 July 2019


Designing of a Magnetodielectric System in Hybrid Organic–Inorganic Framework, a Perovskite Layered Phosphonate MnO3PC6H4‐m‐Br⋅H2O
Basu, T.; Bloyet, C.; Beaubras, F.; Caignaert, V.; Perez, O.; Rueff, J.M.; Pautrat, A.; Raveau, B.; Lohier, J.F.; Jaffrès, P.A.; Couthon, H.; Rogez, G.; Taupier, G. and Dorkenoo, H.
Adv. Funct. Mater., 2019, 1901878, DOI: 10.1002/adfm.201901878


Phosphate and polyphosphate anions recognition by a dinuclear copper(II) complex of an unsymmetrical squaramide
Esteves, C. V.; Costa, J.; Esteban, D.; Lamosa, P.; Bernard, H.; Platas-Iglesias, C.; Tripier, R.  and  Delgado, R. 
Dalton Trans. , 2019, ASAP, DOI: 10.1039/C9DT01434A


What is the best radionuclide for immuno-PET of multiple myeloma? A
comparison study between 89Zr- and 64Cu-labeled anti-CD138 in a preclinical
syngeneic model.

Bailly, C.; Gouard, S.; Guérard, F.; Chalopin, B.; Carlier, T.; Faivre-Chauvet, A.; Remaud-Le Saëc, P.; Bourgeois, M.; Chouin, N.; Rbah-Vidal, L.; Tripier, R.; Haddad, F.; Kraeber-Bodéré, F.; Bodet-Milin, C.; Chérel, M.
International Journal of Molecular Sciences, 2019, 20(10), 2564, DOI: 10.3390/ijms20102564


Endo- versus Exocyclic Coordination in Copper Complexes with Methylthiazolylcarboxylate Tacn Derivatives.
GUILLOU, A.; Lima, L.M.P.; Esteban, D.; Delgado, R.; Platas-Iglesias, C.; Patinec, V. and Tripier, R.
Dalton Trans., 2019, 48, 8740-8755, DOI: 10.1039/C9DT01366K


Lipid‐Based Quaternary Ammonium Sophorolipid Amphiphiles with Antimicrobial and Transfection Activities.
Stevens, C. V.; Delbeke, E.; Everaert, J.; Rigole, P.; Coeneye, T.; Roelants, S.; Soetaert, W.; Van Bogaert, I.; Van Geem, K.; Lozach, O.; Berchel, M.; Montier, T.; Jaffres, P.-A.; Brennich, M.; Baccile, N.
ChemSusChem, 2019, 12, (15), 3642-3653, DOI: 10.1002/cssc.201900721


A “Multi-Heavy-Atom” Approach Toward Biphotonic Photosensitizers With Improved Singlet Oxygen Generation Properties
Galland, M.; Le Bahers, T.; Banyasz, A.; Lascoux, N.; Duperray, A.; Grichine, A.; Tripier, R.; Guyot, Y.; Maynadier, M.; Nguyen, C.; Gary-Bobo, M.; Andraud, C.; Monnereau, C.; Maury O.
Chemistry Eur. J. , 2019, ASAP, DOI: 10.1002/chem.201901047


Do transparent exopolymeric particles (TEP) affect the toxicity of nanoplastics on Chaetoceros neogracile?
González-Fernández, C; Toullec, J.; Lambert, C.; Le Goïc, N.; Seoane, M.; Moriceau, B.; Huvet, H.; Berchel, M.; Vincent, D.; Courcot, L.; Soudant; P.; Paul-Pont, I.
Environmental Pollution, Volume 250, 2019, 873-882, DOI: 10.1016/j.envpol.2019.04.093


Aerosol Delivery to the Airways Using Cationic Lipid Nanocomplexes in a Perspective of Cystic Fibrosis Treatment
Berchel, M,; Jaffrès, P-A.; Le Gall, T.; Montier, T.
ACS Symposium Series, 2019, Volume 1309, Chapitre 2, pages 35-58, DOI: 10.1021/bk-2019-1309.ch002

Substitution of unsaturated lipid chains by thioether containing lipid chains in cationic amphiphiles: physico-chemical consequences and application for gene delivery.
Bouraoui, A.; Berchel, M.; Ghanem, R.; Vié, V.; Paboeuf, G.; Deschamps, L.; Lozach, O.; Le Gall, T.; Montier T. and Jaffres P.A.
Org. Biomol. Chem., 2019, 17, 3361-3373, DOI: 10.1039/C9OB00473D


Surface functionalization determines behavior of nanoplastic solutions in model aquatic environments
Tallec, K.; Blard, O.; González-Fernández, C.; Brotons, G.; Berchel, M.; Soudant, P.; Huvet, A.; Paul-Pont, I.
Chemosphere, 2019, 225, 639-646, DOI: 10.1016/j.chemosphere.2019.03.077


Design and Synthesis of Hybrid PEGylated Metal Monopicolinate Cyclam Ligands for Biomedical Applications
Aouidat, F.; Halime, Z.; Moretta, R.; Rea, I.; Filosa, S.; Donato, S.; Tate, R.; De Stefano, L.; Tripier, R.; Spadavecchia, J.
ACS Omega, 2019, 4 (2), pp 2500–2509, DOI: 10.1021/acsomega.8b03266


Methylthiazolyl Tacn Ligands for Copper Complexation and their BCA Derivatives for Bioconjugation and 64Cu Radiolabeling: An Example with Bombesin.
Guillou, A.; Lima, L. M. P.; Esteban-Gómez, D.; Le Poul, N.; Bartholomä, M. D.; Platas-Iglesias, C; Delgado, R.; Patinec, V. and Tripier, R.
Inorg. Chem., 2019, 58, 2669-2685, DOI : 10.1021/acs.inorgchem.8b03280


Organophosphorus Chemistry: From Molecules to Applications (2019)
Recent Developments in Phosphonium Chemistry
Mathieu Berchel, Paul-Alain Jaffrès
Wiley- VCH, 592 pages, Editor: Viktor Iaroshenko, March 2019, ISBN: 978-3-527-33572-5



Dendritic Cell Targeting mRNA Lipopolyplexes combine strong antitumor T‑Cell immunity with improved inflammatory safety.
K. Van der Jeught, S. De Koker, L. Bialkowski, C. Heirman, P. Tjok Joe, F. Perche, S. Maenhout, S. Bevers, K. Broos, K. Deswarte, V. Malard, H. Hammad, P. Baril, T. Benvegnu, P.A. Jaffrès, S. A. A. Kooijmans, R. Schiffelers, S. Lienenklaus, P. Midoux, C. Pichon, K. Breckpot, K. Thielemans
ACS Nano, 2018, 12 (10), pp 9815–9829, DOI:10.1016/j.jconrel.2018.03.035
Published online September 26, 2018

Incipient spin-dipole coupling in a 1D helical-chain metal-organic hybrid
Basu, T.; Bloyet, C.; Rueff, J.M.; Caignaert, V.; Pautrat, A.; Raveau, B.; Rogez, G.; Jaffrès, P.A.
J. Mater. Chem. C, 2018, 6, 10207-10210 , DOI: 10.1039/C8TC04328K
Published online 13 Septembre 2018

One-Dimensional Fluorene-Based Co(II) Phosphonate Co(H2O)2PO3C–C12H9·H2O: Structure and Magnetism
Bloyet, C.; Rueff, J.M.; Perez, O.; Pautrat, A.; Caignaert, V.; Raveau, B.; Rogez, G.; Jaffrès, P.A.
Inorganics 2018, 6(3), 93 , DOI: 10.3390/inorganics6030093
Published online 5 September 2018


Manganese Fluorene Phosphonates: Formation of Isolated Chains
Bloyet, C.; Rueff, J.M.; Caignaert, V.; Raveau, B.; Lohier, J.F.; Roger, M.; Rogez, G.; Jaffrès, P.A.
Inorganics 2018, 6(3), 92 , DOI: 10.3390/inorganics6030092
Published online 5 September 2018


Nanoplastics impaired oyster free living stages, gametes and embryos
Tallec, K.; Huvet, A.; Di Poi, C.; González-Fernández, C.; Lambert, C.; Petton, B.; Le Goïc, N.; Berchel, M.; Soudant, P.; Paul-Pont, I.
Environ. Pollut., 2018, 1226-1235, DOI: 10.1016/j.envpol.2018.08.020
Published online 8 August 2018


Excimer and Red Luminescence Due to Aggregation-Induced
Emission in Naphthalene Based Zinc Phosphonate

Bloyet, C.; Rueff, J.M.; Cardin, J.; Caignaert, V.; Doualan, J.L.; Lohier, J.F.; Jaffrès, P.A.; Raveau B.
Eur. J. Inorg. Chem., 2018, 3095-3103, DOI:
Published online 28 June 2018


Cellular responses of Pacific oyster (Crassostrea gigas) gametes exposed in vitro to
polystyrene nanoparticles

Gonzalez-Fernandeza, C,; Tallec, K.; Le Goica, N.; Lambert, C.; Soudant, P.; Huvet, A.; Suquet, M.; Berchel, M. et Paul-Pont, I.
Chemosphere, 2018, 764-772, DOI: 10.1016/j.chemosphere.2018.06.039
Published online 6 June 2018


Synthesis and biological evaluation of bolaamphiphilic sophorolipids
Delbeke, E.I. P.; Everaert, J.; Lozach, O.; Le Gall, T.; Berchel, M.; Montier, T.; Jaffrès, P.A.; Rigole, P.; Coenye, T.; Brennich, M.; Baccile, N.; Roelants, S.; Soetaert, W.; Van Bogaert, I. N. A.; Marcel Van Geem, K.; and Stevens, C.V.
ACS Sus. Chem. & Engineering, 2018, 8992–9005, DOI: 10.1021/acssuschemeng.8b01354
Published online May,21, 2018


Expanding the Family of Pyclen-Based Ligands Bearing Pendant Picolinate Arms for Lanthanide Complexation.
Le Fur, M.; Molnár, E.; Beyler, M.; Kálmán, F. K.; Fougère, O.; Esteban-Gómez, D.; Rousseaux, O.; Tripier, R.; Tircsó, G. and Platas-Iglesias, C.
Inorg. Chem., 2018, 6932–6945, DOI: 10.1021/acs.inorgchem.8b00598
Published online 30 May 2018


Combining pyclen framework with conjugated antenna for the design of europium and samarium luminescent bioprobes.
Hamon, N., Galland, M.; Le Fur, M.; Roux, A.; Duperray, A.; Grichine, A.; Andraud, C.; Le Guennic, B.; Beyler, M.; Maury, O. and Tripier, R.
Chem. Comm., 2018, 6173-6176, DOI: 10.1039/c8cc02035c
Published online 30 May 2018


Steric Effects on the Binding of Phosphate and Polyphosphate Anions by Zinc(II) and Copper(II) Dinuclear Complexes of m-Xylyl-bis-cyclen.
Esteves, C. V.; Esteban-Gómez, D.; Platas-Iglesias, C.; Tripier, R.; Delgado R.
Inorg. Chem., 2018, 6466–6478, DOI: 10.1021/acs.inorgchem.8b00539.
Published online May 11, 2018


Preclinical evaluation of mRNA trimannosylated lipopolyplexes as therapeutic cancer vaccines targeting dendritic cells.
Le Moignic, A.; Malard, V.; Benvegnu, T.; Lemiègre, L.; Berchel, M.; Jaffrès, P.-A.; Baillou, C.; Delost, M.; Macedo, R.; Rochefort, J.; Lescaille, G.; Pichon, C.; Lemoine, F.M.; Midoux, P. and Mateo, V.
J. Controlled Release, 2018, 100-121, DOI:10.1016/j.jconrel.2018.03.035
Published online 28th May 2018


Synthesis of a C-functionalized TE1PA and comparison with analogues. Example of bioconjugation on 9E7.4 mAb for multiple myeloma 64Cu-PET imaging.
Le Bihan, T.; Navarro, A-S.; Le Bris, N.; Le Saëc, P.; Gouard, S.; Haddad, F.; Gestin, J-F.; Chérel, M.; Faivre-Chauvet, A. and Tripier, R.
Org. Biomol. Chem., 2018, 4261-4271, DOI: 10.1039/C8OB00499D
Publish online 10 April 2018

Kinetics is crucial when targeting copper ions to fight Alzheimer’s disease: an illustration with azamacrocyclic ligands.
Conte-Daban, A,; Beyler, M.; Tripier, R. and Hureau C.
Chem. Eur. J, 2018, 8447-8452, DOI: 10.1002/chem.201801520
Publish online 3 April 2018


Synthesis of Alkyl-Glycerolipids Standards for Gas Chromatography Analysis: Application for Chimera and Shark Liver Oils.
Pinault, M.; Guimaraes, C.; Couthon, C.; Thibonnet, J.; Fontaine, D.; Chantôme, A.; Chevalier, S.; Besson, P.; Jaffrès, P.A. et Vandier, C.
Marine Drugs, 2018, 16, 101, DOI: 10.3390/md16040101

Stable and Inert Yttrium(III) Complexes with Pyclen-Based Ligands Bearing Pendant Picolinate Arms: Toward New Pharmaceuticals for β-Radiotherapy
Le Fur, M.; Beyler, M.;; Molnár, E.; Fougère, O.; Esteban-Gómez, D.; Tircsó, G.; Platas-Iglesias, C.; Lepareur, N.; Rousseaux, O. and Tripier R.
Inorg. Chem., 2018, 57 (4), pp 2051–2063, DOI: 10.1021/acs.inorgchem.7b02953
Published online 5 February 2018


Comparison of Immuno-PET of CD138 and PET imaging with 64CuCl2 and 18F-FDG in a preclinical syngeneic model of multiple myeloma.
Bailly, C.; Gouard, S.; Lacombe, M.; Remaud-Le Saëc, P.; Chalopin, B.; Bourgeois, M.; Chouin, N.; Tripier, R.; Halime, Z.; Haddad, F.; Faivre-Chauvet, A.; Kraeber-Bodéré, F.; Chérel, M.; Bodet-Milin, C.
Oncotarget, 2017, 9:9061-9072, DOI : 10.18632/oncotarget.23886
Published online: January 3rd 2018


A Coordination Chemistry Approach to Fine-Tune the Physicochemical Parameters of Lanthanide Complexes Relevant to Medical Applications.
Le Fur, M.; Molnár, E.; Beyler, M.; Kálmán, F. K..; Fougère, O.; Esteban-Gómez, D.; Rousseaux, O.; Tripier, R.; Tircsó, Gy. and Platas-Iglesias, C.
Chemistry Eur. J., 2018, 24, 13, 3127-3131 , DOI : A0.1002/chem. 201705528


 Antibacterial Effect and DNA Delivery Using a Combination of an Arsonium-​Containing Lipophosphoramide with an N-​Heterocyclic Carbene-​Silver Complex - Potential Benefits for Cystic Fibrosis Lung Gene Therapy.
Mottais, A.; Sibiril, Y.; Laurent, V.; Berchel, M.; Jaffres, P.-A.; Gill, D.; Hyde, S.; Montier, T.; Le Gall, T.
International journal of pharmaceutics, 2017, 29-41, DOI: 10.1016/j.ijpharm.2017.11.022


Phosphonic acid: preparation and applications
Sevrain, C.M.; Berchel, M.; Couthon, H. and Jaffrès, P.A.
Beilstein J. Org. Chem., 2017, 13, 2186-2213 , DOI: 10.3762/bjoc.13.219


 Singular Interaction between an Antimetastatic Agent and the Lipid Bilayer: The Ohmline Case.
Herrera, F.E.; Sevrain, C.M.; Jaffrès, P.A.; Couthon, H.; Grélard, A.; Dufourc, E.J.; Chantôme, A.; Potier-Cartereau, M.; Vandier, C.; Bouchet A. M.
ACS Omega, 2017, 2, 6361-6370, DOI: 10.1021/acsomega.7b00936.


Layered Simple Hydroxides Functionalized by Fluorene-Phosphonic Acids: Synthesis, Interface Theoretical Insights, and Magnetoelectric Effect.
Evrard, Q.; Chaker, Z.; Roger, M.; Sevrain, C.M.; Delahaye, E.; Gallart, M.; Gilliot, P.; Leuvrey, C.; Rueff, J-M.; Rabu, P.; Massobrio, C.; Boero, M.; Pautrat, A.; Jaffrès, P-A.; Ori, G.; Rogez, G.
Advanced Functional Materials, 2017, accepted, DOI: 10.1002/adfm.201703576
First published online 11 September 2017


The role of the capping bond effect on pyclen natY3+/90Y3+ chelates: full control of the regiospecific N-functionalization makes the difference
Le Fur, M.; Beyler, M.; Molnár, E.; Fougère, O.; Esteban-Gómez, D.; Tircsó, G.; Platas-Iglesias, C.; Lepareur, N.; Rousseaux O. and Tripier, R.
Chem. Commun., 2017, 53, 9534-9537, DOI: 10.1039/C7CC05088G.
Published online 3 August 2017


Tuning the copper(II) coordination properties of cyclam by subtle chemical modifications.
Camus, N.; Le Bris, N.; Nuryyeva, S.; Chessé, M.; Esteban-Gómez, D.; Platas-Iglesias, C.; Tripier R. and Elhabiri, M.
Dalton Trans., 2017, 46, 11479-11490 , DOI: 10.1039/C7DT00750G
Published online 27 July 2017


Synthesis of α-amino-lipophosphonates as cationic lipids or co-lipids for DNA transfection in dendritic cells.
Berchel, M.; Akhter, S.; Berthe, W.; Gonçalvez, C.; Dubuisson, M.; Pichon, C.; Jaffres, P-A. and Midoux P.
J. Mater. Chem. B, 2017, 5, 6869, DOI: 10.1039/C7TB01080J.
Published online 15 June 2017


Tacn‑based Bifunctional Picolinate Ligands for an Efficient Copper Complexation.
Guillou, A,; Lima, L. M. P.; Roger, M.; Esteban-Gómez, D.; Delgado, R.; Platas-Iglesias, C.; Patinec, V. and Tripier, R.
Eur. J. Inorg. Chem., 2017, 18, 2435-2443, DOI: 10.1002/ejic.201700176

Near Infrared Two photon Imaging using a Bright Cationic Yb(III) Bioprobe Spontaneously Internalized into Live Cells
Bui, A. T.; Beyler, M.; Grichine, A.; Duperray, A.; Mulatier, J.-C.; Guyot, Y. ; Andraud, C.; Tripier, R.; Brasselet, S.; Maury, O.
Chem Commun., 2017, 53, 6005-6008, DOI: 10.1039/C7CC02835K
Published online 9 May 2017


Investigation of the complexation of natZr(IV) and 89Zr(IV) by hydroxypyridinones for the development of chelators for PET imaging applications.
Guérard, F.; Beyler, M.; Lee, Y-S.; Tripier, R.; Gestin, J-F. and Brechbiel, M. W.
Dalton Transactions, 2017, 46, 4749-4758 , DOI: 10.1039/C6DT04625H
Published online 10 March 2017


Spectroscopic properties of a family of mono- to trinuclear lanthanide complexes.
Sy, M.; Esteban-Gómez, D.; Platas-Iglesias, C.; Rodríguez-Rodríguez, A.; Tripier, R. and Charbonnière, L. J.
Eur. J. Inorg. Chem., 2017, 14, 2122–2129, DOI: 10.1002/ejic.201601516.
Published online: 15 February 2017


Self-assembling complexes between binary mixtures of lipids with different linkers and nucleic acids promote universal mRNA, DNA and siRNA delivery.
Colombani, T.; Peuziat, P.; Dallet, L.; Haudebourg, T.; Mével, M.; Berchel, M.; Lambert, O.; Habrant, D.; Pitard, B.
Journal of Controlled Release, 2017, 249, 131–142, DOI: 10.1016/j.jconrel.2017.01.041.
Published online 1 February 2017


 Cyclam te1pa for 64Cu PET imaging. Bioconjugation to antibody, radiolabeling and preclinical application in xenografted colorectal cancer.
Frindel, M.; Le Saëc, P.; Beyler, M.; Navarro, A.-S.; Saï-Maurel, C.; Alliot, C.; Chérel, M.; Gestin, J.-F.; Faivre-Chauvet, A. and Tripier, R.
RSC Advances, 2017, 7, 9272-9283 DOI: 10.1039/c6ra26003a.
Published online 31 Jan 2017


Fluorenyl Zinc Phosphonate Zn(H2O)PO3–C13H9·H2O: Hybrid Columnar Structure with Strong C–H···π Interactions.
Bloyet, C.; Rueff, J-M.; Caignaert, V.; Lohier, J-F.; Cardin, J.; Jaffres, P-A.; Raveau, B.
ZAAC, 2017, 643, 250–255 , DOI: 10.1002/zaac.201600362
Published online 23 December 2016


Definition of the Labile Capping Bond Effect in Lanthanide Complexes.
Rodríguez-Rodríguez, A.; Regueiro-Figueroa, M.; Esteban-Gómez, D. ; Patinec, V.; Tripier, R.; Tircsó, G.; Carniato, F.; Botta M. and Platas‑Iglesias C.
Chemistry A Eur. Journal, 2016, 23 (15), 1110-1117, DOI: 10.1002/chem.201604390.
Published online November 8th 2016



Macrocyclic ligands with picolinate groups, their complexes like their medical uses.
Le Fur, M.; Tripier, R.; Rousseaux, O.; Beyler, M.
Brevet n° FR 3046172, Application n° FR 2015-63346, dépôt le 24 Décembre 2015
Extension Brevet n° WO 2017109217, Application n° WO 2016-EP82644, dépôt le 23 Décembre 2016


 Nouveaux lipides amphiphiles ramifiés
Jaffrès, P.A.; Couthon-Gourvès, H.; Afonso, D.; Montier, T.; Le Gall, T.
Brevet, Patent n° 3041643 Application n° FR 2015-59066, dépôt le 25 septembre 2015.
Extension Patent n° WO 2017051129, application n° WO 2016-FR52410



Topochemical Route from Supramolecular to Hybrid Materials: Tetraphenylmethane-based Tectons and Lanthanum Phosphonate Derivative.
Pérez, O.; Bloyet, C.; Rueff, J-M.; Barrier, N.; Caignaert, V.; Jaffres, P-A. and Raveau, B.
Cryst. Growth Des., 2016, 16 (12), pp 6781–6789, DOI: 10.1021/acs.cgd.6b00823
Published online October 31, 2016


Synthesis of a trimannosylated-equipped archaeal diether lipid for the development of novel glycoliposomes.
Barbeau, J.; Lemiègrea L.; Quelen, A.; Malard, V.; Gao, H.; Gonçalves, C.; Berchel, M.; Jaffrès, P.A.; Pichon, C.; Midoux, P.; Benvegnua, T.
Carbohydrate Research, 2016, 435, 142–148, DOI: 10.1016/j.carres.2016.10.003.
Published online 11 October 2016


On the relationship between NMR chemical shifts of thermally polarized and hyperpolarized 89Y complexes and their solution structures.
Xing, Y.; Jindal, A. K.; Regueiro-Figueroa, M.; Le Fur, M.; Kervarec, N. Zhao, P.; Kovacs, Z.; Valencia, L.; Pérez-Lourido, P.; Tripier, R.; Esteban-Gómez, D.; Platas-Iglesias C.; and Sherry, A. D.
Chemistry A Eur. Journal, 2016, 22, 16657–16667, DOI: 10.1002/chem.201602901.
Published online 10 october 2016


Intracellular Transport Studies of Picolinate Macrocyclic Copper and Lanthanide Complexes.
Santo Domingo Porqueras, D.; Beyler, M.; Tripier, R.; Salerno, M.
Chemistry Select, 2016, 1, 4423-4429, DOI: 10.1002/slct.201600990.
First Published September 16th 2016


Dimeric pyramidal Cu2O6 (H2O)2 unit – A structural invariant of a homologous series of copper-layered phosphonates.
Bloyet, C.; Roger, M.; Rueff, J.M.; Raveau, B.; Lohier, J.F.; Rogez, G.; Jaffrès, P.A.
Eur. J. Inorg. Chem., 2016, 28, 4643–4648 , DOI: 10.1002/ejic.201600613
Published online August, 30th 2016


Glyco-Phospho-glycero-ether lipid as modulator of SK3 ion channel and SK3-dependent cancer cell migration.
Sevrain, C. M.; Berthe, W.; Couthon-Gourvès, H.; Haelters, J.P.; Bouchet, A. M.; Potier-Cartereau, M.; Vandier, C.; Jaffrès, P.A.
Phosphorus, Sulfur, and Silicon and the Related Elements, 2016, 1623-1624, DOI: 10.1080/10426507.2016.1217221.
Published online, August, 17th, 2016


Dinuclear Spin-Crossover Complexes Based on Tetradentate and Bridging Cyanocarbanion Ligands.
Milin, E.; Belaïd, S.; Patinec, V.; Triki, S.; Chastanet, G. and Marchivie, M.
Inorganic Chemistry, 2016, 55 (17), pp 9038–9046, DOI: 10.1021/acs.inorgchem.6b01542
Published online August, 15th, 2016


Catching anions with coloured assemblies: binding of pH indicators by a giant-size polyammonium macrocycle for anion naked-eye recognition.
Bartoli, F.; Bencini, A.; Conti, L.; Giorgi, C.; Paoli, P.; Rossi, P.; Valtancoli, B.; Le Bris, N.; and Tripier, R.
Org. Biomol. Chem., 2016, 14, 8309-8321, DOI: 10.1039/C6OB01474G.
Published online August, 8th, 2016


Magnetic Bistability in Macrocycle-Based FeII Spin-Crossover Complexes: Counter Ion and Solvent Effects.
Milin, E.; Benaicha, B.; El Hajj, F.; Patinec, V.; Triki, S.; Marchivie, M.; Gómez-García, C. J.; and Pillet, S.
Eur. J. Inorg. Chem., 2016, 34, 5305–5314, DOI: 10.1002/ejic.201600660
Published online August, 6, 2016

Pyclen Tri-n-butylphosphonate Ester as Potential Chelator for Targeted Radiotherapy: From Yttrium(III) Complexation to 90Y Radiolabeling.
Le Fur, M.; Beyler, M.; Lepareur, N.; Fougère, O.; Platas-Iglesias, C.; Rousseaux, O. and Tripier, R.
Inorganic Chemistry, 2016, 55 (16), pp 8003–8012, DOI: 10.1021/acs.inorgchem.6b01135.
Published online August, 3rd 2016

Rigid phosphonic acid for the construction of crystalline organic-inorganic hybrid materials.
Roger, M.; Bloyet, C.; Evrard, Q.; Couthon-Gourvès, H.; Berchel, M.; Rueff, J.-M.; Pérez, O.; Rogez, G.; Jaffrès, P.A.
Phosphorus, Sulfur, and Silicon and the Related Elements, 2016, 191, 1482-1484, DOI: 10.1080/10426507.2016.1212048.
Published online July, 22nd 2016


Synthetic phospholipids and phospho-bola-amphiphiles for nucleic acid delivery.
Berchel, M. ; Lozach, O. ; Berthe, W. ; Hernot, S. ; Couthon-Gourvès, H. ; Mottais, A. ; Le Gall, T. ; Midoux, P. ; Montier, T. ; Jaffrès, P.A.
Phosphorus, Sulfur, and Silicon and the Related Elements, 2016, 1485-1487, DOI:10.1080/10426507.2016.1212049.
Published online July, 22nd, 2016.


Elastic Frustration Triggering Photoinduced Hidden Hysteresis and Multistability in a Two-Dimensional Photoswitchable Hofmann-Like Spin-Crossover Metal–Organic Framework.
Milin, E.; Patinec, V.; Triki, S.; Bendeif, E.-E.; Pillet, S.; Marchivie, M.; Chastanet, G.; and Boukheddaden, K.
Inorganic Chemistry, 2016, 55 (22), pp 11652–11661, DOI: 10.1021/acs.inorgchem.6b01081.
Published online July, 21st 2016

Cationic two-photon lanthanide bioprobes able to accumulate in live cells.
Bui, A.-T.; Beyler, M.; Liao, Y.-Y.; Grichine, A.; Duperray, A.; Mulatier, J.-C.; Le Guennic, B.; Andraud, C.; Maury, O.; Tripier, R.
Inorganic Chemistry, 2016, 55 (14), pp 7020–7025, DOI: 10.1021/acs.inorgchem.6b00891.
Published online July, 1st 2016

New disaccharides-based ether lipids for the inhibition of SK3 ion channel.
Berthe, W.; Sevrain, C.M.; Chantôme, A.; Bouchet, A.M.; Gueguinou, M.; Fourbon, Y.; Potier-Cartereau, M.; Haelters, J.P.; Couthon-Gourvès, H.; Vandier, C.; Jaffrès, P.A.
ChemMedChem, 2016, 11, 14, 1531–1539, DOI: 10.1002/cmdc.201600147.
Published online: 9 June 2016


Alkyl ether lipids and lipid raft reorganization in cancer therapy.
Jaffrès, P.A. ; Gajate, C.; Bouchet, A.M.; Couthon-Gourvès, H.; Chantôme, A.; Potier-Cartereau, M.; Besson, P.; Bougnoux, P.; Mollinedo, F.; Vandier, C.
Pharmacology & Therapeutics, 2016, 165, 114-131, DOI: 10.1016/j.pharmthera.2016.06.003.
Published online 8 June 2016


Development of Non-Viral Gene Delivery Systems with Antibacterial Effects Deliverable via Aerosol for Lungs Gene Therapy
Mottais, A ; Le Gall, T; Berchel, M; Sibiril, Y ; Jaffres, PA; Montier, T
Molecular Therapy 2016, 24, S236, DOI: 10.1016/S1525-0016(16)33405-0
Published May 2016


  Triggering bilayer to inverted-hexagonal nanostructures by thiol-ene click chemistry on cationic lipids: consequences on gene transfection.
Afonso, D.; Le Gall, T.; Couthon-Gourvès, H.; Grélard, A.; Prakash, S.; Berchel, M.; Kervarec,N.; Dufourc,E.J.; Montier, T.; Jaffrès, P.A.
Soft Matter, 2016, 12, 4516-4520, DOI: 10.1039/C6SM00609D.
Published online 25 Apr 2016


SK3/TRPC1/Orai1 complex regulates SOCE-dependent colon cancer cell migration: a novel apportunity to modulate anti-EGFR mAb action by the alkyl-lipid Ohmline.
Guéguinou, M.; Harnois, T.; Crottes, D.; Uguen, A.; Deliot, N.; Gambade, A.; Chantôme, A.; Haelters, J.P.; Jaffrès, P.A.; Jourdan, M.L.; Weber, G.; Soriani, O.; Bougnoux, P.; Mignen, O.; Bourmeyster, N.; Constantin, B.; Lecomte, T.; Vandier, C.; Potier-Cartereau, M.
Oncotarget, 2016, Vol.7, N°. 24, 36168-36184 DOI: 10.18632/oncotarget.8786.
First published online April 18, 2016

Improving the stability and inertness of Cu(II) and Cu(I) complexes with methylthiazolyl ligands by tuning the macrocyclic structure
Le Fur, M.; Beyler, M.; Le Poul, N.; Lima, L.M.P.; Le Mest, Y.; Delgado, R.; Platas Iglesias, C.; Patinec V. and Tripier, R.
Dalton Trans., 2016, 45, 7406-7420DOI: 10.1039/C6DT00385K. 
First published online 15 Mar 2016


Evaluation of the transfection efficacies of quaternary ammonium prepared from sophorolipid.
Delbeke, E. I. P.; Lozach, O.; Le Gall, T.; Berchel, M.; Montier, T.; Jaffrès, P.-A.; Van Geem, K.M. and Stevens, C. V.
Org. Biomol. Chem., 2016, 14, 3744-3751, DOI:10.1039/C6OB00241B.
First published online 14 Mar 2016


Complexation of Ln3+ Ions with Cyclam Dipicolinates: A Small Bridge that Makes Huge Differences in Structure, Equilibrium and Kinetic Properties.
Rodríguez-Rodríguez, A.; Regueiro-Figueroa, M.; Esteban-Gómez, D.; Tripier, R.; Tircso, G.; Kalman, F.; Benyei, A.; Tóth, I.; De Blas, A.; Rodriguez-Blas, T.; Platas-Iglesias, C.
Inorg. Chem., 2016, 55 (5), pp 2227–2239, DOI: 10.1021/acs.inorgchem.5b02627.
Publication Date (Web): February 15, 2016


 Recent developments in phosphonium chemistry.
Berchel, M.; Jaffrès, P.A.
Chapitre de livre dans le livre “Organophosphorus Chemistry. From Molecules to Applications”
Edited by V. Iaroshenko, John Wiley & Sons, Inc. Published, accepté
ISBN: 978-3-527-33572-5

 Lipophosphoramidates-based bipolar amphiphiles: syntheses and transfection properties.
Berchel, M.; Le GAll, T.; Lozach, O.; Haelters, J-P.; Montier, T.; Jaffres P-A.
Org. Biomol. Chem., 2016, 14, 2846-2853, DOI:10.1039/C5OB02512E.
First published online 01 Feb 2016


 Important role of phosphoramido linkage in imidazole-based dioleyl helper lipids for liposome stability and primary cell transfection
Mével, M.; Haudebourg, T.; Peuziat, P.; Dallet, L.; Chatin, B.; Lambert, O.; Berchel, M.; Montier, T.; Jaffrès, P-A.; Lehn, P.; Pitard, B.
The journal of gene medicine, 2016, 18, 3-15, DOI: 10.1002/jgm.2869.

 Cyclams with ambidentate methylthiazolyl pendants for a stable, inert and selective Cu(II)/Cu(I) coordination.
Rodríguez-Rodríguez, A.; Halime, Z.; Lima, L.; Beyler, M.; Deniaud, D.; Le Poul, N.; Delgado, R.; Platas-Iglesias, C.; Patinec, V.; Tripier, R.
Inorg. Chem., 2016, 55 (2), p 619-632, DOI: 10.1021/acs.inorgchem.5b01779
Publication Date (Web): December 23, 2015


 Copper–Fluorenephosphonate Cu­(PO3-C13H9)·H2O: A Layered Antiferromagnetic Hybrid
Hugot, N.; Roger, M.; Rueff, J-M.; Cardin, J.; Perez, O.; Caignaert, V.; Raveau, B.; Rogez, G.; Jaffrès, P-A.
European Journal of Inorganic Chemistry, 2016, 2, 266-271 DOI: 10.1002/ejic.201501041
Article first published online: 2 DEC 2015


 Hydrothermal synthesis for new multifonctional materials: A few examples of phosphates and phosphonate-based hybrid materials
Rueff, J.M. ; Poienar M.; Guesdon A.; Martin C.; Maignan A.; Jaffrès, P.A.
Journal of Solid State Chemistry, 2016, 236, 236-245 DOI: 10.1016/j.jssc.2015.09.018.
Available online 21 September 2015




Bifunctional do2pa derivatives, chelates with metallic cations and use thereof.
Oukhatar, F.; Beyler, M.; Tripier, R.
European Patent 2014, n° EP 14 196 637.4
WO2016087667 (A1) 2016-06-09


Chelates of lead(II) and bismuth(III) based on trans-​di-​n-​picolinate tetraazacycloalkanes
Tripier, R.; Platas Iglesias, C. ; Lima, L.; Beyler, M.
WO2014195416 - 2014-12-11, PCT/EP2014061723 - 2014-06-05
US 20160115187, 2016-04-28



  Targeting amyloid peptide using metal complexes.
Santo Domingo Porqueras, D.; Tripier, R.; Beyler, M.; Salerno, M.
Alzheimer's & Dementia, 2015,11, 7, Supplement, 404, DOI: 10.1016/j.jalz.2015.06.355.

 Biophysical properties of cationic lipophosphoramidates: Vesicles morphology, bilayer hydration and dynamics.
Loizeau D.; Jurkiewicz P.; Aydogan G.; Philimonenko A., Mahfoudhi S.; Hozak P.; Maroto A.; Couthon-Gourvès H.; Jaffrès P.-A.; Deschamps L.; Giamarchi P.; Hof M.
Colloids and Surfaces B: Biointerfaces, 2015, 136 , 192-200. DOI: 10.1016/j.colsurfb.2015.09.012.
Published 1 December 2015


 Evaluation of New Fluorescent Lipophosphoramidates for Gene Transfer and Biodistribution Studies after Systemic Administration
Belmadi, N.; Berchel, M; Denis, C.; Berthe, W.; Sibiril, Y.; Le Gall, T.; Haelters, J-P.; Jaffrès, P-A.; Montier, T.
International Journal of Molecular Sciences, 2015, 16 (11), 26055-26076, DOI:10.3390/ijms161125941 (registering DOI)
Published: 2 November 2015


 Gd3+ based Magnetic Resonance Imaging Contrast Agent Responsive to Zn2+
Regueiro Figueroa, M.; Gündüz, S.; Patinec, V.; Logothetis, N.K.; Esteban-Gómez, D.; Tripier, R.; Angelovski, G.; Platas-Iglesias, C.
Inorg. Chem., 2015, 54 (21), pp 10342–10350, DOI: 10.1021/acs.inorgchem.5b01719
Publication Date (Web): October 15, 2015


 "A [Two-Steps / One Week] Synthesis of C-Functionalized Homocyclens and Cyclams. Application to the Preparation of Conjugable BCAs without Chelating Properties Alteration".
Camus, N.; Halime, Z.; Le Bris, N.; Bernard, H.; Beyler, M.; Platas-Iglesias, C.; Tripier, R.
RSC Advances, 2015, 5, 85898-85910, DOI: 10.1039/C5RA17133D.
First published online 25 Sep 2015


 New synthesis of phenyl-isothiocyanate C-functionalised cyclams. Bioconjugation and 64Cu phenotypic PET imaging studies of multiple myeloma with the te2a derivative.
Halime, Z. ; Frindel, M.; Camus, N.; Orain, P.-Y. ; Lacombe, M.; Chérel, M.; Gestin, J.-F. ; Faivre-Chauvet A.; Tripier, R.
Org. Biomol. Chem., 2015,13, 11302-11314, DOI: 10.1039/C5OB01618E.
First published online 22 Sep 2015


 Chelator free gallium-68 radiolabelling of silica coated iron oxide nanorods via surface interactions.
Burke, B. P.; Baghdadi, N.; Kownacka, A. E.; Nigam, S.; Clemente, G. S.; Al-Yassiry, M. M.; Domarkas, J.; Lorch, M.; Pickles, M.; Gibbs, P.; Tripier, R.; Cawthorne, C.; Archibald, S J.
Nanoscale, 2015, 2015, 7, 14889-14896, DOI: 10.1039/C5NR02753E
First published on the web 13th August 2015


 Efficient in vivo transfection and safety profile of a CpG-free and codon optimized luciferase plasmid using a cationic lipophosphoramidate in a multiple intravenous administration procedure
Lindberg, M.F. ; Le Gall, T. ; Carmoy, N. ; Berchel, M. ; Hyde, S.C. ; Gill, D.R. ; Jaffrès, P.A. ; Lehn, P. ; Montier, T.
Biomaterials, 2015, 59, 1-11, DOI: 10.1016/j.biomaterials.2015.04.024.
Published August 2015


Investigating the complexation of the Pb2+/Bi3+ pair with dipicolinate cyclen ligands.
Lima, L. M. P.; Beyler, M.; Delgado, R.; Platas-Iglesias, C.; Tripier, R.
Inorg. Chem., 2015, 54 (14), 7045–7057, DOI: 10.1021/acs.inorgchem.5b01079
Publication Date (Web): July 6, 2015


 Liposome-based Formulation for Intracellular Delivery of Functional Proteins
Chatin B., Mével M.; Devallière J.; Dallet L.; Haudebourg T.; Peuziat P.; Colombani T.; Berchel M.; Lambert O.; Edelman A.; Pitard B.
Molecular Therapy Nucleic Acids, 2015, 4, e244,  DOI:10.1038/mtna.2015.17.
Published online 23 June 2015


 Straightforward and mild deprotection methods of N-mono- and N1,N7-functionalised bisaminal cyclens.
Oukhatar, F.; Beyler, M.; Tripier, R.
Tetrahedron, 2015, 71 (23), 3857-3862. Cover, DOI:10.1016/j.tet.2015.04.021
Published 10 juin 2015


 Rigid phosphonic acids as building blocks for crystalline hybrid materials.
Rueff, J.M. ; Hix, G.B. ; Jaffrès, P.A.,
Book chapter in “Tailored Organic–Inorganic Materials”, First Edition, chapter 9, p341-393.
Edited by Ernesto Brunet, Jorge L. Colón, A. Clearfield, 2015 John Wiley & Sons, Inc. Published 2015 by John Wiley & Sons, Inc. (ISBN: 978-1-118-77346-8). DOI: 10.1002/9781118792223.ch9
Published: June 2015


 Synthetic vectors for gene delivery: An overview of their evolution depending on routes of administration.
By Belmadi N.; Le Gall.; Lehn P.; Midoux P.; Pichon C.; Loyer P.; Le Gall T.; Jaffres P.-A.; Montier T.
Biotechnology journal, 2015, 10 (9), 1370-1389. DOI: 10.1002/biot.201400841.
Article first published online: 3 JUN 2015

 Enhanced achilles tendon healing by fibromodulin gene transfer.
Delalande, A.; Gosselin, M.P.; Suwalski, A.; Guilmain, W.; Leduc, C.; Berchel, M.; Jaffrès, P.A.; Baril, P.; Midoux, P.; Pichon, C.
Nanomedicine : NBM, 2015, 11 (6), 1735-1744. DOI: 10.1016/j.nano.2015.05.004.
Published Online: June 03, 2015


Ultrasound-targeted delivery of chemotherapeutic drug and nucleic acids by gas-filled cationic liposomes.
Delalande, A; Manta, S; Peyret, A; Horvat, L; Ezzine, S; Bessodes, M; Midoux, P; Jaffres, PA; Mignet, N; Pichon, C
Human Gene Therapy, 2015, 26, A19, DOI: 10.1016/S1525-0016(16)33878-3
Published May 2015

 Cationic lipophosphoramidates containing a hydroxylated polar headgroup for improving gene delivery.
Berchel, M.; Le Gall, T.; Haelters J.P.; Montier, T.; Jaffrès, P.A.
Mol. Pharmaceutics, 2015, 12 (6), 1902-1910, DOI: 10.1021/mp500807k.
Publication Date (Web): May 5, 2015


 Synthesis of lipid-based unsymmetrical O,O-dialkylphosphites.
Berchel, M. ; Haddad, J. ; Le Corre, S. ; Haelters, J.P. ; Jaffrès, P.A.
Tetrahedron Letters, 2015, 56, 2345-2348, DOI: 10.1016/j.tetlet.2015.03.093.
Published 29 April 2015


 Metal ions in medical imaging: optical, radiopharmaceutical and MRI contrast.
Archibald, S. J.; Tripier, R.
Dalton Transactions, 2015,44, 4789-4790, DOI: 10.1039/C5DT90036K
First published online 24 Feb 2015

 Silver-based hybrid materials from meta or para phosphonobenzoic acid: Influence of the topology on silver release in water.
Rueff, J.M. ; Perez, O. ; Caignaert, V. ; Hix, G. ; Berchel, M. ; Quentel, F. ; Jaffrès, P.A.
Inorg. Chem., 2015, 54, 2152-2159, DOI: 10.1021/ic502395s
Publication Date (Web): February 13, 2015


 Stable Mn2+, Cu2+ and Ln3+ complexes with cyclen-based ligands functionalized with picolinate pendant arms. Unexpected self-aggregation of the La3+ complex in solution.
Rodríguez-Rodríguez, A.; Garda, Z.; Ruscsák, E.; Esteban-Gómez, D.; De Blas, A.; Rodríguez-Blas, T.; Lima, L. M. P.; Beyler, M.; Tripier, R.; Tircsó, G.; Platas-Iglesias, C.
Dalton Transactions, 2015, 44, 5017-5031: Special issue for the Dalton Discussion 15, DOI: 10.1039/C4DT02985B
First published online 20 Jan 2015


 Cationic dialkylarylphosphates: new family of bio-inspired cationic lipids for gene delivery.
Le Corre, S. S.; Belmadi, N.; Berchel, M.; Le Gall, T.; Haelters, J.P.; Lehn, P.; Montier, T.; Jaffrès, P.A.
Org. Biomol. Chem., 2015, 13, 1122-1132, DOI: 10.1039/c4ob01770f.
First published online 11 Nov 2014

 La1-xLnxH(O3PCH3)2 (Ln=Tb, Eu ; 0<x≤1) : An Organic-Inorganic Hybrid with Lanthanide Chains and Tunable Luminescent Properties.
Muteleta, B. ; Boudin, S. ; Perez, O. ; Rueff, J.M. ; Labbé, C. ; Jaffrès, P.A.
Dalton Trans., 2015, 44, 1186-1192, DOI: 10.1039/c4dt02643h.
First published online 05 Nov 2014



  Synthèse et étude de nouveaux amphiphiles pour la délivrance d'acides nucléiques, Afonso Damien



  Nouveaux lipides amphiphiles ramifiés
Jaffrès, P.A.; Couthon-Gourvès, H.; Afonso, D.; Montier, T.; Le Gall, T.
Brevet, FR 1559066, dépôt le 25 septembre 2015. PCT/FR2016/052410


Macrocyclic ligands with picolinate groups, their complexes like their medical uses.
Le Fur, M.; Tripier, R.; Rousseaux, O.; Beyler, M.
Brevet n° FR 3046172, Application n° FR 2015-63346, dépôt le 24 Décembre 2015



 Lanthanide(III) Complexes with a Reinforced Cyclam Ligand Show Unprecedented Kinetic Inertness.
Rodríguez-Rodríguez, A.; Esteban-Gómez, D.; Tripier, R.; Tircso, G.; Gyula; Garda, Z.; Toth, I.; De Blas, A.; Rodriguez-Blas, T.; Platas-Iglesias, C.
J. Am. Chem. Soc., 2014, 136 (52), 17954-17957, DOI: 10.1021/ja511331n
Publication Date (Web): December 12, 2014


 Cationic trialkylphosphates: synthesis and transfection efficacies compared to phosphoramidate analogues
S. Le Corre, M. Berchel, T. Le Gall, J.P. Haelters, P. Lehn, T. Montier, P.A. Jaffrès
Eur. J. Org. Chem., 2014, 2014 (36), 8041-8048, DOI: 10.1002/ejoc.201403103.
Article first published online: 31 OCT 2014


 H2Me-do2pa: An attractive chelator with fast, stable and inert natBi3+ and 213Bi3+ complexation for potential α radioimmunotherapy applications.
Lima, L. M. P.; Beyler, M.; Oukhatar, F.; Le Saec, P.; Faivre-Chauvet, A.; Platas-Iglesias, C.; Delgado, R.; Tripier, R.
Chem Commun., 2014, 50, 12371-12374, DOI: 10.1039/C4CC05529B
First published online 25 Aug 2014


 Final step gallium-68 radiolabelling of silica coated iron oxide nanorods as potential PET/MR multimodal imaging agents.
Burke, B.; Baghdadi, N.; Clemente, G.; Camus, N.; Guillou, A.; Kownacka, A.; Domarkas, J.; Halime, Z.; Tripier, R.; Archibald, S.J.
Faraday Discuss., 2014, 175, 59-71, DOI: 10.1039/C4FD00137K
First published online 24 Jul 2014

 Effects of a Novel Archaeal Tetraether-based Colipid on the In Vivo Gene Transfer Activity of Two Cationic Amphiphiles
Le Gall, T.; Barbeau, J.; Barrier, S.; Berchel, M.; Lemiègre, L.; Jeftic, J.; Meriadec, C.; Artzner, F.; Gill, D.; Hyde, S.; Férec, C.; Lehn, P.; Jaffrès, P.A.; Benvegnu, T.; Montier, T.
Mol. Pharm., 2014, 11, 2973-2988, DOI: 10.1021/mp4006276.
Publication Date (Web): July 16, 2014


Supramolecular Luminescent Lanthanide Capsules for Fluoride Sequestering and Sensing,
Liu, T.; Nonat, A.; Beyler, M.; Regueiro-Figueroa, M.; Nchimi Nono, K.; Jeannin, O.; Camerel, F.; Debaene, F.; Cianférani-Sanglier, S.; Tripier, R.; Platas-Iglesias, C.; Charbonnière, L. J.
Angew. Chem. Int. Ed, 2014, 53, 29, 7259-7263, DOI: 10.1002/anie.201404847
First published: 6 June 2014


 Synthesis of an unsymmetrical N-functionalized triazacyclononane ligand and its Cu(II) complex.
Roger, M.; Patinec, V.; Tripier, R.; Triki, S.; Le Poul, N.; Le Mest, Y.
Inorganica Chimica Acta, 2014, Invitation Manuscript, 417, 201-207, doi:10.1016/j.ica.2013.12.036
Published 1 June 2014

 Atherton-Todd Reaction: Mechanism, Scope, and Applications.
Le Corre, S.S. ; Berchel, M. ; Couthon-Gourvès, H. ; Haelters, J.P. ; Jaffrès, P.A.
Beilstein J. Org. Chem. (article on invitation), 2014, 10, 1166-1196, DOI: 10.3762/bjoc.10.117.
Published 21 May 2014


 Radiolabelling of HTE1PA: a new monopicolinate cyclam derivative for Cu-64 phenotypic imaging. In vitro and in vivo stability studies in mice.
Frindel, M.; Camus, N.; Rauscher, A.; Bourgeois, M.; Alliot, C.; Barré, L.; Gestin, J.-F.; Tripier, R.; Faivre-Chauvet, A.
Nucl. Med. Biol, 2014, 41, 49-57, DOI:10.1016/j.nucmedbio.2013.12.009
Published May 2014


 Picolinate-Containing Macrocyclic Mn2+ Complexes as Potential MRI Contrast Agents.
Molnár, E.; Camus, N.; Patinec, V.; Rolla, G. A.; Botta, M.; Tircsó, G.; Kálmán, F. K.; Fodor, T.; Tripier, R.; Platas-Iglesia, C.
Inorg. Chem. 2014, 53(10), 5136-5149, DOI: 10.1021/ic500231z
Publication Date (Web): April 28, 2014


 Monopicolinate Cross-bridged Cyclam Combining Very Fast Complexation with Very High Stability and Inertness of its Copper(II) Complex.
Lima, L.; Halime, Z.; Marion, R.; Camus, N.; Delgado, R.; Platas-Iglesias, C.; Tripier, R.
Inorg. Chem. 2014, 53(10), 5269-5279, DOI: 10.1021/ic500491c
Publication Date (Web): April 23, 2014


 Full control of the regiospecific N-functionalization of new C functionalized cyclam bisaminal derivatives and application to the synthesis of their TETA, TE2A and CB-TE2A analogues
Camus, N.; Halime, Z.; Le Bris, N.; Bernard, H.; Platas-Iglesias, C.; Tripier, R.
Journal of Organic Chemistry, 2014, 1885-1899, Featured Article, DOI: 10.1021/jo4028566
Publication Date (Web): February 19, 2014


 Lanthanide complexes with Heteroditopic Ligands as Fluorescent Zinc Sensors.
Roger, M.; Regueiro-Figueroa, M.; Ben Azzeddine, C.; Patinec, V.; Bonnet, C. S. ; Platas-Iglesias, C.; Tripier, R.
Eur. J. Inorg. Chem., 2014, 1072-1081, DOI: 10.1002/ejic.201301426
Article first published online: 17 JAN 2014

 Lipopolyplexes comprising imidazole/imidazolium lipophosphoramidate, histidinylated polyethyleneimine and siRNA as efficient formulation for siRNA transfection. Goncalves, C. ; Berchel, M. ; Gosselin, M.P. ; Malard, V. ; Cheradame, H. ; Jaffrès, P.A. ; Guégan, P. ; Pichon, C. ; Midoux, P.
Int. J. Pharm., 2014, 460, 1-2, 264-272, DOI: 10.1016/j.ijpharm.2013.11.005.
Published 2 January 2014


 Cationic lipophosphoramidates with two different lipid chains: synthesis and evaluation as gene carriers.
Le Corre, S.S. ; Berchel, M. ; Belmadi, N. ; Denis, C. ; Haelters, J.P. ; Le Gall, T. ; Lehn, P. ; Montier, T. ; Jaffrès, P.A.
Org. Biomol. Chem., 2014, 12, 1463-1474, DOI: 10.1039/c3ob42270d.
First published online 20 Dec 2013

 Functionalized Phospholipid Molecular Platform: Use for Production of Cationic Fluorescent Lipids.
Berchel, M.; Haelters, J.P.; Afonso, D.; Maroto, A.; Deschamps, L.; Giamarchi P.A. Jaffrès, P.A.
Eur. J. Org. Chem., 2014, 1076-1083, DOI: 10.1002/ejoc.201301416.
Article first published online: 5 DEC 2013



  Nouveaux lipides cationiques phosphorés pour la délivrance d'acides nucléiques, Le Corre Stéphanie


 Nouvelles stratégies de synthèses de cyclams C- et N-fonctionnalisés : vers des applications en médecine nucléaire, Camus Nathalie.



 Bifunctional do2pa derivatives, chelates with metallic cations and use thereof.
Oukhatar, F.; Beyler, M.; Tripier, R.
European Patent 2014, n° EP 14 196 637.4.


Picolinate cross-bridged cyclams, chelates with metallic cations and use thereof.
Tripier, R.; Halime, Z.
PCT/EP2014074415 - 2014-11-12, WO2015071334 - 2015-05-21


Chelates of lead(II) and bismuth(III) based on trans-​di-​n-​picolinate tetraazacycloalkanes
Tripier, R.; Platas Iglesias, C. ; Lima, L.; Beyler, M.
WO2014195416 - 2014-12-11, PCT/EP2014061723 - 2014-06-05



 Hyperfine Coupling Constants on Inner-Sphere Water Molecules of a TACN-based Mn(II) Complex and Related Systems Relevant as MRI Contrast Agents.
Patinec, V.; Rolla, G.; Botta, M.; Tripier, R.; Esteban-Gómez, D.; Platas-Iglesias, C.
Inorg. Chem. 2013, 52, 19, 11173-11184, DOI: 10.1021/ic4014366
Publication Date (Web): September 26, 2013

Pivotal role of the lipid raft SK3-Orai1 complex in human cancer cell migration and bone metastases
Chantôme, A.; Potier-Cartereau, M.; Clarysse, L.; Fromont, G.; Marionneau-Lambot, S.; Guéguinou, M.; Pagès, J.C.; Collin, C.; Oullier, T.; Girault, A.; Arbion, F.; Haelters, J.P.; Jaffrès, P.A.; Pinault, M.; Besson, P.; Joulin, V.; Bougnoux, P.; Vandier, C.
Cancer Research, 2013, 73, 4852-61, DOI: 10.1158/0008-5472.CAN-12-4572
Published Online First June 17, 2013

DiGalactosyl-Glycero-Ether Lipid: synthetic approaches and evaluation as SK3 channel inhibitor
Sevrain, C.M., Haelters, J.P.; Chantôme, A.; Couthon-Gourvès, H.; Gueguinou, M.; Potier-Cartereau, M.; Vandier, C.; Jaffrès, P.A.
Org. Biomol. Chem., 2013, 11, 4479-4487, DOI 10.1039/c3ob40634b.
First published online 10 May 2013

Arsonium-containing Lipophosphoramides, Poly-functional Nano-carriers for Simultaneous Antibacterial Action and Eukaryotic Cell Transfection
Le Gall, T.; Berchel, M.; Le Hir, S.; Fraix, A.; Salaün, J.Y.; Férec, C.; Lehn, P.; Jaffrès, P.A.; Montier, T.
Adv. Healthcare Mater, 2013, 2, 1513-1524, DOI: 10.1002/adhm.201200478.
Article first published online: 26 APR 2013


 Monopicolinate-dipicolyl derivative of Triazacyclononane for stable complexation of Cu2+ and 64Cu2+.
Roger, M.; Lima, L.; Frindel, M.; Platas-Iglesias, C.; Gestin, J.-F.; Delgado, R.; Patinec, V.; Tripier, R. Inorg. Chem., 2013, 52, 5246-5259, DOI: 10.1021/ic400174r
Publication Date (Web): April 12, 2013

  Physicochemical properties of cationic lipophosphoramidates with an arsonium head group and various lipid chains: A structure-activity approach.
Loizeau, D.; Le Gall, T.; Mahfoudhi, S.; Berchel, M.; Maroto, A.; Yaouanc, J.J. ; Jaffrès, P.A.; Lehn, P.;Deschamps, L.; Montier, T.; Giamarchi, P.
Biophys. Chem., 2013, 171, 46-53, DOI: 10.1016/j.bpc.2012.10.003
Published January 2013


 New bis-tetraamine ligand with a chromophoric 4-(9-anthracenyl)-2,6-dimethylpyridinyl linker for glyphosate and ATP sensing.
Pouessel, J.; Abada, S.; Le Bris, N.; Elhabiri, M.; Charbonnière, L. J. ; Tripier, R.
Dalton Trans., 2013, 42, 4859-4872, DOI: 10.1039/C3DT32325K
First published online 10 Jan 2013


Cationic lipophosphoramidates with two disulfide motifs: synthesis, behaviour in reductive media and gene transfection activity
Fraix, A.; Le Gall, T.; Berchel, M.; Denis, C.; Lehn, P. ; Montier, T. ; Jaffrès, P.A.
Org. Biomol. Chem., 2013, 11, 1650-1658, DOI: 10.1039/c3ob27261c.
First published online 08 Jan 2013



Synthesis of inhibitors of the SK3 channel - potential anti-metastatic compounds - and transfection of RNAi, Sevrain Charlotte


 Nouveaux chélates [triazacyclononane-métaux de transition] : synthèse, complexation et premières applications, Roger Mélissa



Picolinate cross-bridged cyclam, chelate with metallic cations and use thereof.
Tripier, R.; Halime, Z.
European Patent 2013, n° EP 13 192 597.6. WO2015071334 A1


 Investigation of Zr(IV) and 89Zr(IV) complexation with hydroxamates: Progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging.
Guérard, F.; Lee, Y. S.; Tripier, R.; Deschamps, J. R.; Brechbiel, M.W.
Chem. Commun., 2013, 1002-1004, DOI: 10.1039/C2CC37549D
First published online 12 Dec 2012


 Solution Structure of Ln(III) Complexes with Macrocyclic Ligands Through Theoretical Evaluation of 1H NMR Contact Shifts.
Rodríguez-Rodríguez, A.; Esteban-Gómez, D.; De Blas, A.; Rodriguez-Blas, T.; Botta, M.; Tripier, R.; Platas-Iglesias, C.
Inorg. Chem., 2012, 13419-13429, DOI: 10.1021/ic302322r
Publication Date (Web): December 6, 2012

 Structural study of hydrated/dehydrated Manganese Thiophene-2,5-diphosphonate Metal Organic Frameworks, Mn2(O3P-C4H2S-PO3).nH2O.
Rueff, J.M.; Perez, O.; Pautrat, A.; Barrier, N.; Hix, G.; Hernot, S.; Couthon-Gourvès, H.; Jaffrès, P.A
Inorg. Chem., 2012, 51, 10251-10261, DOI: 10.1021/ic301187y.
Publication Date (Web): September 20, 2012


Glyco-Phospho-Glycero Ether Lipid (GPGEL): synthesis and evaluation as Small Conductance Ca2+-Activated K+ Channels (SK3) inhibitor.
Sevrain, C.M. ; Haelters, J.P. ; Chantôme, A.; Couthon-Gourvès, H.; Girault, A.; Vandier, C.; Jaffrès, P.A.
MedChemComm., 2012, 3, 1471-1478, DOI: 10.1039/C2MD20207G.
First published online 14 Sep 2012

The gene transfection properties of a lipophosphoramidate derivative with two phytanyl chains
Lindberg, M.; Carmoy, N. ; Le Gall, T.; Fraix, A.; Berchel, M. ; Lorilleux, C.; Couthon-Gourvès, H. ; Bellaud, P. ; Fautrel, A. ; Jaffrès, P.A.; Lehn, P.; Montier, T.
Biomaterials, 2012, 33, 6240-6253, DOI: 10.1016/j.biomaterials.2012.05.014.
Published: September 2012


 Polyaminoquinoline Iron Chelators for Vectorization of Antiproliferative Agents: Design, Synthesis and Validation.
Deniaud, D.; Corcé, V.; Morin, E.; Guihéneuf, S.; Renault, E.; Renaud, S.; Cannie, I.; Tripier, R.; Lima, L.; Julienne, K.; Gouin, S.; Loreal, O.; Gaboriau, F.
Bioconj. Chem., 2012, 23, 1952-1968, DOI: 10.1021/bc300324c
Publication Date (Web): August 8, 2012


 Exo diastereoisomer of 10-aryl-1,4,7-triazabicyclo[5.2.1]decane as intermediary in specific derivatisation of triazacyclononane
Roger, M.; Patinec, V.; Bourgeois, M.; Tripier, R.; Triki, S.; Handel, H.
Tetrahedron, 2012, 68, 5637-43, DOI:10.1016/j.tet.2012.04.057
Published 8 July 2012


 Glyphosate and ATP binding by mononuclear Zn(II) complexes with non symetric ditopic polyamine ligands.
Pouessel, J.; Le Bris, N.; Bencini, A.; Giorgi, C.; Valtancoli, B.; Tripier, R.
Dalton Trans., 2012, 41, 10521-10532 (+ inside cover), DOI: 10.1039/C2DT31110K
First published online 28 Jun 2012


 "Polyamine Drug Discovery"
Raphael Tripier.
ChemMedChem, 2012, 7, 10, 1859-1860, Book review, DOI: 10.1002/cmdc.201200294
Article first published online: 19 JUN 2012


Monopicolinate cyclen and cyclam derivatives for stable copper(II) complexation.
Lima, L.; Esteban-Gómez, D.; Delgado, R.; Platas-Iglesias, C.; Tripier, R.
Inorg. Chem., 2012, 51 (12), pp 6916–6927, DOI: 10.1021/ic300784v
Published May 31, 2012

 Gene transfer by chemical vectors: Comparative study of the endocytosis routes of polyplexes, lipoplexes and lipopolyplexes in a myoblast cell line.
Billiet, L.; Gonçalves, C.; Gomez, J.P.; Lodewick, J.; Berchel, M.; Jaffrès, PA.; Montier, T.; Lehn, P.; Bertrand, E.; El-Ghoul, Y.; Cheradame, H.; Guégan, P.; Mével, M.; Pitard, B.; Benvegnu, T.; Pichon, C.; Midoux P.
Biomaterials, 2012, 33, 2980-2990, DOI: 10.1016/j.biomaterials.2011.12.027.
Published April 2012

 Copper(II) n-alkylphosphonates used as nanofiller: single crystal, powder structure studies and influence of the alkyl chain length on the magnetic properties.
Chausson, S. ; Rueff, J.M.; Lepetit, M.B.; Perez, O.; Retoux, R.; Simon, Le Pluart, L.; Jaffrès, P.A.
Eur. J. Inorg. Chem., 2012, 2193-2202, DOI : 10.1002/ejic.201101218.
Article first published online: 15 March 2012

 Targeting SKCa Channels in Cancer: Potential New Therapeutic Approaches.
Girault, A. ; Haelters, J.P. ; Potier-Cartereau, M. ; Chantome, A. ; Jaffrès, P.A ; Bougnoux, P. ; Joulin, V. ; Vandier, C.
Curr. Med. Chem., 2012, 19, 697-713 (Review), DOI: 10.2174/092986712798992039.

 Gene transfer by histidylated lipopolyplexes: A dehydration method allowing preservation of their physicochemical parameters and transfection efficiency
Perche, F.; Lambert, O.; Berchel, M.; Jaffrès, P.A.; Pichon, C.; Midoux, P.
Int. J. Pharm., 2012, 423, 144-150, DOI: 10.1016/j.ijpharm.2011.04.009.
Published: 14 February 2012

 Synthesis of lipophosphoramidyl-cyclodextrins and their supramolecular properties.
Gervaise, C. ; Bonnet, V. ; Wattraint, O. ; Aubry, F. ; Sarazin, C. ; Jaffrès, P.A. ; Djedaïni-Pilard, F.
Biochimie, 2012, 94, 66-74, DOI: 10.1016/j.biochi.2011.09.005.
Published January 2012


 Lanthanide(III) complexes with ligands derived from a Cyclen framework containing pyridinecarboxylate pendants. The Effect of Steric Hindrance on the Hydration Number.
Rodríguez-Rodríguez, A.; Esteban-Gómez, D.; De Blas, A.; Rodríguez-Blas, T.; Botta, M.; Tripier, R.; Platas-Iglesias, C.
Inorg. Chem. 2012, 51, 2509-2521, DOI: 10.1021/ic202436j
Publication Date (Web): January 13, 2012

 Lipophosphonate/lipophosphoramidates: a family of synthetic vectors efficient for gene delivery.
Berchel,M.; Le Gall,T.; Couthon-Gourvès,H. ; Haelters, J.P. ; Montier, T. ; Midoux, P. ; Lehn, P. ; Jaffrès, P.A.
Biochimie, 2012, 94, 33-41 (Review), DOI: 10.1016/j.biochi.2011.07.026.
Published January 2012


 Lipothiophosphoramidates for gene delivery: critical role of the cationic polar headgroup.
Fraix, A.; Montier, T.; Le Gall, T.; Sevrain, C.; Carmoy, N.; Lindberg, M.; Lehn, P.; Jaffrès, P.A.
Org. Biomol. Chem., 2012, 10, 2051-2058, DOI: 10.1039/c2ob06812e.
First published online 21 Dec 2011



 Preparation process of functionnalized tetraazacycloalkanes via a particular cyclic bisaminal compound.
Tripier, R.; Camus, N.
WO2013072491 - 2013-05-23, PCT/EP2012072898 - 2012-11-16



 New Alkyl-Lipid Blockers of SK3 Channels Reduce Cancer Cell Migration and Occurence of Metastasis.
Girault, A. ; Haelters, J.P. ; Potier, M. ; Chantôme, A. ; Pineau, M. ; Marionneau-Lambot, S. ; Oullier, T. ; Simon, G. ; Couthon-Gourvès, H. ; Jaffrès, P.A. ; Joulin, V. ; Corbel, B. ; Bougnoux, P. ; C. Vandier, C.
Current Cancer Drug Target, 2011, 11, 1111-1125, DOI: 10.2174/156800911798073069.


Cyclen-Based Lanthanide Complexes as Luminescent Anion Receptors.
Lima, L. M. P.; Tripier, R.
Current Inorganic Chemistry, 2011, issue 1, 36-60, DOI: 10.2174/1877944111101010036


Positively Charged Lanthanide Complexes with Cyclen-Based Ligands: Synthesis, Solid State and Solution Structure, and Fluoride Interaction.
Lima, L.; Lecointre, A. ; Morfin, J.-F.; De Blas, A.; Visvikis, D.; Charbonnière, L. J. ; Platas-Iglesias, C.; Tripier, R.
Inorg. Chem. 2011, 50, 12508, 12516, DOI: 10.1021/ic201447c
Publication Date (Web): November 9, 2011


 Selective binding of glyphosate by a ditopic cyclic-open-chain polyazaligand in aqueous solution.
Pouessel, J.; Le Bris, N.; Bencini, A.; Giorgi, C.; Handel, H.; Tripier, R.
Eur. J. Org. Chem., 2011, 35, 6965-6973, DOI: 10.1002/ejoc.201100972
Article first published online: 10 OCT 2011

 Modular construction of fluorescent lipophosphoramidates by click chemistry.
Berchel, M. ; Haelters, J.P. ; Couthon-Gourvès, H. ; Deschamps, L. ; Midoux, P. ; Lehn, P. ; Jaffrès, P.A.
Eur. J. Org. Chem., 2011, 6294-6303, DOI: 10.1002/ejoc.201100900.
Article first published online: 13 SEP 2011

 Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA.
Perche, F. ; Benvegnu, T.; Berchel, M. ; Lebegue, L. ; Pichon, C. ; Jaffrès, P.A. ; Midoux P.
Nanomedicine: NBM 2011, 7, 445-453, DOI: 10.1016/j.nano.2010.12.010.
Published August 2011


 Exploring new molecular architectures for anion recognition: synthesis and ATP binding properties of new cyclam-based ditopic polyammonium receptors.
Pouessel, J.; Bazzicalupi, C.; Bencini, A.; Bernard, H.; Giorgi, C.; Handel, H.; Matera, I.; Le Bris, N.; Tripier, R.; Valtancoli, B.
Chemisty an Asian Journal, 2011, 6 (6), 1582-1594, DOI: 10.1002/asia.201100046
First published: 9 May 2011

 A silver-based Metal Organic Framework material as a ‘reservoir’ of bactericidal metal ions.
Berchel, M. ; Le Gall, T. ; Denis, C. ; Le Hir, S. ; Quentel, F. ; Elléouet, C. ; Montier, T. ; Rueff, J.M. ; Salaün, J.Y. ; Haelters, J.P. ; Lehn, P. ; Hix, G.B. ; Jaffrès, P.A.
New J. Chem., 2011, 35, 1000-1003, DOI: 10.1039/C1NJ20202B.
First published online 07 Apr 2011


 Synthesis, complexation and NMR relaxation properties of the conformation-switching Gd3+ complexes of Mes(DO3A)3.
Miéville, P.; Jaccard, H.; Reviriego, F.; Tripier, R.; Helm, L.
Dalton Transactions, 2011, 40 (16), 4260 – 4267, DOI: 10.1039/C0DT01597K
First published online 31 Mar 2011


 Trans-methylpyridine cyclen versus cross-bridged trans-methylpyridine cyclen. Synthesis, acid-base and metal complexation studies (metal = Co2+, Cu2+, and Zn2+).
Bernier, N.; Costa, J.; Delgado, R.; Felix, V.; Royal, G.; Tripier, R.
Dalton Transactions, 2011, 40 (17), 4514 – 4526, DOI: 10.1039/C0DT01191F
First published online 16 Mar 2011

1,2,4-Triazine method of bipyridine ligand synthesis for new luminescent Eu(III) complexes preparation.
Prokhorov, A. M.; Kozhevnikov, V.N.; Kopchuk, D.S.; Bernard, H.; Le Bris, N.; Tripier, R.; Handel, H.; Kozhevnikov, D. N.
Tetrahedron, 2011, 67, (3), 597-607, DOI:10.1016/j.tet.2010.11.058
21 January 2011

 Cationic Lipothiophosphoramidates for in vitro gene delivery: synthesis, physico-chemical characterizations and transfection assays- comparison with lipophosphoramidates.
Fraix, A. ; Montier, T. ; Carmoy, N. ; Loizeau, D. ; Burel-Deschamps, L. ; Le Gall, T. ; Giamarchi, P. ; Couthon-Gourvès, H. ; Haelters, J.P. ; Lehn, P. ; Jaffrès, P.A.
Org. Biomol. Chem., 2011, 9, 2422-2432, DOI: 10.1039/C0OB00981D.
First published online 17 Dec 2010


 Selective gene delivery in dendritic cells with Mannosylated and Histidylated Lipopolyplexes.
Perche, F. ; Gosset, D. ; Mével, M. ; Miramon, M.L. ; Yaouanc, J.J. ; Pichon, C. ; Benvegnu, T. ; Jaffrès, P.A. ; Midoux P.
J. Drug Targeting, 2011, 19, 315-325, DOI: 10.3109/1061186X.2010.504262.
Published online: 23 Jul 2010



Polyamines pour la détection et la reconnaissance d’anions biologiquement actifs, Jacky Pouessel



 Isomerism as a remarkable tool for the design of new potentially bridging macrocycle ligands: synthesis and characterization of the [Cu(4-L1)](NO3)2.2H2O polymeric chain (4-L1 = Mono-N (4-picolyl)cyclen). El Hajj, F.; Patinec, V.; Triki, S.; Handel, H.; Marchivie, M.
Inorg. Chem. Commun., 2010, 13 (11), 1314-1316, DOI:10.1016/j.inoche.2010.07.024
November 2010

 Unexpected [1,4]-base induced phospho-Fries rearrangement.
Berchel, M. ; Salaün, J.Y. ; Couthon-Gourvès, H. ; Haelters, J.P. ; Jaffrès, P.A.
Dalton Trans., 2010, 39, 11314-11316, DOI: 10.1039/C0DT00880J.
First published online 19 Oct 2010


From flexible to constrained tris-tetraamine ligands. Synthesis, acid-base properties and structural effect on the coordination process with nucleotides.
Delépine, A. S.; Tripier, R.; Le Baccon, M.; Handel, H.
Eur. J. Org. Chem., 2010, 5380-5390, DOI: 10.1002/ejoc.201000495
Article first published online: 17 AUG 2010


Guidelines to design new spin crossover materials.
Atmani, C.; El Hajj, F.; Benmansour, S.; Marchivie, M.; Triki, S.; Conan, F.; Patinec, V.; Handel, H.; Dupouy, G.; Gómez-García, C. J.
Coord. Chem. Rev., 2010, 254 (13-14), 1559–1569, DOI:10.1016/j.ccr.2009.11.004
Published July 2010

 DODAG; A Versatile New Cationic Lipid that Mediates Efficient Delivery of pDNA and siRNA.
Mevel, M.; Kamaly, N.; Carmona, S.; Oliver, M.H.; Jorgensen, M.R.; Crowther, C.; Salazar, F.H.; Marion, P.L.; Fujino, M.; Natori, Y.; Arbuthnot, P.; Yaouanc, J.J.; Jaffrès, P.A. ;.Miller, A. D.
J. Control Release, 2010, 143, 222-232, DOI: 10.1016/j.jconrel.2009.12.001.
Published 19 April 2010

 Highly efficient gene transfer into hepatocyte-like HepaRG cells: new means for drug metabolism and toxicity studies.
Laurent, V. ; Fraix, A. ; Montier, T. ; Cammas-Marion, S. ; Ribault, C. ; Benvegnu, T. ; Jaffrès, P.A. ; Loyer, P.
Biotechnology J., 2010, 5, 314-320, DOI: 10.1002/biot.200900255.
Article first published online: 8 MAR 2010

 Construction of S,N,S monoanionic Pincer ligand with a pyrrole core by sequential [1,2] phospho-fries rearrangement. Characterization of palladium and silver coordination complexes.
Fraix, A. ; Lutz, M. ; Spek, A.L. ; Klein Gebbink, R.J.M. ; van Koten, G. ; Salaün, J.Y. ; Jaffrès, P.A.
Dalton Trans., 2010, 39, 2942-2946, DOI: 10.1039/b923351b.
First published online 05 Feb 2010

 A novel cationic lipophosphoramidate with di-unsaturated lipid chains : synthesis, physico-chemical and transfection activities.
Le Gall, T. ; Loizeau, D. ; Picquet, E. ; Carmoy, N. ; Yaouanc, J.J. ; Deschamps, L. ; Delépine, P. ; Giamarchi, P. ; Jaffrès, P.A. ; Lehn, P. ; Montier T.
J. Med. Chem. 2010, 53, 1496-1508, DOI: 10.1021/jm900897a.
Publication Date (Web): January 29, 2010


Towards Fluoride sensing with Positively Charged Lanthanide Complexes.
Tripier, R.; Platas-Iglesias, C.; Boos, A.; Morfin, J.F.; Charbonnière, L.
Eur. J. I. Chem., 2010, 2735–2745, DOI: 10.1002/ejic.200901045
Article first published online: 21 JAN 2010



 Synthèse, caractérisation et formulation de nouveaux vecteurs phospholipidiques soufrés pour une application en transfert de gènes. Fraix Aurore


 Polyazamacrocycles fonctionnalisés pour la conception de nouvelles architectures moléculaires : extension aux complexes à transition de spin, El Hajj Fatima



 Thiophosphoramidates : une nouvelle famille de lipides pour la vectorisation d’acides nucléiques
A. Fraix, T. Montier, P. Lehn, P.A. Jaffrès
Brevet U.S., 2010, N° 61/389,959 ; Patent PCT/EP2011/067423

 Construction modulaire de lipides fluorescents et de lipides fluorescents ciblants
M. Berchel, J.P. Haelters, H. Couthon-Gourvès, P.A. Jaffrès
Brevet U.S., 2010, 15-07-2010, US 61/363,032 ; PCT/EP2011/061788

 Composés modulateur de l’activité du canal SK3 – action antimétastatique
J.P. Haelters, B. Corbel, G. Simon, C. Vandier, M. Potier, V. Joulin, P. Bougnoux. EP10305169.4



 Application of a base-induced [1,2]-rearrangement to synthesize bidentate S(sp2)-N monoanionic ligands : Characterization of Silver and Palladium complexes.
Marie, S. ; Lutz, M. ; Spek, A.L. ; Klein Gebbink, R.J.M. ; van Koten, G. ; Kervarec, N. ; Michaud, F. ; Salaün, J.Y. ; Jaffrès, P.A.
J. Organomet. Chem. 2009, 694, 4001-4007, DOI: 10.1016/j.jorganchem.2009.08.035.
Published 1 December 2009


Bismuth (III) coordination to cyclen and cyclam bearing four appended groups.
Morfin, J. F.; Lebaccon, M.; Tripier, R.; Handel, H.
Polyhedron, 2009, 28 (11), 3691-3698, DOI:10.1016/j.poly.2009.08.003
16 November 2009

 Remarkable thermal stability of Eu(4-phosphonobenzoate): Structure investigations and luminescence properties.
Rueff, J.M. ;. Barrier, N. ; Boudin, S. ; Dorcet, V. ; Caignaert, V ; Boullay, P. ; Hix, G.B. ; Jaffrès P.A.
Dalton Trans., 2009, 10614-10620, DOI: 10.1039/b913590c.
First published online 02 Nov 2009

 Lead (II) hybrid materials from 3- or 4- phosphonobenzoic acid.
Rueff, J.M.; Perez, O. ; LeClaire, A., Couthon-Gourvès, H.; Jaffrès, P.A.
Eur. J. Inorg. Chem. 2009, 4870-4876, DOI: 10.1002/ejic.200900430.
Article first published online: 1 OCT 2009


 A Tris-Macrocycle with Proton Sponge Characteristics as Efficient Receptor for Inorganic Phosphate and Nucleotide Anions.
Bencini, A.; Biagini, S.; Giorgi, C.; Handel, H.; Le Baccon, M.; Mariani, P.; Paoletti, P.; Rossi, P.; Tripier, R.
Eur. J. Org. Chem., 2009, 5610-5621, DOI: 10.1002/ejoc.200900770
Article first published online: 28 SEP 2009


 Macrocycle-Based Spin Crossover Materials.
El Hajj, F.; Sebki, G.; Patinec, V.; Marchivie, M.; Triki, S.; Handel, H.; Tripier, R.; Gómez-García, C. J., Coronado, E.
Inorg. Chem., 2009, 48 (21), 10416-10423, DOI: 10.1021/ic9012476
Publication Date (Web): September 25, 2009

 3,5-diphosphonobenzoic acid : a new rigid hetero-trifunctional building bloc to design Metal Organic Framework. Illustration with the chararacterization of Cu5[(O3P)2-C6H3-CO2]2(H2O)6.
Rueff, J.M. ; Perez, O. ; Simon, C ; Couthon-Gourvès, H. ; Lorilleux, C. Jaffrès, P.A.
Cryst. Growth Des. 2009, 9, 4262-4268, DOI: 10.1021/cg900811k.
Publication Date (Web): September 22, 2009


ATP and triphosphate anions complexation by bis-linear tetraamines: strong interactions at neutral pH.
Delépine, A.-S.; Tripier, R.; Le Bris, N.; Bernard, H.; Honraedt, A.; Handel, H.
Inorg. Chim. Acta, 2009, 302, 3829-3834, DOI:10.1016/j.ica.2009.05.003
1 August 2009

 Modeling [FeFe] hydrogenase: Synthesis and protonation of a diiron dithiolate complex containing a phosphine-N-heterocyclic-carbene ligand.
Morvan, D. ; Capon, J.F. ; Gloaguen, F. ; Pétillon, F.Y. ; Schollhammer, P. ; Talarmin, J. ; Yaouanc, J.J. ; Michaud, F. ; Kervarec, N.
J. Organomet. Chem., 2009, 694, 2801-2807, DOI: 10.1016/j.jorganchem.2009.01.018
Published 1 August 2009


 Selective mono-N-alkylation of triethylenetetraamine. A new versatile route to polylinear aza-ligands.
Delépine, A.-S.; Tripier, R.; Bernard, H.; Le Bris, N.; Handel, H.
Tetrahedron Letters, 2009, 2521-2524, DOI:10.1016/j.tetlet.2009.03.088
27 May 2009

 Chemical vectors for gene delivery: A Current Review on polymers, peptides and lipids containing histidine or imidazole as nucleic acids carriers.
Midoux, P.; Pichon, C. ; Yaouanc, J.J ; Jaffrès, P.A.
Br. J. Pharmacol. 2009, 157, 166-178. (review), DOI: 10.1111/j.1476-5381.2009.00288.x.
Article first published online: 28 APR 2009


 Synthesis of a new linear-cyclic ditopic polyaza-ligand with a xylenyl linker.
Le Bris, N.; Bernard, H.; Chamas, Z.; Handel, H.
Synth. Commun., 2009, 39 (11), 1992-2000, DOI: 10.1080/00397910802630203
Published online: 27 Apr 2009

 The dimeric unit [La(H2O)4(m-PO3C6H4COOH)(m-PO2(OH)C6H4COOH)(m-PO(OH)2C6H4COOH)]2 as building block of layered hybrid material.
Rueff, J.M. ; Leclaire, A. ; Jaffrès, P.A.
Solid State Sciences, 2009, 11, 812-817, DOI:10.1016/j.solidstatesciences.2008.12.008.
Published April 2009


Bismuth (III) Complexes with Tetra-Pyridylmethyl-Cyclen.
Morfin, J. F.; Lebaccon, M.; Tripier, R.; Handel, H.
Inor. Chim. Acta, 2009,362, 1781-1786, DOI:10.1016/j.ica.2008.08.013
20 April 2009

 Elaboration and characterization of novel PA12/layered titanoniobates nanocomposites.
Chausson, S.; Retoux, R.; Rueff, J.M.; Le Pluart, L.; Madec, P.J.; Jaffrès, P.A.
J. Mater. Res., 2009, 24, 3358-3371, DOI: 10.1557/jmr.2009.0410.

 Synthesis of phosphorus-containing chitosan derivatives.
Lebouc, F. ; Dez, I. ; Gulea, M. ; Madec, P.J. ; Jaffrès, P.A.
Phosphorus, Sulfur Silicon Relat. Elem., 2009, 184, 872-889 (Publication on invitation), DOI: 10.1080/10426500802715585
Published online: 26 Mar 2009

 Synthesis of methylene diphosphonates from carbon disulfide and phosphites via desulfurization: a mechanistic study.
Heuzé, B. ; Lemarié, M. ; Vazeux, M. ; Gulea, M. ; Masson, S. ; Sene, A. ; Jaffrès, P.A., Alberti A., Macciantelli D.
Phosphorus, Sulfur Silicon Relat. Elem., 2009, 184, 820-829. (Publication on invitation), DOI:10.1080/10426500802715528.
Published online: 26 Mar 2009

 Magnetic Bistability and Thermochromism in a Molecular CuII Chain.
Setifi,, F.; Benmansour, S.; Marchivie, M.; Dupouy, G.; Triki, S. ; Sala-Pala, J. ; Salaun, J.Y.; Gomez-Garcia C.J. Pillet, S.; Lecomte, C.; Ruiz E.
Inorg. Chem. 2009, 48, 1269-1271, DOI: 10.1021/ic802292s.
Publication Date (Web): January 23, 2009

 Meta-phosphonobenzoic acid and copper(II) as precursors of helical chain and lamellar hybrid materials.
Rueff, J.M. ; Caignaert, V. ; Leclaire, A. ; Simon, C. ; Haelters, J.P. ;. Jaffrès, P.A.
CrystEngComm, 2009, 11, 556-559, DOI: 10.1039/B816132C.
First published online 07 Jan 2009

 Phosphine Addition to Pyruvoyl Ligands of Iron Complexes; Formation of Zwitterionic Metallalactones.
Salaün, J.Y. ; Rumin, R. ; Setifi, F. ; Triki, S. ; Jaffrès, P.A.
Organometallics, 2009, 28, 216-224, DOI: 10.1021/om800804b.
Publication Date (Web): December 12, 2008



 Polyamines pour la reconnaissance d'anions d'intérêt biologique, Delépine Anne-Sophie



 Synthesis of O,O-Diethyl arylthiophosphonate from O-Aryl-O,O-diethylthiophosphate”
Dieng, T. ; Fraix, A. ; Salaün, J.Y. ; Dez, I. ; Klein Gebbink, R.J.M. ; van Koten, G. ; Jaffrès, P.A.
Synlett, 2008, 3121-3124.

 “A novel polynitrile ligand with different coordination modes: Synthesis, structure and magneticproperties of the series [M(tcnoprOH)2(H2O2)2] (M= Mn, Co and Cu) (tcnoprOH- = [(NC)2CC(OCH2CH2CH2OH)C(CN)2]-)"
Benmansour, S. ; Setifi, F. ; Gomez Garcia, C.J.; Triki, S. ; Coronado, E. ; Salaün, J.Y.
J Mol. Struct. 2008 (N° special dédié à Cotton), 890, 255-262, DOI:10.1016/j.molstruc.2008.04.044.
Published 12 November 2008

 Fluorescence study of lipid-based DNA carriers properties : influence of cationic lipid chemical structure
Burel-Deschamps, L. ; Ayadi, F. ; Lounissi, S. ; Mével, M. ; Clément, J.C. ; Yaouanc, J.J. ; Jaffrès, P.A. ; Giamarchi, P.
J. Fluoresc., 2008, 18, 835-841, DOI: 10.1007/s10895-008-0312-7.
Published September 2008

 Influence of a pyrazyl linker on the physicochemical properties of homodinuclear bis(cyclen) and bis(cyclam) complexes.
El Ghachtouli, S.; Cadiou, C.; Déchamps-Olivier, I.; Chuburu, F.; Aplincourt, M.; Roisnel, T.; Turcry, V.; Patinec, V.; Le Baccon, M.; Handel. H.
Eur. J. Inorg. Chem., 2008, 4735-4744, DOI: 10.1002/ejic.200800149
Article first published online: 12 SEP 2008

 TEM/SEM Characterisation of hybrid titanoniobiates used as fillers for thermoplastic nanocomposites
Retoux, R. ; Chausson, S., Le Pluart, L. ; Rueff, J.M., Jaffrès, P.A.
EMC2008 Vol. 2, S. Richter & A. Schwedt Editors, Springers, 2008, 785-786, DOI: 10.1007/978-3-540-85226-1_393. 
Published September 2008

 The Key Role of the Intermolecular π−π Interactions in the Presence of Spin Crossover in Neutral [Fe(abpt)2A2] Complexes (A = Terminal Monoanion N Ligand)
Dupouy, G. ; Marchivie, M. ; Triki, S. ; Sala-Pala, J. ; Salaün, J.Y. ; Gómez-García,C.J. ; Guionneau, P.
Inorg Chem. 2008, 47, 8921–8931, DOI: 10.1021/ic800955r.
Publication Date (Web): August 8, 2008

 New planar polynitrile dianion and its first coordination polymer with unexpected Short M…M contacts (tcno2-= [(NC)2CC(O)C(CN)2]2-).
Atmani, C. ; Setifi, F. ; Benmansour, S. ; Triki, S. ; Marchivie, M. ; Salaün, J.Y. ; Gómez-García, C.J.
Inorg Chem.Commun. 2008, 11, 921-924, DOI:10.1016/j.inoche.2008.04.038.
Published August 2008

 "Progress in cationic lipid-mediated gene transfection: a series of bio-inspired lipids as an example"
Montier, T. ; Benvegnu, T. ; Jaffrès, P.A.; Yaouanc, J.J.; Lehn, P.
Curr. Gene Ther., 2008, 8, 296-312. (Review), DOI: 10.2174/156652308786070989.

 Meta-phosphonobenzoic acid: a rigid bifunctional precursor for the design of hybrid materials
Rueff, J.M.; Caignaert, V.; Chausson, S.; Leclaire, A.; Simon, C.; Perez, O.; le Pluart, L.; Jaffrès, P.A.
Eur. J. Inorg. Chem., 2008, 4117-4125, DOI: 10.1002/ejic.200800483.
Article first published online: 5 AUG 2008

 "(N,N) versus (N,S) chelation of palladium in asymmetric allylic substitution using bis(thiazolines) ligands; a theoretical and experimental study “
Betz, A. ; Yu, Y. ; Reiher, M. ; Gaumont, A.C. ; Jaffrès, P.A. ; Gulea, M.
J. Organomet. Chem., 2008, 693, 2499-2508, DOI:10.1016/j.jorganchem.2008.04.044.
Published 15 July 2008

 Synthesis of functionalised alkoxyalkylidene gem-bisphosphonates
Haelters, J.P. ; Couthon-Gourvès, H. ; Le Goff, A. ; Simon, G. ; Corbel, B. ; Jaffrès, P.A.
Tetrahedron, 2008, 64, 6537-6543, DOI: 10.1016/j.tet.2008.04.052.
Published 30 June 2008

 Cationic lipids based on phosphonate and phosphoramidate chemistry : synthesis and application to gene therapy.
Mével M., Yaouanc J. J., LaurentP., Clément J. C., CartierD., Jaffrès P. A., Montier T., Delépine P., Le Gall T., LehnP.,Pichon C., Midoux P, C. FérecC.
Phosphorus, Sulfur Silicon Relat. Elem., 2008, 183, 460-468, DOI:10.1080/10426500701761300.
Published online: 20 Jun 2008


 Novel neutral imidazole-lipophosphoramides for transfection assays.
Mével, M. ; Neveu, C. ; Gonçalves, C. ; Yaouanc, J. J. ; Pichon C., Jaffrès, P. A. Midoux P,
ChemCommun, 2008, 3124-3126, DOI: 10.1039/B805226C.
First published online 16 Jun 2008


 «Synthesis and Transfection Activity of New Cationic Phosphoramidate Lipids: High efficiency of an Imidazolium derivative»
Mével, M. ; Breuzard, G. ; Yaouanc, J. J. ; Clément, J. C. ; Lehn, P. ; Pichon, C. ; Jaffrès, P.A. ; Midoux, P.
ChemBioChem , 2008, 9, 1462-1471, DOI: 10.1002/cbic.200700727.
Article first published online: 2 MAY 2008


 Electrochemically-driven conformational shift in mono- and di-copper constrained macrotricyclic cyclen receptors.
Doménech, A.; García-España, E.; Bernier, N.; Tripier, R.; Handel, H.
Dalton Transactions, 2008, 3169-3177, DOI: 10.1039/B718163A
First published online 30 Apr 2008


 Synthesis of a new ditopic ligand possessing linear and cyclic tetraaza-subunits.
Prokhorov, A.; Bernard, H.; Le Bris, N.; Marquet, N.; Handel, H.
Synth. Commun., 2008, 38, 1589-1600, DOI: 10.1080/00397910801929481
Published online: 24 Apr 2008


 Cyclen based bismacrocycles for biological anions recognition. A potentiometric and NMR study of AMP, ADP and ATP nucleotides complexation.
Delépine, A. S.; Tripier, R.; Handel, H.
Org. Biomol. Chem. 2008, 1743-1750, DOI: 10.1039/B719514A
First published online 26 Mar 2008.

 Ethane-1,1,2-trisphosphonic acid hemihydrate
Delain-Bioton, L. ; Lohier, J.F. ; Villemin, D. ; Sopkova, J. ; Hix, G.B. Jaffrès, P.A.
Acta cryst, 2008, C64, o47-o49, DOI:10.1107/S0108270107064098.
Published February 2008


 Polyamines and applications. A look at the first workshop in linear and cyclic polyamines chemistry.
Denat, F.; Deniaud, D.; Tripier, R.
L’Actualité Chimique, 2008, 316, 10-21. lien
Published : February 2008

 An efficient and straightforward access to sulfur substituted [2.2]paracyclophanes: application to stereoselective Sulfenate Salt Alkylation.
Lohier, J.F. ; Foucoin, F. ; Jaffrès, P.A. ; Garcia, J.I. ; Sopková-de Oliveira Santos, J. ; Perrio, S. ; Metzner, P.
Org. Lett. 2008, 10, 1271-1274, DOI: 10.1021/ol800161m.
Publication Date (Web): February 15, 2008


 Polyethylene Nanocomposites based on intercalation of N-alkyl amines within KTiNbO5 Structure Polymer
Chausson, S.; Caignaert, V. ; Retoux, R. ; Rueff, J.-M. ; Le Pluart, L. ; Madec, P.J. ; Jaffrès, P.A.
Polymer, 2008, 49, 488-496, DOI: 10.1016/j.polymer.2007.11.050.
Published 21 January 2008


 Synthesis, crystal structure and thermal properties of phosphorylated cyclotriphosphazenes
Lejeune, N. ; Dez, I. ; Jaffrès, P.A. ; Lohier, J.F. ; Madec, P.J. ; Sopkova-de Oliveira, J.
Eur. J. Inorg. Chem. 2008, 138-143, DOI: 10.1002/ejic.200700785. 
Article first published online: 8 NOV 2007



Complexation du bismuth III par les macrocycles polyazotés en vue d'une application en alpha-radio-immunothérapie, Morfin Jean-François



Towards the synthesis of NH- and N-alkylated derivatives of meridianines.
Simon, G.; Couthon-Gourves, H.; Haelters, J-P. ; Corbel, B. ; Kervarec, N. ; Michaud, F. ; Meijer, L.
Heterocycl. Chem. 2007, 44, 1-9, DOI: 10.1002/jhet.5570440407.

 Cholesteryl or lipophosphoramidate as lipidic part of lipospermines for gene delivery: a comparative study. Lamarche, F.; Mével, M.; Montier, T.; Burel-Deschamps, L.; Giamarchi, P.; Tripier, R.; Cartier, D. ; Lehn, P. ; Clément, J.-C.
Bioconjugate Chem., 2007, 18(5), 1575-1582,

 A new biomimetic-like aromatization of the cyclic end groups of terpenoids with stereospecific migration of one of the methyl groups : a convenient route to isorenieratene (f,f-carotene).
A. Valla, Z. Andriamialisoa, B. Valla, R. Labia, R. Le Guillou, L. Dufossé, D. Cartier.
Eur. J. Org. Chem., 2007, 711-715, DOI: 10.1002/ejoc.200600794.
Article first published online: 27 NOV 2006


 New Multidimensional Coordination Polymers with Mu2 and n2 dcno Cyano−carbanions ligands {dcno− = [(NC)2CC(O)O(CH2)2OH]−}
Benmansour, S. ; Setifi, F. ; Triki, S. ; Salaün, J.Y. ; Vandevelde, F. ; Sala−Pala, J. ; Gomez−Garcia, C.J. ; Roisnel, T.
Eur. J. Inorg. Chem. 2007, 186−194, DOI: 10.1002/ejic.200600449.
Article first published online: 21 NOV 2006


 New Coordination polymers based on a triply bridged dicarboxylate ligand: Synthesis, Structure and Magnetic Properties of the Adipo Complex [Cu4(bipy)4(adip)3](tcnoet)2.2H2O; {bipy = C10H8N2; adip2− = [O2C(CH2)4CO2]2−; tcnoet− = [(CN)2CC(OEt)C(CN)2]− ».
Setifi, F. ; Gomez−Garcia, C.J. ; Marchivie, M. ; Salaün, J.Y. ; Mustapha, M.
Inorg. Chim. Acta, 2007, 360, 3879−86, DOI:10.1016/j.ica.2007.03.005.
Published 1 October 2007


 Status Report on Organo-metallic Beams at GANIL
Lehérissier, P. ; Barué, C. ; Canet, C. ; Dubois, M. ; Dupuis, M. ; Flambard, J.L. ; Jaffrès, P.A. ; .Jardin, P. ; Gaubert, G. ; Lecesne, N. ; Lemagnen, F. ; Leroy, R. ; Pacquet, J.Y.
High Energy Physics And Nuclear Physics, 2007, 31(S1), 85-89.


 Synthesis of Triazole-alkyl-phosphonate from ω-Azidoalkylphosphonates and ω-Alkynylphosphonates
Delain-Bioton, L. ; Villemin, D. ; Lohier, J.F. ; Sopkova, J. ;Jaffrès, P.A.
Tetrahedron, 2007, 63, 9677-84, DOI:10.1016/j.tet.2007.07.024.
Published 24 September 2007


 Proton-sponge behaviour of new pendant armed cross-bridged bis-cyclens. Synthesis, NMR, X-ray and potentiometric investigations.
Bernier, N.; Tripier, R.; Patinec, V. ; Le Baccon, M.; Handel, H.
Comptes Rendus de Chimie, 2007, 10 (9), 832-838, DOI:10.1016/j.crci.2007.03.016
Published September 2007

 Dicationic Lipophosphoramidates as DNA carriers
Mével, M. ; Montier, T.; Lamarche, F. ; Delépine, P.; Le Gall, T. ; Yaouanc, J. J.; Jaffrès, P. A. ; Cartier, D.; Lehn, P. ; Clément, J. C.
Bioconjugate Chem., 2007, 18, 1604-1611, DOI: 10.1021/bc070089z.
Publication Date (Web): August 3, 2007


 Lipophosphoramidates as Lipidic Part of Lipospermines for Gene Delivery.
Lamarche F., Mével M., Montier T., Burel-Deschamps L., Giamarchi P., TripierR., Le Gall T., Cartier D., Lehn P., Clément J. C., Jaffrès, P.A.
Bioconjugate Chem. , 2007, 18, 1575-1582, DOI: 10.1021/bc070070w.
Publication Date (Web): August 3, 2007


Monopropionate derivatives of DOTA4 and DTPA5- : kinetics of formation and dissociation of their lanthanide(III) complexes.
Balogh, E.; Tripier, R.; Fouskova, P.; Reviriego, F.; Handel, H.; E. Tóth,
Dalton Trans. 2007, 3572-3581, DOI: 10.1039/B706353A
First published online 26 Jun 2007


A potentiometric and NMR investigation of triphosphate recognition by linear and bis-macrocyclic octaamines possessing a 1,4-xylylenyl linker.
Le Bris, N.; Bernard, H.; Tripier, R.; Handel, H.
Inorg. Chim. Acta, 2007, 360, 3026-3032, DOI:10.1016/j.ica.2007.02.041
10 June 2007

 New syntheses of retinal and its acyclic analogy g-retinal by an extended aldol reaction with a C6 building block that incorporates a C5 unit after decarboxylation. A Formal route to lycopene and b-carotene.
A. Valla, B. Valla, R. Le Guillou, D. Cartier, L. Dufossé, R. Labia.
Helvetica Chim. Acta, 2007, 90, 512-520, DOI: 10.1002/hlca.200790053.
Article first published online: 19 MAR 2007


 N-Heterocyclic Carbene Ligands in Nonsymmetric Diiron Models of Hydrogenase Active Sites.
Morvan, D.; Capon, J.-F.; Gloaguen, F.; Le Goff, A.; Marchivie, M.; Michaud, F.; Schollhammer, P.; Talarmin, J.; Yaouanc, J.-J.; Pichon, R.; Kervarec, N.
Organometallics; 2007; 26, 2042-2052, DOI: 10.1021/om061173l.
Publication Date (Web): March 16, 2007


 A supramolecular ladderlike structure formed by the auto assembly of benzene-1,3,5-triphosphonic acid.
Hix, G.B. ; Caignaert, V. ; Rueff, J.M. ; Le Pluart, L. ; Warren, J.E. ; Jaffrès, P.A.
Crystal Growth & Des., 2007, 7, 208-211, DOI: 10.1021/cg060813k.
Publication Date (Web): February 7, 2007


 w-Alkynes-Mono and Di-phosphonates: Synthesis and Sonogashira Cross Coupling Reaction with Aryl halides.
Delain-Bioton, L. ; Villemin, D. ; Jaffrès, P.A.
Eur. J. Org. Chem., 2007, 1274-1286, DOI: 10.1002/ejoc.200600556.
Article first published online: 19 JAN 2007


 Diastereoselective Michael additions to α,β–unsaturated α-sulfinyl phosphonates in the thiolane series
Łyżwa, P. ; Jankowiak, A. ; Kwiatkowska, M. ; Mikołajczyk, M. ; Kiełbasiński, P. ; Betz, A. ; Jaffrès, P.A. ; Gaumont, A.C. ; Gulea, M.
Tetrahedron Lett., 2007, 48, 351-355, DOI:10.1016/j.tetlet.2006.11.098.
Published 15 January 2007


 Complexation of the triphosphate anion: tuning the structure of cyclen based macrotricycles with 1,2-dimethylbenzene and 2,6-dimethylpyridine linkers. A potentiometric and NMR study.
Develay, S.; Tripier, R.; Bernier, N.; Le Baccon, M.; Patinec, V.; Serratrice, G.; Handel, H.
Dalton Trans. 2007, 1038-1046, DOI: 10.1039/B616862K
First published online 12 Jan 2007



 Synthèses de sels d’imidazolium fonctionnalisés précurseurs de carbènes N-hétérocycliques et applications en chimie organométallique. Morvan Didier


 Synthèses et études de lipophosphoramidates neutres et cationiques pour la vectorisation de l’ADN. Mével Mathieu


 Macrocycles en série tétraazacycloalacnes : synthèse et étude de complexation de dérivés du cyclen, Bernier Nicolas



 Nouvelles compositions lipophiles et leurs utilisations
Mével, M. ; Clément, J.C. ; Yaouanc, J.J. ; Pichon, C. ; Midoux, P.
Brevet Français, Fr 07 57955. (28 septembre 2007)



Antioxidation activity of several diphosphonates in thermoxidative stability of LDPE
Jipa, S.; Gorghiu, L.M.; Dumitrescu, C.; Bumbarn R.L.; Olteanu, R.L.; Couthon-Gourves, H.
Journal of Optoelectronics and Advanced Materials, 2006, 8 (2), 654-658, lien


Synthesis of novel diethyl indolylphosphonates and tetraethyl indolyl-1,1-bisphosphonates by Michael additions.
Couthon-Gourves, H.; Simon, G.; Haelters, J-P. ; Corbel, B.
Synthesis, 2006 1, 81-88, DOI: 10.1055/s-2005-921757

Synthesis of three dissymmetrical pentaamines via bisaminals of linear tetraamines.
Claudon, G.; Bernard, H.; Le Bris, N.; Handel, H.
J. Chem. Res., 2006, 356-358, lien

 Cyclohexanedione bisaminals as intermediates for cyclen, homocyclen, and cyclam synthesis.
Prokhorov, A.; Le Bris, N.; Bernard, H.; Claudon, G.; Handel, H.
Synth. Commun., 2006, 36, 3271-3282, DOI: 10.1080/00397910600910633
Published online: 24 Nov 2006

Copper sorption onto a lignocellulosic substrate from wheat bran impregnated with a lipophilic tetraazamacrocycle.
Sayen, S.; Chuburu, F.; Guillon, E.; Aplincourt, M.; Handel, H.; Le Baccon, M.; Patinec, V.
Colloids and Surfaces A: Physicochem. Eng. Aspects, 2006, 289 (1-3), 126-132, DOI:10.1016/j.colsurfa.2006.04.020
15 October 2006

Unexpected aggregation in aqueous solution of neutral xylene-cored dinuclear GdIII chelates.
Costa, J.; Balogh, E.; Turcry, V.; Tripier, R.; Le Baccon, M.; Chuburu, F.; Handel, H.; Helm, L.; Tóth, E.; Merbach, A. E.
Chem. Eur. J., 2006, 12, 6841-6851, DOI: 10.1002/chem.200501335
First published: 13 June 2006

Reaction of polyamines with diethyloxalate: a convenient route for the synthesis of tetraazacycloalkanes.
Denat, F.; Tripier, R.; Boschetti, F.; Espinosa, E.; Guilard, R.
Arkivoc, 2006, 4, 212-233, DOI:
Published on 2006-05-08

Host-guest interaction between cyclen based macrotricyclic ligands and phosphate anions. A potentiometric investigation.
Develay, S.; Tripier, R.; Le Baccon, M.; Patinec, V.; Serratrice, G.; Handel, H.
Dalton Trans. 2006, 3418-3426, DOI: 10.1039/B517695F
First published online 06 Apr 2006

New side-bridged bismacrocycles and cross-bridged macrotricycles. Syntheses and Cu(II) complexation study.
Bernier, N.; Allali, M.; Tripier, R.; Conan, F.; Patinec, V.; Develay, S.; Le Baccon, M.; Handel, H.
New. J. Chem., 2006, 1, 435-441, DOI: 10.1039/B515150C
First published online 30 Jan 2006

Nickel(II) complexes of cyclen- and cyclam- pyridine : topological reorganisations induced by electron transfer.
El Ghachtouli, S.; Cadiou, C.; Déchamps-Olivier, I.; Chuburu, F.; Aplincourt, M.; Patinec, V.; Le Baccon, M.; Handel, H.; Roisnel, T.
New J. Chem., 2006, 30, 392-398, DOI: 10.1039/B515107D
First published online 20 Jan 2006